导师姓名： 赵玉武 专业代码： 100204
性别： 男 专业名称： 神经病学
培养单位： 附属第六人民医院 三级学科/
专业领域：
导师类型： 博士生导师 专业学位导师： 兼
联系方式： zhaoyuwu2005@126.com
邮编： 200233 邮箱地址： zhaoyuwu2005@126.com

研究方向 (点击浏览详细信息)
脑血管病、糖尿病相关神经系统并发症

社会任职
上海市卫生系统高评委
上海市中西医结合学会神经内科分会副主委
中国免疫学会神经免疫分会委员
上海市医师协会神经内科医师分会副会长
上海市医学会慢病管理专科分会副主委
中华医学会神经病学分会委员
中国医师协会中西医结合医师分会神经病学专家委员会常委
上海市医学会慢病管理分会副主委
中华医学会神经病学分会神经免疫学组委员
上海市中西医结合学会脑心同治专业委员副主委
中国卒中学会免疫分会副主委
中国卒中学会移动医疗分会委员
上海市医学会神经内科分会副主委
中华医学会神经病学分会委员

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
消退素D2的神经保护作用研究 国家自然科学基金，国际合作 2018-01~2020-12 50万元 课题负责人
** 消退素D2在糖尿病缺血性脑卒中发病中的作用及其靶向治疗研究 国家自然科学基金，面上项目 2017-01~2021-12 65万元 课题负责人
院级-081 糖尿病性神经系统并发症的诊治 医院优势特色专业 2014-12~2017-12 46万元 课题负责人
** 大鼠低血糖后脑水肿的分子机制研究 国家自然科学基金 2013-01~2016-12 85万元 课题负责人
** 低血糖后血糖升高速度对大鼠低血糖性脑损害的影响及其机制的研究 国家自然科学基金 2010-01~2012-12 32万元 课题负责人
C090301 低血糖后血糖升高速度对大鼠低血糖性脑损伤的影响及其机制的研究 国家自然基金，面上项目 2010-01~2012-12 32万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
Zhao Fei, Deng Jiangshan, Xu Xiaofeng, Cao Fengya, Lu Kaili, Li Dawei, Cheng Xiaojuan, Zhao Yuwu# （通讯作者） Aquaporin-4 deletion ameliorates hypoglycemia-induced BBB permeability by inhibiting inflammatory responses Journal of Neuroinflammation 2018 15(1):157
Zhang Ting, Wang Hongmei, Li Q, Fu Jianliang, Huang Jiankang, Zhao Yuwu# （通讯作者） MALAT1 activates the p53 signaling pathway by regulating MDM2 to rromote ischemic stroke. Cell Physiol Biochem. 2018 50:2216-2228.
Zhang Bin, Xu XF, Chu Xiuli, Xu YZ, Zhao Yuwu# （通讯作者） Protective effects of angiopoietin-like 4 on the blood-brain barrier in acute ischemic stroke treated with thrombolysis in mice. Neuroscience Letters 2017 645(3):113-120
Xue Lixia, Chen Hao, Lu Kaili, Huang Jiankang, Duan Hao, Zhao Yuwu# （通讯作者） Clinical significance of changes in serum neuroglobin and HIF-1 alpha. concentrations during the early-phase of acute ischemic stroke. Journal of the Neurological Sciences. 2017 375:52-57.
Wang Hongmei, Zhang Ting, Huang Jiankang, Xiang JY, Chen JJ, Fu Jianliang, Zhao Yuwu# （通讯作者） Edaravone Attenuates the Proinflammatory Response in Amyloid-β-Treated Microglia by Inhibiting NLRP3 Inflammasome-Mediated IL-1β Secretion. Cell Physiol Biochem 2017 43(3):1113-1125
Lixia Xue 1 ,Hao Chen2, Ting Zhang1 , Jingjiong Chen1 , Zhi Geng1 , Yuwu Zhao （通讯作者） Changes in serum vascular endothelial growth factor and endostatin concentrations associated with circulating endothelial progenitor cells after acute ischemic stroke Metab Brain Dis 2017 32:641–648
Xu Y, Wang Q, Li D, Wu Z, Li D, Lu K, Zhao Y* （通讯作者） Protective effect of lithium chloride against hypoglycemia-induced apoptosis in neuronal PC12 cell Neuroscience 2016 330: 100-108.
Xu Y, Wang Q, Liu Y, Cui R, Lu K, Zhao Y* （通讯作者） Association between Helicobacter pylori infection and carotid atherosclerosis in patients with vascular dementia J Neurol Sci 2016 362: 73-77
Xu Y, Wang Q, Liu Y, Cui R, Zhao Y* （通讯作者） Is Helicobacter pylori infection a critical risk factor for vascular dementia? Int J Neurosci 2016 126(10): 899-903
Xu X, Zhang B, Lu K, Deng J, Zhao F, Zhao B Q, Zhao Y* （通讯作者） Prevention of Hippocampal Neuronal Damage and Cognitive Function Deficits in Vascular Dementia by Dextromethorphan Mol Neurobiol 2016 53(5): 3494-3502
Lu K, Xu X, Cui S, Wang F, Zhang B, Zhao Y* （通讯作者） Serum neuron specific enolase level as a predictor of prognosis in acute ischemic stroke patients after intravenous thrombolysis J Neurol Sci 2015 359(1-2): 202-206
Xu Yuzhen,Wang Qian,Liu Yunlin,Cui Ruiting,Zhao Yuwu （通讯作者） Is Helicobacter pylori infection a critical risk factor for vascular dementia? International Journal of Neuroscience 2015 pp 1-5
