霍小红


1. 基本信息
姓名：霍小红
职称：特别研究员、博士生导师
邮箱：huoxiaohong@sjtu.edu.cn
电话：**
主页：http://wanbin.sjtu.edu.cn/
通讯地址：上海市东川路800号上海交通大学化学化工学院B楼529室
2. 教育经历
2006-2010 河南大学，应用化学，学士
2010-2012 上海交通大学，有机化学，硕士（导师：张万斌教授）
2013-2013 Tohoku University，有机化学，Campus Asia Program（联合导师：Prof. Ilya D. GridnevandProf. Masahiro Terada）
2012-2017 上海交通大学，药学，博士（导师：张万斌教授 刘燕刚教授）
3. 工作经历
2017-2019 上海交通大学，博士后（合作导师：张万斌教授）
2019-至今 上海交通大学化学化工学院，特别研究员
4. 研究方向
1）高效不对称催化
2）重要手性药物开发和工业化研究
3) 机理研究包括实验与理论研究
5. 科研项目
主持国家自然科学基金青年项目、上海市“科技创新行动计划”青年科技英才扬帆计划、2018年中国博士后科学基金面上项目一等资助，并参与国家自然科学基金重点、重点国际合作和面上项目、上海市科委和教委重大和重点科技攻关项目等多项课题研究。
6. 荣誉奖励
1）2019年上海市“科技创新行动计划”青年科技英才扬帆计划
2）2018年上海交通大学优秀博士学位论文奖（共13名，作为毕业生代表发言）
3）2018年上海交通大学博士后考核优秀
4）2016年上海交通大学第一届学术之星（共10名）
5）2016年美国化学会上海分会研究生学术成就奖二等奖
6）2016年上海交通大学药学院“科技创新先进个人”
7）2014年博士生国家奖学金
8）2014年上海交通大学三好学生
7. 代表性论文及专著

2020
(1) VeryImportantPaper (VIP):Mo Wang,§ Lu Zhang,§Xiaohong Huo,§ Zhenfeng Zhang,§ Qianjia Yuan, Panpan Li, Jianzhong Chen, Yashi Zou, Zhengxing Wu, and Wanbin Zhang*, "Catalytic Asymmetric Synthesis of the Anti-COVID-19 Drug Remdesivir",Angew. Chem. Int. Ed.,2020, accepted.(§co-first author)

(2) Rui He,§Xiaohong Huo,§ Ling Zhao, Feijun Wang, Liyin Jiang, Jian Liao,* and Wanbin Zhang*, "Stereodivergent Pd/Cu Catalysis for the Dynamic Kinetic Asymmetric Transformation of Racemic Unsymmetrical 1,3-Disubstituted Allyl Acetates",J. Am. Chem. Soc.,2020,142, 8097-8103. (§co-first author)



(3) Guanlin Li,§ Xiaohong Huo,§ XieyangJiang, and Wanbin Zhang*, "Asymmetric Synthesis of Allylic Compoundsvia Hydrofunctionalisation and Difunctionalisation of Dienes, Allenes, and Alkynes", Chem. Soc. Rev., 2020, 49, 2060-2118. Inside front cover (§co-firstauthor)

(4) Yue Wu, Xiaohong Huo*, and Wanbin Zhang*,"Synergistic Pd/Cu Catalysis in Organic Synthesis", Chem. Eur. J., 2020, 26, 4895-4916. Invited Review

2019
(1) JiachengZhang,§ XiaohongHuo,§ Bowen Li, ZhouliChen, Yashi Zou, Zhenliang Sun*, and WanbinZhang*, "Enantioselectiveand Diastereodivergent Access to α-Substituted α-Amino Acids via Dual Iridium andCopper Catalysis", Adv. Synth. Catal., 2019, 361, 1130-1139. (§co-first author)

(2) Xiaohong Huo, Rui He, and WanbinZhang*, "Iridium/Zinc and Iridium/Copper Dual Catalysis"in SOS Reference Library: Dual Catalysis in Organic Synthesis; Gary A. MolanderEd.; 2019, accepted. Georg Thieme Verlag KG, A Thieme Group company,RuedigerstraBe 14, 70469 Stuttgart, Germany.

