戴家银(Dai Jiayin)****电子邮件：daijy65@sjtu.edu.cn

研究方向1. 新型污染物的高通量检测与识别
2. 新型污染物的人体暴露特征与健康效应
3. 新型污染物的毒性效应及分子机制
4. 基于毒性规律指导化学品绿色替代与合成
研究领域包括环境分析、环境健康与毒理学，鼓励多学科交叉研究，欢迎具有环境科学、分子生物学、组学与生物信息学、分析化学等专业背景的同学参加本科生科研，攻读硕士、博士学位。
个人简历1996年－1999年 南京大学环境学院，获博士学位
1999年－2000年 同济大学环境科学与工程学院，博士后
2000年－2001年，美国德克萨斯州立大学加尔韦斯顿医学分校，博士后
2001年－2005年，美国康奈尔大学医学院，生物化学系，博士后
2005年－2020年，中国科学院动物研究所，中国科学院动物生态与保护生物学重点实验室，主任，研究员
2020年－至今，上海交通大学环境科学与工程学院，****

国家****基金获得者（2010年），中科院"Bairen计划"入选者（2005年，终期评估优秀），美国化学会（ACS）Chemical Research in Toxicology杂志副主编（2018年1月-至今）。中国毒理学会环境与生态毒理学专业委员会 常务委员（第一~三届）；中国环境学会环境风险专业委员会 委员（2012年1月-至今）；中国环境科学学会持久性有机污染物专业委员会 委员（2012年1月-至今）；中国毒理学会计算毒理专业委员会委员（第一届-至今）；中华预防医学会环境卫生分会常务委员（第八届）。中国科学院城市环境研究所城市环境健康重点实验室 学术委员会委员（2013年1月-至今）；安徽省湿地生态保护与修复重点实验室 学术委员会委员（2018年-至今）。
先后主持或参加国家自然科学****基金项目、重点项目、重大国际合作项目、面上项目、973项目和重点研发计划的课题、中科院知识创新工程重要方向性项目、中科院战略先导B项目的课题等19项。2004年以来在Cell, Environmental Health Perspectives, Molecular Cellular Proteomics,Environmental Sciences & Technology等重要SCI刊物发表论文127篇（其中第一作者或通讯作者99篇），他引3471次，H因子35。培养的研究生多人次先后获中国科学院优秀博士论文、中国科学院院长优秀奖、朱李月华奖学金、地奥奖学金（一等和二等）、5人次获国家奖学金（博士研究生4人和硕士研究生1人）。
科研成果 代表性科研项目（10项）
1. 国家自然科学基金委重点项目（**），基于系统性毒性研究指导全氟烷基化合物替代品设计与绿色合成，2018/01-2022/12，300万，主持
2. 国家重点研发计划生殖专项，课题二（2018YFC**），男性不育的环境-基因交互作用研究，2018/12-2021/12，188万（987万），参加
3 国家自然科学基金委面上项目（**），全氟烷基化合物替代品影响斑马鱼鱼鳔发育的分子机制研究，2019/01-2022/12，66万，主持
4. 国家重点研发计划食品专项，课题五（2017YFC**），食品中典型持久性有机污染物健康危害与毒性机制，2017/01-2021/12，300万，课题负责人
5. 国家自然科学基金委面上项目（**），全氟类化合物与人类肝脏型脂肪酸结合蛋白的相互作用及毒性机制研究，2014/01-2017/12，88万，主持
6. 国家自然科学基金国际(地区)合作与交流项目（），野生动物体内全氟烷基化合物的来源、存在状态及毒性机制研究，2014/1-2018/12，274万，主持
7. 中科院先导B专项，项目四课题二子课题二（XDB**），典型污染物引发机体糖和脂肪代谢紊乱的机制，2014/07-2019/06，421万，子课题负责人
8. 国家重点基础研究发展计划（973计划），课题四（2013CB945204），血脂紊乱影响精子发生的生物标记物的鉴定和临床干预，2013/01-2017/08，556万，课题负责人
9. 国家自然科学基金委****基金项目（**），持久性有机污染物的生态毒理机制，2011/01-2014/12，200万元，主持
10. 国家自然科学基金委重点项目（**），典型全氟有机污染物的水环境过程及生态毒理机制研究，2009/01-2012/12，200万元，主持
近五年代表性论文（30篇）
(1) Yao Jingzhi, Pan Yitao, Sheng Nan, Su Zhaoben, Guo Yong, WangJianshe, Dai, Jiayin^(*), Novel perfluoroalkylether carboxylic acids (PFECAs) and sulfonic acids (PFESAs): Occurrence and associationwith serum biochemical parameters in residents living near a fluorochemical plantin China, Environmental Science & Technology, 2020, 54 (21): 13389-13398
(2) Wang Jinghua,Pan Yitao, Wei Xiaofei, Dai, Jiayin^(*), TemporalTrends in Prenatal Exposure (1998-2018) to Emerging and Legacy Per- andPolyfluoroalkyl Substances (PFASs) in Cord Plasma from the Beijing Cord BloodBank, China, Environmental Science & Technology, 2020, 54 (20): 12850-12859
(3) Cui Qianqian, Pan Yitao, Wang Jinghua, Liu Hongxiu, YaoBing, Dai, Jiayin^(*), Exposure to per- and polyfluoroalkyl substances (PFASs) inserum versus semen and their association with male reproductive hormones, EnvironmentalPollution, 2020, 266 (2): 115330
(4) Liu Hongxiu^(#), Pan Yitao^(#), Jin Shuna; Sun Xiaojie, Jiang Yangqian, Wang Yuyan,Ghassabian Akhgar, Li Yuanyuan, Xia Wei, Cui Qianqian, Zhang Bin, Zhou Aifen, DaiJiyin^(*), Xu Shunqing^(*). Associations between six common per- and polyfluoroalkylsubstances and estrogens in neonates of China. Journal of hazardousmaterials, 2020, 124378