Cheng Xiao-Juan, Gao Yuan, Zhao Yu-Wu （通讯作者）, Cheng Xiao-Dong Sodium Chloride Increases Abeta Levels by Suppressing Abeta Clearance in Cultured Cells PLos One 2015 10(6), p e**
Jiangshan Deng,Fei Zhao,Xiaoyan Yu,Dawei Li,Yuwu Zhao （通讯作者） Identification of the Protective Role of DJ-1 in Hypoglycemic Astrocyte Injury Using Proteomics Journal of proteome research 2015 14(7):2839-48
Fei Zhao,Jiangshan Deng,Xiaoyan Yu,Dawei Li,Hong Shi,Yuwu Zhao （通讯作者） Protective effects of vascular endothelial growth factor in cultured brain endothelial cells against hypoglycemia. Metabolic brain disease 2015 30(4):999-1007
Xiuli Chu,Yuwu Zhao （通讯作者）,Fang Liu,Yajing Mi,Jie Shen,Xiyun Wang, Jianzhi Liu,Weilin Jin Rapidly Raise Blood Sugar Will Aggravate Brain Damage After Severe Hypoglycemia in Rats Cell Biochemistry and Biophysics 2014 69(1):131-9
Jiangshan Deng,Fei Zhao,Xiaoyan Yu,Yuwu Zhao （通讯作者）,Dawei Li,Hong Shi,Yongning Sun Expression of aquaporin 4 and breakdown of the blood-brain barrier after hypoglycemia-induced brain edema in rats PLoS One 2014 29;9(9):e107022
*Xiang Jing-Yan,Zhang Yu-Hua,Tan Zhi-Rong, Huang Jie, Zhao Yu-Wu （通讯作者） Guillain-Barre Syndrome Associated with Japanese Encephalitis Virus Infection in China Viral Immunology 2014 27(8), pp 418-420
Xiao-Er Wei,Yu-Wu Zhao （通讯作者）,Jing Lu, Ming-Hua Li,Wen-Bin Li,Ya-Jun Zhou,Yue-Hua Li Timing of recanalization and outcome in ischemic-stroke patients treated with recombinant tissue plasminogen activator Acta Radiologica 2014 0(0), pp 1-8
Jiawen Yuan, Yuwu Zhao （通讯作者） Evolutionary aspects of the synuclein super-family and sub-families based on large-scale phylogenetic and group-discrimination analysis Biochem Biophys Res Commun 2013 441(2):308-17
Xiang J, Zhao Y （通讯作者）, Chen J, Zhou J. Expression of basic fibroblast growth factor, protein kinase C and members of the apoptotic pathway in skeletal muscle of streptozotocin-induced diabetic rats Tissue Cell 2013 46(1):1-8
LIU Fang, LIU Jiang, ZHENG Tai-shan, WANG Chen, PAN Xiao-ping, LU Huijuan ,ZHAO Yu-wu （通讯作者） The -1123G>C Variant of PTPN22 Gene Promoter is Associated with Latent Autoimmune Diabetes in Adult Chinese Hans Cell Biochemistry and Biophysics 2012 62(2):273-279
Zhongsen Qu,Zongxian Jiao,Xiaojiang Sun,Yuwu Zhao,Jinpeng Ren,Guogang Xu Effects of streptozotocin-induced diabetes on tau phosphorylation in the rat brain Brain Research 2011 1383:300-6
WANG Jin-wu, HOU Chun-lin, NI Wei-feng, RUI Bi-yu, GUO Shang-chun, ZHAO Yu-wu （通讯作者）,ZHENG Xian-you and DAI Ke-rong An experimental study of artificial murine bladder reflex arc established by abdominal reflex Chinese Medical Journal 2011 124(3):413-418
ZHANG Tian-ling, ZHAO Yu-wu # （通讯作者）, LIU Xue-yuan and DING Su-ju Effects of L-lysine monohydrochloride on insulin and blood glucose levels in spinal cord injured rats Chin Med J 2010 123(6):722-725
Haitao Lu1, Jungong Zhao , Minghua Li, Yingsheng Cheng, Yongdong Li, Xiaofang You1, Yuwu Zhao （通讯作者） Microvessel changes after post-ischemic benign and malignant hyperemia: experimental study in rats BMC Neurology 2010 10(24):1-8
HUANG Jing, CHEN Yu-juan, BIAN Wei-hong, YU Jing, ZHAO Yu-wu # （通讯作者）,LIU Xue-yuan Unilateral amyloid-β25-35 injection into the rat amygdala increases the expressions of aberrant tau phosphorylation kinases Chin Med J 2010 123(10):1311-1314
Yuwu Zhao # （通讯作者）,Xueyuan Liu,Aiyong Yu,Yajun Zhou,Bangjian Liu Diabetes-Related Alteration of Occludin Expression in Rat Blood-Spinal Cord Barrier Cell Biochem Biophys 2010 58(3):141-145
REN Jin-peng, ZHAO Yu-wu # （通讯作者）,SUN Xiao-jiang Toxic influence of chronic oral administration of paraquat on nigrostriatal dopaminergic neurons in C57BL/6 mice Chin Med J 2009 122(19):2366-2371