2019年之前
Xiaohong Huo, Jiacheng Zhang, Jingke Fu, Rui He, and Wanbin Zhang*, Ir/Cu Dual Catalysis: "Enantio-and Diastereodivergent Access to α,α-Disubstituted α-Amino Acids Bearing VicinalStereocenters", J. Am. Chem. Soc., 2018, 140, 2080-2084. (ESIHighly Cited Paper)

Penglin Liu,§ Xiaohong Huo,§ Bowen Li, Rui He,Jiacheng Zhang, Tianhong Wang, Fang Xie*, and Wanbin Zhang*, "Stereoselective Allylic Alkylation of 1-Pyrroline-5-carboxylic Esters via aPd/Cu Dual Catalysis", Org. Lett., 2018, 20, 6564-6568. (§co-first author)
Xiaohong Huo,§ Jingke Fu,§ Xiaobo He, Jianzhong Chen, Fang Xie, and WanbinZhang*, "Pd/CuDual Catalysis: Highly Enantioselective Access to α-Substituted α-Amino Acids andα-Amino Amides", Chem. Commun., 2018, 54, 599-602. (§co-first author)

Xiaohong Huo, Rui He, Jingke Fu, Jiacheng Zhang, Guoqiang Yang, and Wanbin Zhang*, "Stereoselective and Site-Specific AllylicAlkylation of Amino Acids and Small Peptides via a Pd/Cu Dual Catalysis", J. Am. Chem. Soc., 2017, 139, 9819-9822. (ESIHighly Cited Paper)

Jingke Fu, XiaohongHuo, Bowen Li, and WanbinZhang*, "Cooperativebimetallic catalysis in asymmetric allylic substitution", Org. Biomol. Chem., 2017, 15, 9747-9759. Invited Review

Jiangyan Jing, XiaohongHuo, Jiefeng Shen*, Jingke Fu, Qinghua Meng*, and Wanbin Zhang*, "DirectUse of Allylic Alcohols and Allylic Amines in Palladium-Catalyzed AllylicAmination", Chem. Commun., 2017, 53,5151-5154.
Xiaohong Huo,§ Rui He,§ Xiao Zhang, and Wanbin Zhang*, "An Ir/Zn Dual Catalysis for Enantio- andDiastereodivergent α-Allylation of α-Hydroxyketones", J.Am. Chem. Soc., 2016, 138, 11093-11096. (ESI Highly Cited Paper)(§co-first author)

Haoming Tang, XiaohongHuo, Qinghua Meng*, and WanbinZhang*, "ThePalladium-Catalyzed Allylic C-H Functionalization: The Development of NewCatalytic Systems", Acta Chimica Sinica, 2016, 74,219-233.
Xiaohong Huo, Guoqiang Yang, Delong Liu, Yangang Liu, Ilya D. Gridnev*,and Wanbin Zhang*, "Palladium-Catalyzed Allylic Alkylation ofSimple Ketones with Allylic Alcohols and Its Mechanistic Study", Angew. Chem. Int. Ed., 2014, 53, 6776-6780.
Xiaohong Huo, Mao Quan, Guoqiang Yang, Xiaohu Zhao, Delong Liu*, YangangLiu, and Wanbin Zhang*, "Hydrogen-Bond-Activated Palladium-CatalyzedAllylic Alkylation via Allylic Alkyl Ethers: Challenging Leaving Groups", Org. Lett. 2014, 16, 1570-1573.
热烈欢迎具有化学、药学背景，对科研感兴趣的硕士生、博士生和博士后加入本课题组，同时本课题组长期对本科生及国内外访问学生开放，并协助申请科研项目。