导师姓名： 韩邦旻 专业代码： 100210
性别： 男 专业名称： 外科学
培养单位： 附属第一人民医院 三级学科/
专业领域： 泌尿外
导师类型： 博士生导师 专业学位导师： 兼
联系方式： 上海市虹口区海宁路100号市一医院泌尿外科中心hanbm@163.com
邮编： 200080 邮箱地址： hanbm@163.com

研究方向 (点击浏览详细信息)
基质细胞在前列腺疾病发病进展中的作用

社会任职
中国医师协会男科医师分会常委兼副总干事长，前列腺疾病咨询与管理委员会秘书长
《山东大学学报医学版》编委，《中华诊断学杂志》通讯编委，统计源期刊《中华临床医师》审稿专家和特约编辑
亚洲男科学会副秘书长，世界华人医师协会男科分会秘书长
中华医学会泌尿外科分会国际交流委员会委员、尿控学组委员
上海市医学会男科学分会委员兼秘书、前列腺疾病学组副组长
中国医师协会内镜分会委员、整合分会泌尿外科专业委员会常委

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
** 去势条件下CAF的异常增殖与活化促进CRPC形成及机制研究 国自然面上项目 2018-01~2021-12 50万元 课题负责人
** 雄激素受体在膀胱癌细胞和肿瘤相关巨噬细胞间的介导作 国自然面上项目 2014-01~2017-12 62万元 课题负责人
** 前列腺外周带基质细胞的老龄化生长特征及其对上皮细胞的影响 国家自然科学基金 2011-01~2013-12 28万元 课题负责人
10ZR** 雄激素受体对膀胱癌细胞侵袭转移的影响 上海市自然科学基金 2010-04~2012-04 10万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Yang BY, Deng GY, Zhao RZ, Dai CY, Jiang CY, Wang XJ, Jing YF, Liu XJ, Xia SJ, Han BM. （通讯作者） Porous Se@SiO2 nanosphere-coated catheter accelerates prostatic urethra wound healing by modulating macrophage polarization through reactive oxygen species-NF-κB pathway inhibition. Acta Biomater. 2019 Feb 10
Deng Z, Shi F, Zhou Z, Sun F, Sun MH, Sun Q, Chen L, Li D, Jiang CY, Zhao RZ, Cui D, Wang XJ, Jing YF, Xia SJ, Han BM. （通讯作者） M1 macrophage mediated increased reactive oxygen species (ROS) influence wound healing via the MAPK signaling in vitro and in vivo. Toxicol Appl Pharmacol. 2019 1;366:83-95.
Zhao S, Jiang JT, Li D, Zhu YP, Xia SJ, Han BM. （通讯作者） Maternal exposure to di-n-butyl phthalate promotes Snail1-mediated epithelial-mesenchymal transition of renal tubular epithelial cells via upregulation of TGF-β1 during renal fibrosis in rat offspring. Ecotoxicol Environ Saf. 2019 169:266-272
Yuan R, Boyu Y, Fujun Z, Chengyi J, Yifeng J, Xiaohai W, Di C, Shujie X, Bangmin H. （通讯作者） Transurethral thulium laser enucleation versus resection of the prostate for treating benign prostatic hyperplasia: a retrospective study. Lasers Med Sci. 2019 34(2):329-334.
Zhao R （通讯作者）, Wang X, Jiang C, Shi F, Zhu Y, Yang B, Zhuo J, Jing Y, Luo G, Xia S, Han B. Finasteride accelerates prostate wound healing after thulium laser resection through DHT and AR signalling Cell Proliferation 2018 51(3):e12415.
Zhao S, Li D, Bei XY, Zhu YP, Sun WL, Shen C, Wood K, Han BM （通讯作者）, Jiang JT. Maternal exposure to di-n-butyl phthalate (DBP) promotes epithelial-mesenchymal transition via regulation of autophagy in uroepithelial cell. Toxicology. 2018 06-407:114-122.
