夏伟梁
博士，上海交通大学生物医学工程学院教授、博士生导师，致远学院副院长。曾于清华大学、香港大学、美国洛克菲勒大学及加州大学旧金山分校学习和深造。2008年底全职加入交大Med-X研究院从事生物医学研究和教学。获上海市科委“启明星”、上海交大晨星****、唐立新****等荣誉。中国细胞生物学学会青年工作委员会委员、美国癌症研究协会、国际大脑血流与代谢协会、中国细胞生物学学会、中国神经科学学会会员。主要研究方向: 肿瘤进展、治疗抵抗的机制及新靶点发现; 外泌体生物学及其应用; FGF/FGFR和Sirtuin在肿瘤和组织修复的作用。主持科技部973课题、国家自然科学基金委面上、医工交叉重点等项目。发表SCI收录学术论文约100篇，其中通讯或第一作者论文约70篇，H-因子37。

研究方向
肿瘤进展、治疗抵抗的机制及新靶点发现（Mechanisms of lung/prostate cancer progression and treatment resistance, and discovery of novel targets）; 外泌体生物学及其应用（biology of exosome and applications）; FGF/FGFR和Sirtuin在肿瘤和组织修复的作用（role of FGF/FGFR and sirtuin in cancer and tissue repair）。
科研项目
科技部973项目课题，国家自然科学基金委面上项目，上海交通大学医工交叉重点项目
代表性论文专著
1. Li F, Li Z, Han Q, Chen Y, Ji W, Yang Y, LuS, Xia W*. Enhanced autocrine FGF19/FGFR4signaling drives the progression of lung squamous cell carcinoma, whichresponds to mTOR inhibitor AZD2104. Oncogene. 2020;37:3507–3521.
2. Li F, Li X, Li Z, Ji W, Lu S, Xia W*. βKlotho is identified as a target for theranostics in non-smallcell lung cancer. Theranostics. 2019; 9:7474-7489.
3. Yan L, Li H*, Xia W*. Bioglasscould increase cell membrane fluidity with ion products to develop itsbioactivity. Cell Prolif. 2020;53: e12906.
4. ChengY, Zeng Q, Han Q, Xia W*. Effect of pH, temperature and freezing-thawing on quantitychanges and cellular uptake of exosomes. Protein Cell. 2019; 10:295-299.
5. Liu J, LiuY, Shao J, Li Y, Qin L, Shen H, Xie Y, XiaW*, Gao WQ*. Zeb1 is important for proper cleavage plane orientation of dividingprogenitors and neuronal migration in the mouse neocortex. Cell Death Differ.2019; 26:2479-2492.
6. Wang K, Ji W, Yu Y, Li Z, Niu X, Xia W*, Lu S*.FGFR1-ERK1/2-SOX2axis promotes cell proliferation, epithelial-mesenchymal transition, andmetastasis in FGFR1-amplified lung cancer. Oncogene. 2018;37:5340-5354.
7. Lu T, Li Z, Yang Y, Ji W, Yu Y, Niu X, Zeng Q, Xia W*, Lu S*.The Hippo/YAP1 pathway interacts with FGFR1 signaling to maintain stemness inlung cancer. Cancer Lett. 2018; 423:36-46.
8. Yang X, Geng K, Zhang Y, Zhang J, Shao J, Xia W*. Sirt3 deficiency impairsneurovascular recovery in ischemic stroke. CNS Neurosci Ther.2018;24:775-783.
9. Zhang T, Yang X, Liu T, Shao J, Fu N, Yan A, Geng K, Xia W*.Adjudin-preconditioned neuralstem cells enhance neuroprotection after ischemia reperfusion in mice. StemCell Res Ther. 2017, 8:248.
10. Yang X, Geng K, Zhang J, Zhang Y, Shao J, Xia W*. Sirt3 Mediates the InhibitoryEffect of Adjudin on Astrocyte Activation and Glial Scar Formation followingIschemic Stroke. Front Pharmacol. 2017 Dec 22;8:943.
11. Xia W*, Geng K. A sirtuinactivator and an anti-inflammatory molecule—multifaceted roles of adjudin andits potential applications for aging-related diseases. SeminCell Dev Biol.2016;59:71-78.
12. Shao J, Yang X, Liu T,Zhang T,Xie QR, Xia W*. Autophagy induction by SIRT6 isinvolved in oxidative stress-induced neuronal cell death. Protein Cell. 2016,7:281-290.
13. Chen Y, Gu H*, Zhang DS, Li F, Liu T, Xia W*.Highly effective inhibition of lungcancer growth and metastasis by systemic delivery of siRNA via multimodalmesoporous silica-based nanocarrier.Biomaterials.2014;35:10058-10069.
联系方式
邮箱地址：wlxia@sjtu.edu.cn
联系电话：86-
办公地址：教三楼 211室