许学伟 研究员, 上海交大海洋学院/自然资源部第二海洋研究所 固定电话：
电子邮件：xuxw@sio.org.cn
通讯地址：杭州市保俶北路36号



教育背景 2000.09－2005.06 浙江大学生命科学学院，遗传学博士
1996.09－2000.06 浙江大学生物技术系，本科。

工作经历 2018.10－至今双聘于上海交通大学
2011.12－至今国家海洋局第二海洋研究所，研究员
2008.03－2011.12 国家海洋局第二海洋研究所，副研究员
2005.07－2008.03 浙江大学生命科学学院，博士后/讲师
期间曾在美国海洋生物实验室（Marine Biology Laboratory，2013.04－2014.04）和美国伍兹霍尔海洋研究所（Woods Hole Institution of Oceanography，2017.06-07和09-10）访问交流

研究方向 海洋微生物资源与分类
海洋微生物酶功能结构
深海空间规划与保护

科研项目 1.深海多金属结核与富钴结壳区微生物地理分布比较，国家自然科学基金，2009-2011，负责
2.深海结核结壳区微生物资源挖掘及氧化还原酶资源开发，海洋公益性行业科研专项子课题，2010-2014，负责
3.环境保全参照区和保全参照区建设，大洋专项，2013-2015，负责
4.基于生态基因组学探讨深海多金属结核与钴结核形成机制，国家自然科学基金，2013-2016，负责
5.赤杆菌科微生物分类与演化研究，浙江省自然科学基金****项目，2017-2020，负责
6.基于基因组的赤杆菌科细菌分子系统发育及其分类标准研究，国家自然科学基金，2018-2021，负责

