导师姓名： 霍炎 专业代码： 100700
性别： 男 专业名称： 药学
培养单位： 附属第六人民医院 三级学科/
专业领域：
导师类型： 硕士生导师 专业学位导师：
联系方式： 上海市宜山路600号11号楼
邮编： 200233 邮箱地址： huoyan@sjtu.edu.cn

研究方向 (点击浏览详细信息)
中药心血管药理 中药药效物质基础

社会任职
上海市植物学会药用植物委员会 理事

科研项目 项目编号项目名称课题来源起止年月批准经费承担职责
YG2014MS21 天然Nur77激动剂金丝桃苷及其结构类似物抑制血管平滑肌细胞增殖作用机制研究 上海交通大学医工交叉基金 2015-01~2017-12 15万元 课题负责人
14ZR** 金丝桃苷调控Nur77表达抑制血管平滑肌细胞增殖机制研究 上海市科委 2014-07~2017-06 10万元 课题负责人

学术论文 作者论文标题期刊名出版年卷期页码
冯丹,霍炎 （通讯作者） 孤儿核受体Nur77对哮喘小鼠气道重构的作用研究 中国临床药理学杂志 2019 15:1621-1624
冯丹,霍炎 （通讯作者） 气道平滑肌细胞增殖的分子机制研究进展 医学综述 2019 14:2765-2771
Yang QuanJun, Zhao JR, Hao J, Li Bin, Huo Yan, Han YongLong, Wan LiLi, Li Jie, Huang Jinlu, Lu Jin, Yang GenJin, Guo Cheng Serum and urine metabolomics study reveals a distinct diagnostic model for cancer cachexia J Cachexia Sarcopenia Muscle 2018 9(1):71-85
QuanJun Yang, GenJin Yang, LiLi Wang, YongLong Han, Yan Huo, Jie Li, JinLu Huang, Jin Lu, Run Gun, Cheng Guo Protective Effects of Dexrazoxane against Doxorubicin-Induced Cardiotoxicity: A Metabolomic Study PLoS One 2017 12(1):e**
Quan-Jun Yang, Yan Huo, Yong-Long Han, Li-Li Wan, Jie Li, Jin-Lu Huang, Jin Lu, Peng-Guo Chen, Run Gun, Cheng Guo Selumetinib Attenuates Skeletal Muscle Wasting in Murine Cachexia Model through ERK Inhibition and AKT Activation Mol Cancer Ther 2017 16(2):334-343
Sun XinPeng, Wan LiLi, Yang QuanJun, Huo Yan, Han YongLong, Guo Cheng Scutellarin protects against doxorubicin-induced acute cardiotoxicity and regulates its accumulation in the heart Arch Pharm Res 2017 40(7):875-883.
Chen Peng-Guo, Li Jie, Huo Yan, Lu Jin, Wan Li-Li, Quanjun Yang, Jinlu Huang, Gan Run and Guo Cheng Adenovirus-mediated expression of orphan nuclear receptor NR4A2 targeting hepatic stellate cell attenuates liver fibrosis in rats Scientific Reports 2016 6: 33593
Chen, Pengguo ,Li, Jie,Huo, Yan,Lu, Jin,Wan, Lili,Li, Bin,Gan,Run,Guo, Cheng Orphan nuclear receptor NR4A2 inhibits hepatic stellate cell proliferation through MAPK pathway in liver fibrosis PeerJ 2015 3：e1518-e1518
Qi, Jia ,Yang, Ping,Yi, Bing,Huo, Yan,Chen, Ming,Zhang,Jian,Sun, Jianxin Heat shock protein 90 inhibition by 17-DMAG attenuates abdominal aortic aneurysm formation in mice Am J Physiol Heart Circ Physiol 2015 308（8）:H841-H852
Yang QuanJun ,Yang GenJin,Wan LiLi,Huo Yan,Han YongLong,Lu Jin,Li Jie,Huang JinLu,Guo Cheng Integrated analysis of serum and intact muscle metabonomics identify metabolic profiles of cancer cachexia in a dynamic mouse model RSC Advances 2015 5（112）：92438-92448
Yan Huo, Bing Yi, Ming Chen, Nadan Wang,Pengguo Chen, Cheng Guo*,Jianxin Sun* Induction of Nur77 by Hyperoside Inhibits Vascular Smooth Muscle Cell Proliferation and Neointimal formation. Biochemical Pharmacology 2014 92(4):590-598
Huo Yan, Shi Haiming, Guo Cheng, Li Xiaobo Chemical Constituents of root of Inula helenium Chemistry of Natural Compounds 2012 48(3):522-524
Huo Yan （共同第一作者）, Shi Haiming, Li Weiwei, Wang Mengyue, Li Xiaobo HPLC determination and NMR structural elucidation of sesquiterpene lactones in Inula helenium. Journal of Pharmaceutical and Biomedical Analysis 2010 51(4):942-946
Huo Yan,Shi Haiming,Wang Mengyue,Li Xiaobo. Complete assignments of 1H and 13C NMR spectral data for three sesquiterpenoids from Inula helenium Magnetic Resonance in Chemistry 2008 46(12): 1208-1211
Huo Yan,Shi Haiming,Wang Mengyue,Li Xiaobo Chemical constituents and pharmacological properties of Radix Inulae Pharmazie 2008 63(10): 699-703
Huo Yan, Guo Cheng, Lu Shan, Zhang Qiaoyan, Qin Luping Chemical research of Caragana microphylla seeds Chemistry of Natural Compounds 2007 43(2): 214-215
Huo Yan, Guo Cheng, Zhang Qiaoyan, Chen Wansheng, Zheng Hanchen, RahmanKalid, Qin Luping Antinociceptive activity and chemical composition of constituents Phytomedicine 2007 14(2-3):143-146