(5) Liu Hongxiu^(#), Pan Yitao^(#), Jin Shuna, Li Yuanyuan, Zhao Liuqing, Sun Xiaojie, Cui Qianqian, Zhang bin, Zheng Tongzhang, Xia Wei, ZhouAifen, Campana Anna Maria, Dai Jiyin^(*), Xu Shunqing^(*). Associations of per-/polyfluoroalkyl substances withglucocorticoids and progestogens in newborns, Environment International, 2020, 140: 105636
(6) Pan, Yitao, Wang, Jinghua,Yeung, L. W. Y., Wei, Si, Dai, Jiayin^(*), Analysis of emerging per- andpolyfluoroalkyl substances: Progress and current issues, Trends inAnalytical Chemistry, 2020, 124: 115481
(7) Wang, Jinxing^(#), Shi Guohui^(#), YaoJingzhi, Sheng Nan, Cui, Ruina, Su Zhaoben, Guo, Yong, Dai, Jiayin^(*), Perfluoropolyether carboxylic acids (novel alternativesto PFOA) impair zebrafish posterior swim bladder development via thyroidhormone disruption, Environment International, 2020, 134: 105317
(8) Pan, Yitao, Cui, Qianqian,Wang, Jinghua, Sheng Nan, Jing, Jun, Yao, Bing^(*), Dai, Jiayin^(*), Profiles of Emerging and Legacy Per-/PolyfluoroalkylSubstances in Matched Serum and Semen Samples: New Implications for Human SemenQuality, Environmental Health Perspectives, 2019, 127 (12): 127005
(9) Cui, Qianqian^(#), Shi, Fanglei^(#), Pan, Yitao, Zhang, Hongxia, Dai, Jiayin^(*), Per- and polyfluoroalkyl substances (PFASs) in the blood oftwo colobine monkey species from China: Occurrence and exposure pathways, Scienceof the Total Environment, 2019, 674: 524-531
(10) Guo, Hua, Wang, Jinghua, Yao,Jingzhi, Sun, Sujie, Sheng, Nan, Zhang, Xiaowen, Guo, Xuejiang, Guo, Yong, Sun,Yan, Dai, Jiayin^(*), Comparative hepatotoxicity of novel PFOA alternatives(perfluoropolyether carboxylic acids) on Male Mice, Environmental Science& Technology, 2019, 53 (7): 3929-3937
(11) Shi, Guohui, Cui, Qianqian,Wang, Jinxing, Guo, Hua, Pan, Yitao, Sheng, Nan, Guo, Yong, Dai, Jiayin^(*), Chronic exposure to 6:2 chlorinated polyfluorinated ethersulfonate acid (F-53B) induced hepatotoxic effects in adult zebrafish anddisrupted the PPAR signaling pathway in their offspring, EnvironmentalPollution, 2019, 249: 550-559
(12) Shi, Guohui, Wang, Jinxing,Guo, Hua, Sheng, Nan, Cui, Qianqian, Pan, Yitao, Guo, Yong, Sun, Yan, Dai, Jiayin^(*), Parental exposure to 6:2 chlorinated polyfluorinated ethersulfonate (F-53B) induced transgenerational thyroid hormone disruption inzebrafish, Science of the Total Environment, 2019, 665: 855-863
(13) Sun, Sujie, Guo, Hua, Wang,Jianshe^(*), Dai, Jiayin, Hepatotoxicity of perfluorooctanoic acid and twoemerging alternatives based on a 3D spheroid model, Environmental Pollution,2019, 246: 955-962
(14) Cui, Ruina, Li, Chenyang,Wang, Jianshe^(*), Dai, Jiayin, Induction of hepatic miR-34a by perfluorooctanoic acidregulates metabolism-related genes in mice, Environmental Pollution,2019, 244: 270-278
(15) Wang, Jinghua^(#), Pan, Yitao^(#), Cui, Qianqian, Yao, Bing,Wang, Jianshe^(*), Dai, Jiayin, Penetration of PFASs across the BloodCerebrospinal Fluid Barrier and Its Determinants in Humans, EnvironmentalScience & Technology,2018, 52 (22): 13553-13561