代表性论文专著 近3年发表论文（2016-2018）：
1.Xu L., Wu Y.-H., Zhou P., Cheng H., Liu Q. & Xu X.-W. Investigation of the thermophilic mechanism in the genus Porphyrobacter by comparative genomic analysis. BMC Genomics. 2018, 19: 385. (https://doi.org/10.1186/s12864-018-4789-4)
2.Huang M., Zhou T., Wu Y., Fei H., Wang G., Li Z., Lei Z., Liu Q., Sun C., Lv Z. & Xu X.-W. Characterisation and functional comparison of single-CRD and multidomain containing galectins CgGal-2 and CgGal-3 from oyster Crassostrea gigas. Fish & Shellfish Immun. 2018, 78: 238-247.
3.Wu Y.-H., Yan J., Fang C., Huo Y.-Y., Ma W.-L., Zhang D.-M., Wang C.-S. & Xu X.-W. Gracilimonas amylolytica sp. nov., isolated from deep-sea sediment. Int J Syst Evol Microbiol. 2018, 68:1713-1718.
4.Wu Y.-H., Fang C., Zhou P., Wang C.-S. & Xu X.-W. Complete genome sequence of a heavy metal resistant bacterium Maribacter cobaltidurans B1T, isolated from the deep-sea sediment of the South Atlantic Ocean. Mar Genom. 2018, 39: 19-21.
5.Rong Z., Huo Y.-Y., Jian S.-L., Wu Y.-H. & Xu X.-W. Characterization of a novel alkaline esterase from Altererythrobacter epoxidivorans CGMCC 1.7731T. Prep Biochem Biotech. 2018, 48:113-120.
6.Huo Y.-Y., Jian S.-L., Cheng H., Rong Z., Cui H.-L. & Xu X.-W. Two novel deep-sea sediment metagenome-derived esterases: residue 199 is the determinant of substrate specificity and preference. Microb Cell Fact. 2018, 17:16. (https://doi.org/10.1186/s12934-018-0864-4)
7.Chen X., Chen J., Yan Y., Chen S., Xu X.-W., Zhang H. & Wang H. Quorum sensing inhibitors from marine bacteria Oceanobacillus sp. XC22919. Nat Prod Res, 2018, 12:1-5. (DOI: 10.1080/**.2018.**)
8.Chun J., Oren A., Ventosa A., Christensen H., Arahal D. R., da Costa M. S., Rooney A. P., Hana Y., Xu X.-W., Meyer S. D. & Trujillo M. E. Proposed minimal standards for the use of genome data for the taxonomy of prokaryotes. Int J Syst Evol Microbiol. 2018, 68:461-466.
9.Huang M.-M., Guo L.-L., Wu Y.-H., Lai Q.-L., Shao Z.-Z., Wang C.-S., Wu M. & Xu X.-W. Pseudooceanicola lipolyticus sp. nov., a marine alphaproteobacterium, reclassification of Oceanicola flagellatus as Pseudooceanicola flagellatus comb. nov. and emended description of the genus Pseudooceanicola. Int J Syst Evol Microbiol. 2018, 68: 409-415.
10.Fang C., Wu Y.-H., Xamxidin M., Wang C.-S. & Xu X.-W. Maribacter cobaltidurans sp. nov., a heavy-metal-tolerant bacterium isolated from deep-sea sediment. Int J Syst Evol Microbiol. 2017, 67(12):5261-5267.
11.Guo L.-L., Wu Y.-H., Xu X.-W., Huang C.-J., Xu Y.-Y., Cheng H., Wang C.-S., Wu M. & Xu X.-W. Actibacterium pelagium sp. nov., a novel alphaproteobacterium, and emended description of the genus Actibacterium. Int J Syst Evol Microbiol. 2017, 67(12):5080-5086.
12.Wu Y.-H., Cheng H., Huo Y.-Y., Xu L., Liu Q., Wang C.-S. & Xu X.-W. Complete genome sequence of esterase-producing bacterium Croceicoccus marinus E4A9T. Stand Genomic Sci. 2017, 12:88.
13.Huo Y.-Y., Rong Z., Jian S.-L., Xu C.-D., Li J. & Xu X.-W. A novel halotolerant thermoalkaliphilic esterase from marine bacterium Erythrobacter seohaensis SW135. Front Microbiol. 2017, 8: 2315 (doi: 10.3389/fmicb.2017.02315)
14.Kuang S., Zheng J., Yang H., Li S., Duan S., Shen Y., Ji C., Gan J., Xu X-W. & Li J. Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis. Proc Natl Acad Sci USA. 2017, 114:10642-10647.
15.Huang M., Mu C., Wu Y., Ye Fei., Wang Dan., Sun C., Lv Z., Han B., Wang C. & Xu X.-W. The functional characterization and comparison of two single CRD containing C-type lectins with novel and typical key motifs from Portunus trituberculatus. Fish & Shellfish Immun. 2017, 70:398-407.
16.Liu Y., Lai Q., Xu X.-W., Wu Y.-H., Cheng H., Zhang X.-H., Wang L. & Shao Z. Reclassification of Xuhuaishuia manganoxidans Wang et al. 2015 as a later heterotypic synonym of Brevirhabdus pacifica Wu et al. 2015 and emendation of the species description. Int J Syst Evol Microbiol. 2017, 67: 3095-3098.
17.Wu Y.-H., Cheng H., Huo Y.-Y., Jin X.-B., Wang C.-S. & Xu X.-W. Henriciella pelagia sp. nov., isolated from seawater. Int J Syst Evol Microbiol. 2017. 67(8): 3020-3025.