蒿魁元,赵圣,张宇,崔迪,荆翌峰,夏术阶,韩邦旻 （通讯作者） 雄激素阻断对膀胱癌UM-UC-3细胞自噬与凋亡的影响 山东大学学报（医学版） 2018 56(03):41-47.
Deng Z, Sun M, Zhu Y, Zhuo J, Zhao F, Xia S, Han B （通讯作者）, Herrmann TRW. Thulium laser VapoResection of the prostate versus traditional transurethral resection of the prostate or transurethral plasmakinetic resection of prostate for benign prostatic obstruction: a systematic review and meta-analysis. World J Urol. 2018 36(9):1355-1364.
Sun Q, Guo W, Cui D, Wang X, Ruan Y, Zhao F, Xia S, Han B （通讯作者）, Jing Y. Thulium laser enucleation versus thulium laser resection of the prostate for prevention of bladder neck contracture in a small prostate: a prospective randomized trial. World J Urol. 2018 sep7
Hao KY ,Zhao S,Cui D,Zhang Y, Jiang CY , Jing YF,Xia SJ,Han BM （通讯作者） Androgen receptor antagonist bicalutamide induces autophagy and apoptosis via ULK2 upregulation in human bladder cancer cells International Journal of Clinical and Experimental Pathology 2017 10(6): 7603-7615
王小海,徐东亮,赵福军,王兴杰,夏术阶,韩邦旻 （通讯作者） 慢性前列腺炎与勃起功能障碍的相关性研究 泌尿外科杂志（电子版） 2016 8(04):23-26.
Qingsong Zou, Di Cui, Shengjie Liang, Shujie Xia, Yifeng Jing , Bangmin Han （通讯作者） Aging up-regulates ARA55 in stromal cells, inducing androgen-mediated prostate cancer cell proliferation and migration journal of molecular histology 2016 47(3):305-15
Gao Y, Jiang S,Cui D, Mao S, Hao K,Zhao W, Ruan Y,Jiang Q,Xia S,Han BM （通讯作者）, Low Serum Testosterone Predicts Upgrading and Upstaging of Prostate Cancer after Radical Prostatectomy Asian Journal of Andrology 2016 18(4):639-43
邹青松,梁胜杰,高原,毛师魁,蒿魁元,夏术阶,韩邦旻 （通讯作者） 不同年龄段前列腺外周带基质细胞AR活性差异对前列腺上皮细胞增殖的影响 中国男科学杂志 2015 2015(3)
Shengjie Liang,Qingsong Zou,Bangmin Han （通讯作者）, et al. Intra-Arterial Chemotherapy for Muscle-Invasive Bladder Cancer Following Transurethral Resection Urol Int 2015 94(4):406-11
高原,韩邦旻,赵炜,阮渊,蒋琪,赵福军,孙晓文,邹青松,姜辰一,蒿魁元,毛师魁,夏术阶 腹腔镜下根治性前列腺切除术疗效分析 中华泌尿外科杂志 2015 36(08): 607-610
高原,邹青松,毛师魁,蒿魁元,夏术阶,韩邦旻 （通讯作者） 血清睾酮水平和前列腺癌病理分级及术后病理升级的相关性研究 临床泌尿外科杂志 2015 30(10):910-912
Jing YF , Cui D , Guo WH , Jiang JT , Jiang B , Lu YY, Zhao W , Wang XH,Jiang Q, Han BM （通讯作者）, Shujie Xia Activated androgen receptor promotes bladder cancer metastasis via Slug mediated epithelial-mesenchymal transition Cancer letters 2014 348(1-2):135-45
高原,韩邦旻 （通讯作者）,梁胜杰等 前列腺癌根治术后是否立即辅助内分泌治疗的META分析 国际泌尿系统杂志 2014 34(6):861-864
Han BM,Liang SJ, Jing YF, Cui D,An X, Zou QS , Wei HB, Xia SJ Organ preservation for muscle-invasive bladder cancer by preoperative intra-arterial chemotherapy and transurethral Resection Med Oncol 2014 31(4):912
Li EH*, Han BM* （共同第一作者）, Sun WL, Liang SJ, Xia SJ, Jiang JT Expression of Wnt5a during development of anorectal malformations in a rat model of prenatal exposure to di(n-butyl) phthalate Toxicol Mech Methods 2014 24(7):455-60
