导师姓名： 黄翼然 专业代码： 100210
性别： 男 专业名称： 外科学
培养单位： 附属仁济医院 三级学科/
专业领域： 泌尿外
导师类型： 博士生导师 专业学位导师： 兼
联系方式： E-Mail:huangyiran@renji.com
邮编： 200127 邮箱地址： hyrrenji2@yahoo.com.cn

研究方向 (点击浏览详细信息)
泌尿系肿瘤的代谢特征和分子调控机制

社会任职
国家自然科学基金评审专家
《中国男科学杂志》常务副主编
中华医学会男科学会副主任委员
上海市医学会男科学会主任委员
中华医学会泌尿外科分会常委
中华医师学会泌尿外科分会委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 蛋白质精氨酸甲基转移酶1在肾透明细胞癌发生发展中的作用及干预研究 国家自然基金-面上 2015-01~2018-12 72万元 课题负责人
** SCD1在肾透明细胞癌缺氧脂质代谢中的调节作用和分子机制研究 国家自然基金-面上 2013-01~2016-12 70万元 课题负责人
2012CB932604 前列腺癌纳米检测技术的临床应用评价 国家级973－国家重大研究计划 2012-05~2014-06 40万元 课题参与人
** 炎症微环境与EMT在前列腺癌浸润转移和耐药中的作用 国家自然基金重大研究计划培育项目 2012-01~2014-12 60万元 主要责任人
** VHL-HIF-缺氧反应基因轴相关MicroRNA在肾癌中表达及其意义 国家自然基金面上项目 2011-01~2013-12 32万元 主要责任人
10JC** 肾癌的代谢特征和调控机制研究 市科委基础重点 2010-10~2013-09 30万元 主要责任人
SHDC** 早期肾癌保留肾单位的微创治疗 申康中心新兴前沿技术联合公关项目 2010-04~2013-03 200万元 主要责任人
Th17细胞亚群和白细胞介素17在Ⅲ型慢性前列腺炎发病机制中的作用 上海市科委生物医药重点项目 2009-07~2012-06 20万元 主要责任人
** 类泛素蛋白酶1在肾癌缺氧糖酵解中的调节作用研究 国家自然基金委,面上项目 2009-01~2011-12 31万元 课题负责人
男性生殖的基础与应用研究 上海市科委，国际合作项目 2008-09~2010-09 30万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Huang J, Zhang J, Wang Y, Kong W, Xue W, Liu D, Chen Y, Huang Y. （通讯作者） Comparing Zero Ischemia Laparoscopic Radio Frequency Ablation Assisted Tumor Enucleation and Laparoscopic Partial Nephrectomy for Clinical T1a Renal Tumor: A Randomized Clinical Trial. J Urol. 2016 195(6):1677-83.
Xu Y, Dong B, Huang J, Kong W, Xue W, Zhu Y, Zhang J, Huang Y. （通讯作者） Sphingosine kinase 1 is overexpressed and promotes adrenocortical carcinoma progression. Oncotarget. 2016 19;7(3):3233-44.
Wu XR, Chen YH, Chen W, Kong W, Huang JW, Zhang J, Xue W, Liu DM, Huang YR. （通讯作者） GFOD1 and peejar are promising markers for clear-cell renal cell carcinoma disease progression. Oncotarget. 2016 19;7(5):3233-44.
Huang J, Kong W, Zhang J, Chen Y, Xue W, Liu D, Huang Y. （通讯作者） c-Myc modulates glucose metabolism via regulation of miR-184/PKM2 pathway in clear-cell renal cell carcinoma. Int J Oncol. 2016 6(5):668-78.
Ding Y, Kong W, Zhang J, Dong B, Chen Y, Xue W, Liu D, Huang Y. （通讯作者） Spherical cap surface model: A novel method for predicting renal function after partial nephrectomy. Int J Urol. 2016 23(8):667-72
Yuan X, Dong B, Xu Y, Dong L, Huang J, Zhang J, Chen Y, Xue W, Huang Y. （通讯作者） TIKI2 is upregulated and plays an oncogenic role in renal cell carcinoma. Oncotarget. 2016 7(13):17212-9.
Dong L, Huang J, Huang L, Shi O, Liu Q, Chen H, Xue W, Huang Y. （通讯作者） Thyroid-Like Follicular Carcinoma of the Kidney in a Patient with Skull and Meningeal Metastasis: A Unique Case Report and Review of the Literature. Medicine (Baltimore). 2016 95(15):e3314
Liang Ying1, Jun Lin2, Feng Qiu1, Ming Cao1, Haige Chen1, Zhihong Liu3 and Yiran Huang1 Epigenetic repression of regulator of G-protein signaling 2 by ubiquitin-like with PHD and ring-?nger domain 1 promotes bladder cancer progression the FEBS Journal 2015 (2015) 174–182 a
Wang H, Zhang Y, Lu Y, Song J, Huang M, Zhang J, Huang Y. （通讯作者） The role ofstearoyl-coenzyme A desaturase 1 in clear cell renal cell carcinoma. Tumour Biol. 2015 37(1):479-89.
Chen YH, Wu XR, Hu ZL, Wang WJ, Jiang C, Kong W, Chen W, Xue W, Liu DM, Huang YR. （通讯作者） Treatment of renal cell carcinoma with a level III or level IV inferior vena cava thrombus using cardiopulmonary bypass and deep hypothermic circulatoryarrest. World J Surg Oncol. 2015 13:159.
