导师姓名： 潘勤 专业代码： 100201
性别： 男 专业名称： 内科学
培养单位： 附属新华医院 三级学科/
专业领域： 消化系病
导师类型： 硕士生导师 专业学位导师：
联系方式： pan_qin@yeah.net
邮编： 200092 邮箱地址： pan_qin@yeah.net

研究方向 (点击浏览详细信息)
脂肪性肝病及肝纤维化

社会任职
中华肝脏病杂志特邀编委
上海市中西医结合学会器官纤维化分会委员
实用肝脏病杂志编委
World Journal of Hepatology编委
上海市消化学会生物样本库与转化医学组成员
中华肝脏病学会青年委员
中华消化学会生物样本库与转化医学组成员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** β3整合素、miR-122联合修饰肝星状细胞源性exosome以重塑"细胞间通讯网络"对肝纤维化的干预研究 国家自然基金 2015-01~2018-12 73万元 课题负责人
** 阻抑长链非编码RNA-HOTAIR以诱导肌成纤维细胞重分化对肝纤维化的防治意义 国家自然基金 2013-01~2016-12 70万元 课题负责人
** miRNA-16家族阻断肌成纤维细胞的动态更新及其对肝纤维化的干预研究 国家自然基金 2011-01~2011-12 10万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Pan Q, Fan JG Noninvasive diagnosis of nonalcoholic steatohepatitis: Emerging approaches Hepatobiliary Pancreat Dis Int 2019 18(1): 1-3
Sun F, Wang JZ, Luo JJ, Wang YQ, Pan Q （通讯作者） Exosomes in the Oncobiology, Diagnosis, and Therapy of Hepatic Carcinoma: A New Player of an Old Game Biomed Res Int 2018 2018: **
Luo JJ, Cao HX, Yang RX, Zhang RN, Pan Q （通讯作者） PNPLA3 rs139051 is associated with phospholipids metabolite profile and hepatic inflammation in nonalcoholic fatty liver disease World J Clin Cases 2018 6(10): 355-364
Zhang RN, Pan Q （通讯作者）, Zheng RD, Mi YQ, Shen F, Zhou D, Chen GY, Zhu CY, Fan JG Genome-wide analysis of DNA methylation in human peripheral leukocytes identifies potential biomarkers of nonalcoholic fatty liver disease Int J Mol Med 2018 42(1):443-452
Wu J, Zhang RN, Shen F, Yang RX, Zhou D, Cao HX, Chen GY, Pan Q （通讯作者）, Fan JG Altered DNA Methylation Sites in Peripheral Blood Leukocytes from Patients with Simple Steatosis and Nonalcoholic Steatohepatitis (NASH) Med Sci Mon 2018 24(10): 6946-6967
Xing-Ya G, Fang S, Jian-Neng C, Yu-Qin W, Qin P （通讯作者）, Jian-Gao F circRNA_** inhibits hepatocellular steatosis by normalization of PPAR signaling World J Gastroenterol 2018 24(3): 315-444
Wang JZ, Cao HX, Chen JN, Pan Q （通讯作者） PNPLA3 rs738409 underlies treatment response in nonalcoholic fatty liver disease World J Clin Cases 2018 6(8): 167-175
Sun F, Guo XY, Wang JZ, Wang YQ, Pan Q （通讯作者） Hepatic Stellate Cells Inhibit Epithelial-to-Mesenchymal Transition of Hepatoma Cells: Effect of MiR-233 Modification on Exosomes Nanosci Nanotech Let 2018 10(11):1–8
Xing-Ya G, Jian-Neng C, Fang S, Yu-Qin W, Qin P （通讯作者）, Jian-Gao F circRNA_** Prevents Hepatoxicity of Lipid Peroxidation: An Inhibitory Role against Hepatic Steatosis Oxidative Medicine and Cellular Longevity 2017 2017: **
郭行雅,章瑞南,何崇信,孙芳,范建高,潘勤 （通讯作者） 人环状ＲNA- ** 与肝细胞脂肪变性的相关性及其机制研究 胃肠病学和肝病学杂志 2017 26(6):713-717
Pan Q, Chen MM, Zhang RN, Wang YQ, Zheng RD, Mi YQ, Liu WB, Shen F, Su Q, Fan JG PNPLA3 rs** Predisposes Chronic Hepatitis B to Hepatic Steatosis but Improves Insulin Resistance and Glucose Metabolism J Diabetes Res 2017 2017:**
Zhou D, Pan Q （共同第一作者）, Shen F, Cao HX, Ding WJ, Chen YW, Fan JG Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota Sci Rep 2017 7(1):1529
Guo XY, He CX, Wang YQ, Sun C, Li GM, Su Q, Pan Q （通讯作者）, Fan JG Circular RNA Profiling and Bioinformatic Modeling Identify Its Regulatory Role in Hepatic Steatosis Biomed Res Int 2017 2017:**
Cao Y, Pan Q （共同第一作者）, Cai W, Shen F, Chen GY, Xu LM, Fan JG. Modulation of Gut Microbiota by Berberine Improves Steatohepatitis in High-Fat Diet-Fed BALB/C Mice. Arch Iran Med 2016 19(3):197-203
Zhang RN, Zheng RD, Mi YQ, Zhou D, Shen F, Chen GY, Zhu CY, Pan Q （通讯作者）, Fan JG. APOC3 rs** Is Associated with the Hepatic Steatosis Independently of PNPLA3 rs738409 in Chinese Han Patients with Nonalcoholic Fatty Liver Diseases. Dig Dis Sci 2016 61(8):2284-93