高原,韩邦旻 （通讯作者）,梁胜杰等 前列腺癌根治术后是否立即辅助内分泌治疗的META分析 国际泌尿系统杂志 2014 34(6):861-864
Lu YY, Jiang B, Zhao FJ, Cui D, Jiang Q, Yu JJ,Li EH,Wang XH,Han BM* （通讯作者）,Xia SJ* Androgen receptors expressed by prostatic stromal cells obtained from younger versus older males exhibit opposite roles in prostate cancer progression Asian J Andrology 2013 15(5):672-8
Bangmin Han,Di Cui,Yifeng Jing ,Yan Hong ,Shujie Xia Estrogen receptor  (ER) is a novel prognostic markerof recurrence survival in non-muscle-invasive bladder cancerpotentially by inhibiting cadherin switch world journal of Urology 2012 30:861–867
Jiang Q, Han BM, Zhao FJ, Hong Y, Xia SJ* The differential effects of prostate stromal cells derived from different zones on prostate cancer epithelial cells under the action of sex hormones Asian J Andrology 2011 13(6):798-805
Wang XH, Zhao FJ, Han BM, Jiang Q, Wang YC, Wu JH, Tang YQ, Zhang YP, Xia SJ* Primary stromal cells isolated from human various histological/pathological prostate have different phenotypes and tumor promotion role Chin Med J (Engl) 2011 124(11):1700-7
Wang YC, Yu SQ, Wang XH, Han BM, Zhao FJ, Zhu GH, Hong Y, Xia SJ* Differences in phenotype and gene expression of prostate stromal cells from patients of varying ages and their influence on tumour formation by prostate epithelial cells Asian J Andrology 2011 13(5):732-41
韩邦旻,吴吉涛,崔迪,荆翌峰,赵福军,洪艳,夏术阶 电穿孔法介导雄激素受体基因沉默抑制裸鼠膀胱癌移植瘤生长的研究 中华实验外科杂志 2011 28（6）:844–846
Ji-Tao Wu, Bang-Min Han （通讯作者）, Sheng-Qiang Yu, Hui-Ping Wang, and Shu-Jie Xia Androgen Receptor Is a PotentialTherapeutic Target for Bladder Cancer Urology 2010 75（4）：820-827
Zhao FJ, Han BM, Yu SQ, Xia SJ* Tumor formation of prostate cancer cells influenced by stromal cells from the transitional or peripheral zones of the normal prostate Asian J Andrology 2009 11(2):176-82
韩邦旻,夏术阶,王精兵,鲁军,凡杰,孙晓文,刘海涛 保留膀胱的手术切除联合髂内动脉化疗治疗局部浸润性膀胱癌 临床泌尿外科杂志 2009 24(4)：249-250
Yu SQ, Han BM, Shao Y, Wu JT, Zhao FJ, Liu HT, Sun XW, Tang YQ, Xia SJ* Androgen receptor functioned as a suppressor in the prostate cancer cell line PC3 in vitro and in vivo Chin Med J (Engl) 2009 122(22):2779-83
Tang YQ, Han BM, Yao XQ, Hong Y, Wang Y, Zhao FJ, Yu SQ, Sun XW, Xia SJ* Chimeric molecules facilitate the degradation of androgen receptors and repress the growth of LNCaP cells Asian J Andrology 2009 11(1):119-26
韩邦旻,杨明山,路光中,朱江,鲁军,凡杰,夏术阶 阴茎疣状癌的临床诊断和治疗 中华肿瘤防治杂志 2008 15（9）：709-710
Li R, Guo Y, Han BM, Yan X, Utleg AG, Li W, Tu LC, Wang J, Hood L, Xia SJ*, Lin B* Proteomics cataloging analysis of human expressed prostatic secretions reveals rich source of biomarker candidates Proteomics Clin Appl 2008 2(4):543-555