Huang J, Feldman AS, Dong L, Cornejo K, Liu Q, Dahl DM, Wu S, Blute ML, Huang Y （通讯作者）, Wu CL. Preoperative Anemia as an Independent Prognostic Indicator of Papillary Renal Cell Carcinoma. Clin Genitourin Cancer. 2015 13(5):e353-60.
Yi Ma1,2, Hao-Zheng Yang3, Bai-Jun Dong1, Han-Bing Zou3, Yan Zhou3, Xian-Ming Kong2 and Yi-Ran Huang1 （通讯作者） Biphasic regulation of autophagy by miR-96 in prostate cancer cells under hypoxia Oncotarget 2014 Vol. 5, No. 19 9169-9182
Jiahua Pan., Wei Xue., Jianjun Sha, Hu Yang, Fan Xu, Hanqing Xuan, Dong Li, Yiran Huang* （通讯作者） Incidental Prostate Cancer at the Time of Cystectomy: The Incidence and Clinicopathological Features in Chinese Patients PLOS ONE 2014 April 2014 | Volume 9 | Issue 4 | e94490
Jiwei Huang & BaiJun Dong & Jin Zhang & Wen Kong & Yonghui Chen & Wei Xue & Dongming Liu & Yiran Huang miR-199a-3p inhibits hepatocyte growth factor/c-Met signaling in renal cancer carcinoma Tumor Biol 2014 Tumor Biol. (2014) 35:5833–5843
Ye-Hua Zhu1 Xun Wang Jin Zhang Yong-Hui Chen Wen Kong Yi-Ran Huang Low Enhancement on Multiphase Contrast-Enhanced CT Images: An Independent Predictor of the Presence of High Tumor Grade of Clear Cell Renal Cell Carcinoma Genitourinary Imaging ? Original Research 2013 AJR:203, September 2014 W295 -300
Jiwei Huang,YongHui Chen,Baijun Dong,Wen Kong,Jin Zhang,Wei Xue, DongMing Liu and Yiran Huang Effect of remote ischaemic preconditioning on renal protection in patients undergoing laparoscopic partial nephrectomy: a‘blinded’ randomised controlled trial British Journal of Urology 2013 2013 BJU International | 112,74–80
Jiwei Huang, Xiaoying Yao, Jin Zhang,Baijun Dong,Qi Chen, Wei Xue,Dongming Liu and Yiran Huang Hypoxia-induced downregulation of miR-30c promotes epithelial-mesenchymal transition in human renal cell carcinoma Cancer Science 2013 Cancer Sci | December 2013 | vol. 104 | no. 12 | 1609–1617
Kai Sun, Chen Zhao, Xiang-Feng Chen, Hye-Kyung Kim, Bo-Ram Choi, Yi-Ran Huang and Jong-Kwan Park （通讯作者） Ex vivo relaxation effect of Cuscuta chinensis extract on rabbit corpus cavernosum Asian Journal of Andrology 2012
Jianwei Lv,Yiran Huang （通讯作者）,Shiguo Zhu, Ganggang Yang, Yujian Zhang, Jing Leng, Juanjie Bo, Dongming Liu MCP-1-Induced Histamine Release from Mast Cells Is Associated with Development of Interstitial Cystitis/Bladder Pain Syndrome in Rat Models Mediators Inflamm 2012
Huang J, Zhang J, Dong B, Chen Y, Kong W, Liu Q, Xue W, Liu D, Huang YR. （通讯作者） Primitive Neuroectodermal Tumor of the Kidney: A Single-Institute Series of Six Patients from China Urol Int 2012
Hongchang Gao,Baijun Dong,Jianmin Jia,Huan Zhu,Chengfeng Diao,Zhihan Yan,Yiran Huang （通讯作者）,Xiaokun Li Application of ex vivo 1H NMR metabonomics to the characterization and possible detection of renal cell carcinoma metastases ORIGINAL PAPER 2012 (2012)138:753-761
Jianwei Lv,Yiran Huang （通讯作者）,Shiguo Zhu,Ganggang Yang,Yujian Zhang,Jing Leng,1Juanjie Bo,Dongming Liu MCP-1-Induced Histamine Release from Mast Cells IS Associated with Development of Interstitial Cystitis/Bladder Pain Syndrome in Rat Models Research Article 2012 10.1155/2012/358184
Kong W, Zhang J, Dong B, Chen Y, Xue W, Liu D, Huang YR. （通讯作者） Application of a standardized anatomical classification in a Chinese partial nephrectomy series Int J Urol 2012 19(6):551-8. doi: 10.1111/j.1442-2042
Sha J, Liang G, Pan J, Xuan H, Ping P, Li D, Bo J, Liu D, Shen W, Liu W, Huang YR. （通讯作者） Application of pyrosequencing technique for improved detection of K-Ras mutation in formalin-fixed and paraffin-embedded prostate carcinoma tissues in Chinese patients Clin Chim Acta 2012 413(19-20):1532-1535
Jin Zhang, Jia-Hua Pan, Bai-Jun Dong, Wei Xue, Dong-ming Liu, Yi-Ran Huang （通讯作者） Active surveillance of renal masses in von Hippel-Lindau disease: growth rates and clinical outcome over a median follow-up period of 56 months Familial Cancer 2012 11(2):209-214
Hailiang Zhang,Baijun Dong,Jiade Lu,Xudong Yao,Shilin Zhang,Bo Dai,Yijun Shen,Yao Zhu,Dingwei YE,Yiran Huang （通讯作者） Efficacy of sorafenib on metastatic renal cell carcinoma in Asian patients:Results from a multicenter study BMC Cancer 2009 9:249-257