导师姓名： 李旌 专业代码： 100212
性别： 女 专业名称： 眼科学
培养单位： 附属新华医院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师：
联系方式： lj_xinhua@126.com
邮编： 邮箱地址： lj.xinhua@gmail.com

研究方向 (点击浏览详细信息)
炎症反应在眼内病变发生中的作用，眼底疾病的小鼠模型

社会任职
中华医学会眼科分会眼免疫学组委员
中国老年保健医学研究会委员
上海医学会眼科分会视觉研究学组委员
中国医师协会眼科医师分会葡萄膜炎与免疫专业委员会委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
2018YFA** 遗传性钙磷钙磷代谢障碍疾病遗传资源库建立与新致病基因克隆及突变基因谱的构建 科技部国家重点研发计划 2019-09~2024-08 100万元 课题参与人
** 棕榈酸酰基转移酶DHHC16对视网膜双极细胞功能的影响 国家自然科学基金委员会 2019-01~2022-11 57万元 课题负责人
** 虹膜及睫状体上皮细胞在非感染性前葡萄膜炎发病中的作用 国家自然科学基金委员会 2016-01~2019-12 51万元 课题负责人
** zfDHHC16介导的蛋白质棕榈酰化修饰对小鼠眼睛发育和视网膜功能的影响 国家自然科学基金委员会 2014-01~2017-12 70万元 课题负责人
以蛋白质棕榈酰化酶基因敲除小鼠为模型的眼睛发育调控的研究 上海市科委 2012-11~2014-09 25万元 课题负责人
2012CB966901 体内间充质干细胞自我更新、分化及其调控相关组织干细胞的机制研究 科技部 2012-01~2016-12 75万元 子课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Jing Li,Jiaqi He,Xiang Zhang,Jiakai Li,Peiquan Zhao,Ping Fei TSP1 ameliorates age-related macular degeneration by regulating the STAT3-iNOS signaling pathway Experimental Cell Research 2020 388(1)
Huang Y, Shi C, Li J （通讯作者） The protective effect of zeaxanthin on human limbal and conjunctival epithelial cells against UV-induced cell death and oxidative stress Int J Ophthalmol 2019 12(3):369-374
Wu Z, Wu H, Md S, Yu G, Habib SL, Li B, Li J （通讯作者） Tsc1 ablation in Prx1 and Osterix lineages causes renal cystogenesis in mouse. Sci Rep 2019 9(1):837
Jia-Kai Li,Yian Li,Xiang Zhang,Chun-Li Chen,Yu-Qing Rao,Ping Fei,Qi Zhang,Peiquan Zhao,Jing Li （通讯作者） Spectrum of Variants in 389 Chinese Probands With Familial Exudative Vitreoretinopathy Invest Ophthalmol Vis Sci 2018 59(13):5368–5381
Yan Zheng, Yu-Qing Rao, Jia-Kai Li, Yue Huang, Peiquan Zhao, Jing Li （通讯作者） Age-related pro-inflammatory and pro-angiogenic changes in human aqueous humor International Journal of Ophthalmology 2018 11(2):196-200
Biswas S, Li P, Wu H, Shafiquzzaman M, Murakami S, Schneider MD, Mishina Y, Li B, Li J （通讯作者） BMPRIA is required for osteogenic differentiation and RANKL expression in adult bone marrow mesenchymal stromal cells Sci Rep 2018 8(1):8475
FENG Yanqing, WANG Xiangning, WANG Fang, LIU Rongming, CHEN Lu1, WU Shuqin, YANG Xia, CHEN Miaoying, RAO Yu-Qing, LI Jing （通讯作者） The prevalence of ocular allergy and comorbidities in Chinese school children in Shanghai BioMed Research International 2017 2017(1):1-11
Zhongcan Chen, Zhen Cao, Wei Zhang, Minxia Gu, Zhi Dong Zhou,Baojie Li, Jing Li, Eng King Tan,Li Zeng LRRK2 interacts with ATM and regulates Mdm2–p53 cell proliferation axis in response to genotoxic stress Human Molecular Genetics 2017 26(22):4494-4505
Cao N, Li JK, Rao YQ, Liu H, Wu J, Li B, Zhao P, Zeng L, Li J (李旌) （通讯作者） A potential role for protein palmitoylation and zDHHC16 in DNA damage response BMC Molecular Biology 2016 17(1):12
Li JK, Fei P, Li Y, Huang QJ, Zhang Q, Zhang X, Rao YQ, Li J（李旌） （通讯作者）, Zhao P Identification of novel KIF11 mutations in patients with familial exudative vitreoretinopathy and a phenotypic analysis Scientific Reports 2016 23(6):26564
Fei P,Zhu X,Jiang Z,Ma S,Li J(李旌）,Zhang Q,Zhou Y,Xu Y,Tai Z,Zhang L,Huang L,Yang Z,Zhao P,Zhu X Identification and functional analysis of novel FZD4 mutations in Han Chinese with familial exudative vitreoretinopathy Scientific Reports 2015 5:16120
Tielin Zhou,Jing Li(李旌） （共同第一作者）,Peiquan Zhao,Huijuan Liu,Deyong Jia,Hao Jia,Lin He,Yong Cang,Sharon Boast,Yi-Han Chen, Hélène Thibault, Marielle Scherrer-Crosbie, Stephen P. Goff,Baojie Li Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy Proc Natl Acad Sci U S A 2015 112（51）：15666-71