18.Xu L., Wu Y.-H., Zhou Y.-G., Cheng H., Liu Q., Zhou P., Wu M., Cheng L. & Xu X.-W. Complete genome sequence of Erythrobacter gangjinensis CGMCC 1.15024T with two chromosomes. Mar Genom. 2017, 34:15-18.
19.Cheng H., Wu Y.-H., Huo Y.-Y, Zhou P., Liu Q., Wang C.-S. & Xu X.-W. Complete genome sequence of Altererythrobacter dongtanensis KCTC 22672T, isolated from a tidal flat. Mar Genom. 2017, 34:11-14.
20.Huo Y.-Y., Li S., Huang J., Rong Z., Wang Z., Li Z., Ji R., Kuang S., Cui H.-L., Li J. & Xu X.-W. Crystal structure of Pelagibacterium halotolerans PE8: new insight into its substrate-binding pattern. Sci Rep. 2017, 7: 4422 (DOI:10.1038/s41598-017-04550-7).
21.Wu Y.-H., Cheng H., Xu L., Jin X.-B., Wang C.-S. & Xu X.-W. Physiological and genomic features of a novel violacein-producing bacterium isolated from surface seawater. PLoS ONE. 2017, 12(6): e**.
22.Liu Q., Wu Y.-H., Cheng H., Xu L., Wang C.-S. & Xu X.-W. Complete genome sequence of bacteriochlorophyll-synthesizing bacterium Porphyrobacter neustonensis DSM 9434. Stand Genomic Sci. 2017, 12: 32.
23.Cheng H., Huo Y.-Y., Hu J., Xu X.-W. & Wu M. High quality draft genome sequence of an extremely halophilic archaeon Natrinema altunense strain AJ2T. Stand Genomic Sci. 2017, 12: 25.
24.Shi X.-L., Wu Y.-H., Jin X.-B., Wang C.-S. & Xu X.-W. Alteromonas lipolytica sp. nov., a ploy-beta-hydroxybutyrate-producing bacterium isolated from surface seawater. Int J Syst Evol Microbiol. 2017, 67: 237-242.
25.Xu L., Wu Y.-H., Jian S.-L., Wang C.-S., Wu M., Cheng L. & Xu X.-W. Pseudohongiella nitratireducens sp. nov., isolated from seawater, and emended description of the genus Pseudohongiella. Int J Syst Evol Microbiol. 2016, 66(12): 5155-5160.
26.Shi X.-L., Wu Y.-H., Cheng H., Zhang X.-Q., Wang C.-S. & Xu X.-W. Complete genome sequence of astaxanthin producing bacterium Altererythrobacter ishigakiensis NBRC 107699. Mar Genom. 2016, 30: 77-79.
27.Wu Y.-H., Li G.-Y., Jian S.-L., Cheng H., Huo Y.-Y., Wang C.-S., Shao Z.-Z. & Xu X.-W. Croceicoccus pelagius sp. nov. and Croceicoccus mobilis sp. nov., isolated from marine environments. Int J Syst Evol Microbiol. 2016, 66(12): 4506-4511.
28.Yan J., Wu Y.-H., Meng F.-X., Wang C.-S., Xiong S.-L., Zhang X.-Y., Zhang Y.-Z., Xu X.-W. & Zhang D.-M. Pseudoalteromonas gelatinilytica sp. nov., isolated from surface seawater. Int J Syst Evol Microbiol. 2016, 66(9): 3538-3545.
29.Wu Y.-H., Maripatay, Meng F.-X., Zhang X.-Q., Wang C.-S., Tohty D. & Xu X.-W. Marinirhabdus gelatinilytica gen. nov., sp. nov., isolated from seawater. Int J Syst Evol Microbiol. 2016, 66(9): 3095-3101.
30.Zhang X.-Q., Wu Y.-H., Zhou X., Zhang X., Xu X.-W. & Wu M. Parvularcula flava sp. nov., an alphaproteobacterium isolated from surface seawater of the South China Sea. Int J Syst Evol Microbiol. 2016, 66(9): 3498-3502.
31.Maripatay, Wu Y.-H., Jian S.-L., Zhou Y.-D., Wang C.-S., Tohty D. & Xu X.-W. Aquaticitalea lipolytica gen. nov., sp. nov., isolated from Antarctic seawater. Int J Syst Evol Microbiol. 2016, 66(7): 2657-2663.
32.Huang J., Huo Y.-Y., Ji R., Kuang S., Ji C., Xu X.-W. & Li J. Structural insights of a hormone sensitive lipase homologue Est22. Sci Rep. 2016, 6, 28550: 1-12. (doi: 10.1038/srep28550)
33.Wu Y.-H., Jian S.-L., Meng F.-X., Maripatay, Tohty D., Wang C.-S. & Xu X.-W. Kordiimonas lipolytica sp. nov., isolated from seawater. Int J Syst Evol Microbiol. 2016, 66(6):2198-2204.
34.Wu Y.-H., Zhou P., Jian S.-L., Liu Z.-S., Wang C.-S., Oren A. & Xu X.-W. Pontibacter amylolyticus sp. nov., isolated from a deep-sea sediment hydrothermal vent field. Int J Syst Evol Microbiol. 2016, 66(4):1760-1767.
35.Sun C., Fu G.-Y., Zhang C.-Y., Hu J., Xu L., Wang R.-J., Su Y., Han S.-B., Yu X.-Y., Cheng H., Zhang X.-Q., Huo Y.-Y., Xu X.-W. & Wu M. Isolation and complete genome sequence of Algibacter alginolytica sp. nov., a novel seaweed-degrading Bacteroidetes bacterium with diversity of putative polysaccharide utilization loci. Appl Environ Microbiol. 2016, 82(10): 2975-2987.
36.Li Z.-Y., Wu Y.-H., Huo Y.-Y., Cheng H., Wang C.-S. & Xu X.-W. Complete genome sequence of a benzo[a]pyrene-degrading bacterium Altererythrobacter epoxidivorans CGMCC 1.7731T. Mar Genom. 2016, 25: 39-41.