Pan Q （通讯作者）,Sang Y, Chao S, Li G, Wang Y KCNQ1 A340E impairs electrolyte homeostasis independently of the renin-angiotensin-aldosterone system in mice Genet Mol Res 2016 15(3). doi: 10.4238
Pan Q, Zhang RN, Wang YQ, Zheng RD, Mi YQ, Liu WB, Shen F, Chen GY, Lu JF, Zhu CY, Zhang SY, Chen YM, Sun WL, Fan JG. Linked polymorphisms of PNPLA3 confer susceptibility to nonalcoholic steatohepatitis and decreased viral load in chronic hepatitis B World J Gastroenterol 2015 21(28):8605-8614
Qin Pan, Yu-Qin Wang, Guang-Ming Li, Xiao-Yan Duan, Jian-Gao Fan Fuzheng Huayu Recipe Ameliorates Liver Fibrosis by Restoring Balance between Epithelial-to-Mesenchymal Transition and Mesenchymal-to-Epithelial Transition in Hepatic Stellate Cells Biomed Res Int 2015 2015: 935903
Pan Q, Guo C, Sun C, Fan J, Fang C Integrative analysis of the transcriptome and targetome identifies the regulatory network of miR-16: An inhibitory role against the activation of hepatic stellate cells Biomed Mater Eng 2014 246(38):637-1
Guo CJ, Pan Q （共同第一作者）, Xiong H, Qiao YQ, Bian ZL, Zhong W, Sheng L, Li H, Shen L, Hua J, Ma X Therapeutic potential of microRNA: a new target to treat intrahepatic portal hypertension Biomed Res Int 2014 2014(797):898-
Duan XY, Pan Q （共同第一作者）, Yan SY, Ding WJ, Fan JG, Qiao L High-saturate-fat diet delays initiation of diethylnitrosamine-induced hepatocellular carcinoma BMC Gastroenterol 2014 141(95):-
Guo CJ, Pan Q （共同第一作者）, Xiong H, Qiao YQ, Bian ZL, Zhong W, Sheng L, Li H, Shen L, Hua J, Ma X, Fang JY Dynamic expression of miR-126* and its effects on proliferation and contraction of hepatic stellate cells FEBS Lett 2013 587(23):3792-801
Zhang Z, Pan Q （共同第一作者）, Duan XY, Liu Q, Mo GY, Rao GR, Fan JG Fatty liver reduces hepatitis B virus replication in a genotype B hepatitis B virus transgenic mice model J Gastroenterol Hepatol 2012 271(2):1858-64
Pan Q, Ma J, Zhou Q, Li J, Tang Y, Liu Y, Yang Y, Xiao J, Peng L, Li P, Liang D, Zhang H, Chen YH KCNQ1 loss-of-function mutation impairs gastric acid secretion in mice Mol Biol Rep 2010 373(1):329-33
Guo CJ, Pan Q （共同第一作者）, Cheng T, Jiang B, Chen GY, Li DG Changes in microRNAs associated with hepatic stellate cell activation status identify signaling pathways FEBS J 2009 276(18):516-376
Pan Q, Xu WJ, Tang YQ, Yang Y, Ma J, Zhang ZM, Liu Y, Zhou QS, Peng LY, Li PJ, Liang DD, Chen HZ, Li J, Xiao JJ, Zhang J, Chen YH Unique histological features of the left atrial posterior wall J Int Med Res 2009 372(3):929-
Guo CJ, Pan Q （共同第一作者）, Li DG, Sun H, Liu BW MiR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: An essential role for apoptosis J Hepatol 2009 504(7):667-8
Guo CJ, Pan Q （共同第一作者）, Jiang B, Chen GY, Li DG Effects of upregulated expression of microRNA-16 on biological properties of culture-activated hepatic stellate cells Apoptosis 2009 141(11):331-40
He Y, Pan Q （共同第一作者）, Li J, Chen H, Zhou Q, Hong K, Brugada R, Perez GJ, Brugada P Kir2.3 knock-down decreases IK1 current in neonatal rat cardiomyocytes FEBS Lett 2008 582(15):233-842
Liang L, Pan Q （共同第一作者）, Liu Y, Chen H, Li J, Brugada R, Brugada P, Hong K, Perez GJ, Zhao C, Qi J, Zhang Y, Peng L, Li L High sensitivity of the sheep pulmonary vein antrum to acetylcholine stimulation J Appl Physiol 2008 105(1):293-8
Pan Q, He Y, Zhang Z, Liu Y, Zhou Q, Li J, Li P, Liang L, Zhao C, Qi J, Peng L, Chen YH Spatial heterogeneity of muscarinic type 2 receptors in the atrium Int J Cardiol 2008 127(3):427-9