Liyan Chen,Jing Li（李旌） （共同第一作者）,Tiannan Guo,Sujoy Ghosh,Siew Kwan Koh, Dechao Tian,Liang Zhang,Deyong Jia,Roger W. Beuerman,Ruedi Aebersold,Eric Chun Yong Chan,Lei Zhou Global Metabonomic and Proteomic Analysis of Human Conjunctival Epithelial Cells (IOBA-NHC) in Response to Hyperosmotic Stress Journal of Proteome Research 2015 14:3982-3995
Li Jing（李旌）,Setiawan S., Wu H., Beuerman R.W.,Zhao P. Regulation of Toll-like receptor expression in human conjunctival epithelial cells Mediators of Inflammation 2014 2014:493596-9
Ping Fei, Qi Zhang, Luling Huang, Yu Xu, Xiong Zhu, Zhengfu Tai, Bo Gong, Shi Ma, Quanyao Yao, Jing Li(李旌）, Peiquan Zhao, Zhenglin Yang Identification of two novel LRP5 mutations in families with familial exudative vitreoretinopathy Molecular Vision 2014 20:395-409
Fei P, Zhang Q, Li Jing（李旌）, Zhao P Clinical characteristics and treatment of 22 eyes of morning glory syndrome associated with persistent hyperplastic primary vitreous Br J Ophthalmol. 2013 97(10):1262-7
Liu H, Jia D, Li A, Chau J, He D, Ruan X, Liu F, Li Jing（李旌）, He L, Li B. p53 regulates neural stem cell proliferation and differentitation via BMP-Smad1 signaling and id1 Stem Cells Dev. 2013 22(6):913-27
Lili Li, Jianhe Wang, Jenny Fung Ling Chau, Huijuan Liu, Baojie Li, Aijun Hao, Jing Li（李旌） （通讯作者） Smad1 stabilization and delocalization in response to the blockade of BMP activity Cell Mol Biol Lett. 2013 18(3):340-54
Chui Ming Gemmy Cheung, Maya Vania, MarcusAng, Soon Phaik Chee, Jing Li（李旌） （通讯作者） Comparision of aqueous humor cytokine and chemokine levels in diabetic patients with and without retinopathy Molecular Vision 2012 18:830-837
Jocelyn Chua, Maya Vania, Chui Ming Gemmy Cheung, Marcus Ang, Soon Phaik Chee, Henry Yang, Jing Li（李旌） （通讯作者）, Tina T. Wong Expresssion profile of inflammatory cytokines in aqueous from glaucomatous eyes Molecular Vision 2012 18:431-438
Jing Li（李旌） （共同第一作者）, Marcus Ang, Chui Ming Gemmy Cheung, Maya Vania, Anita Sook Yee Chan, Samanthila Waduthantri, Henry Yang, Soon Phaik Chee Aqueous Cytokine Changes Associated with Posner- Schlossman Syndrome with and without Human Cytomegalovirus PLosOne 2012 7(9):e44453
Marcus Ang, Gemmy Cheung, Maya Vania, Jinmiao Chen, Henry Yang, Jing Li（李旌） （通讯作者）, Soon-Phaik Chee. Aqueous cytokine and chemokine analysis in uveitis associated with tuberculosis Molecular Vision 2012 18: 565-573
Li Jing（李旌） （通讯作者）, Zhou Lei and Beuerman Roger W Defensins: Key Molecules in Ocular Surface Protection Current Immunology Reviews 2011 7(3):295-307
Jing Li （通讯作者）,Andri K. Riau,Melina Setiawan,Jodhbir S. Mehta,Seng-Ei Ti, Louis Tong,Donald T.H. Tan, Roger W. Beuerman S100A expression in normal corneal-limbal epithelial cells and ocular surface squamous cell carcinoma tissue Molecular Vision 2011 17:2263-2271
Li Jing（李旌） （共同第一作者）, Zhu Hong Yuan, Beuerman Roger W Human defensins, HNP1, HBD2 and HBD3, stimulate specific cytokines in conjunctival epithelial cells Invest. Ophthalmol. Vis. Sci. 2009 50(2):644-653
Liu Souping*., Zhou Lei.*, Li Jing（李旌）* （共同第一作者）, Suresh A., Verma C., Foo, Y.H., Yap E. P.H., Tan D., Beuerman R.W. Linear analogues of human ?-defensin 3: concepts for design of antimicrobial peptides with reduced cytotoxicity to mammalian cells ChemBioChem 2008 9:964-973
Liu Shaohui.*, Li Jing（李旌）.* （共同第一作者）, Tan Donald, Beuerman Roger W Expression and function of muscarinic receptor subtypes in human corneal and conjunctival cells Invest. Ophthalmol. Vis. Sci. 2007 48(7):2987-96
Li Jing（李旌） （共同第一作者）, Shen Jiangbo., Beuerman Roger W Expression of Toll-like receptors in human limbal and conjunctival epithelial cells Mol. Vis. 2007 13:813-822