教学工作 浙江大学工作期间（2005-2008），曾开设本科生必修课 3 门、研究生选修课 2 门、担任本科生班主任
本科生必修课：基因工程、遗传与分子生物学、生命科学导论实验
研究生选修课：分子生物学、微生物基因与克隆
班主任：浙江大学生命科学学院生科0603班。

软件版权登记及专利 1. 许学伟, 吴敏. 含有嗜盐菌素的钠线嗜盐古菌及其富集培养方法和用途. ZL8.8.
2. 吴敏, 许学伟, 孟凡旭, 张勇. 一种利用复合菌群处理榨菜废水的方法. ZL8.7.
3. 许学伟, 王春生, 杨俊毅, 吴敏. 一种需钠弧菌及采用该菌生产琼胶酶的方法. ZL7.0.
4. 许学伟, 王春生, 吴敏, 廖丽. 一种β-琼胶酶编码基因及基因获取方法. ZL0.7.
5. 许学伟, 吴敏, 江夏薇, 王春生,杨俊毅, 刘镇盛. 一种低温酯酶及其编码基因与应用. ZL1.0.
6. 吴月红, 许学伟, 王春生, 吴敏, 张心齐, 潘杰. 一种海洋过氧化氢酶产酶菌及其定向筛选方法.
ZL7.9.
7. 霍颖异, 许学伟, 王春生, 吴敏, 张心齐, 潘杰. 一种海洋芽孢杆菌及利用该菌生产过氧化氢酶的方法.
ZL7.8.
8. 吴月红, 江夏薇, 许学伟, 魏笑莲, 王春生, 吴敏. 一种海洋细菌新型酯酶及其制备方法与应用.
ZL4.0.
9. 霍颖异, 许学伟, 尹帅. 一种深海沉积物来源酯酶 EST2 及其编码基因与应用. CN5.8.
10. 霍颖异, 许学伟, 孟凡旭, 王春生, 尹帅, 崔恒林. 一种深海来源羧酸酯酶及其编码基因与应
用. CN4.5.
11. 许学伟, 霍颖异, 王春生, 孟凡旭, 王昭, 崔恒林. 一种深海新型低温耐盐酯酶及应用. CN0.9.
12. 孟凡旭, 许学伟, 霍颖异, 王春生, 简书令. 一种深海沉积物来源酯酶 EST4 及其编码基因与应用.

学术兼职 SCI期刊International Journal of Systematics of Evolutionary Microbiology编委/副编辑（2013.10－至今），国际学术期刊Frontiers in Marine Science编委/副编辑（2014.02－至今），《生物资源》编委（2016.07－2020.07），《微生物学通报》编委（2016.10－至今）
International Committee on Systematics of Prokaryotes Subcommittee on the taxonomy of Halomonadaceae委员（国际原核生物系统学委员会：盐单胞菌分类分委会，2016.05－至今）
中国海洋学会理事（第八届），中国海洋湖沼学会微生物海洋学分会理事（第一届），中国微生物学会微生物资源专业委员会理事（第三届），中国微生物学会环境微生物学专业委员会理事（2016.10－2021.10）

荣誉奖励 浙江省自然科学基金****项目获得者（2017年）
中组部第二批“****”青年拔尖人才（2015年）
中国大洋科学考察先进工作者（2014年）
海洋系统优秀科技青年（2013年）
浙江省“151 人才工程”（第三层次）（2013年）
“十一五”浙江省自然科学基金优秀成果奖（2011年）