(16) Sun, Sujie, Wang, Jianshe^(*), Lu,Yin, Dai, Jiayin,Corticosteroid-Binding Globulin, Induced in Testicular Leydig Cells byPerfluorooctanoic Acid, Promotes Steroid Hormone Synthesis, Archives ofToxicology, 2018, 92 (6): 2013-2025
(17) Zhou,Xiujuan, Wang, Jianshe^(*),Sheng, Nan, Cui, Ruina, Deng, Yiqun, Dai,Jiayin, Subchronic Reproductive Effects of 6:2 Chlorinated PolyfluorinatedEther Sulfonate (6:2 Cl-Pfaes), an Alternative to PFOS, on Adult Male Mice, Journalof Hazardous Materials, 2018,358: 256-264
(18) Zhang, Hongxia, Zhou, Xiujuan, Sheng, Nan,Cui, Ruina, Cui, Qianqian, Guo, Hua, Guo, Yong, Sun, Yan, Dai, Jiayin*, Subchronic hepatotoxicity effects of 6:2 chlorinatedpolyfluorinated ether sulfonate (6:2 Cl-PFESA), a novelperfluorooctanesulfonate (PFOS) alternative, on adult male mice, EnvironmentalScience & Technology,2018, 52 (21): 12809-12818
(19) Shi, Guohui, Guo, Hua, Sheng, Nan, Cui,Qianqian, Pan, Yitao, Wang, Jinxing, Guo, Yong, Dai, Jiayin*, Two-generational reproductive toxicity assessment of 6:2chlorinated polyfluorinated ether sulfonate (F-53B, a novel alternative to perfluorooctanesulfonate) in Zebrafish, Environmental Pollution, 2018, 243:1517-1527
(20) Cui,Qianqian, Pan, Yitao, Zhang, Hongxia, Sheng, Nan, Dai, Jiayin^(*),Elevated concentrations of perfluorohexanesulfonate and other per andpolyfluoroalkyl substances in Baiyangdian Lake (China): source characterizationand exposure assessment, Environmental Pollution, 2018, 241: 684-691
(21) Cui,Qianqian^(#),Pan, Yitao^(#),Zhang, Hongxia, Sheng, Nan, Wang, Jianshe, Guo, Yong, Dai, Jiayin^(*),Occurrence and tissue distribution of novel ferfluoroether carboxylic andsulfonic acids and legacy per/polyfluoroalkyl substances in Black-Spotted Frog(Pelophylax Nigromaculatus), Environmental Science & Technology,2018, 52 (3): 982-990 （ESI数据库（highlycited papers）收录）
(22) Pan, Yitao^(#), Zhang, Hongxia^(#), Cui, Qianqian, Sheng, Nan, Yeung, Leo W. Y., Sun, Yan, Guo,Yong, Dai, Jiayin^(*), Worldwide distribution of novel perfluoroether carboxylicand sulfonic acids in surface water, Environmental Science & Technology,2018, 52 (14): 7621-7629 （ESI数据库（highlycited papers）收录）
(23) Sheng, Nan, Cui, Ruina, Wang,Jinghua, Guo, Yong, Wang, Jianshe, Dai,Jiayin^(*), Cytotoxicity of novelfluorinated alternatives to long-chain perfluoroalkyl substances to human livercell Line and their binding capacity to human liver fatty acid binding protein, Archives of Toxicology, 2018, 92 (1): 359-369 （ESI数据库（highlycited papers）收录）
(24) Sheng,Nan, Pan, Yitao, Guo, Yong, Sun, Yan, Dai,Jiayin^(*),Hepatotoxic effects of hexafluoropropylene oxide trimer acid (HFPO-TA), a novelperfluorooctanoic acid (PFOA) alternative, on mice, Environmental Science& Technology, 2018, 52 (14): 8005-8015
(25) Shi,Guohui, Xie, Yu, Guo, Yong, Dai, Jiayin^(*), 6:2Fluorotelomer sulfonamide alkylbetaine (6:2 ftab), a novel perfluorooctanesulfonate alternative, induced developmental toxicity in Zebrafish embryos, AquaticToxicology, 2018, 195: 24-32
(26) Pan Yitao, Zhang Hongxia, Cui Qianqian,Sheng Nan, Yeung Leo W. Y., Guo Yong, Sun Yan, Dai, Jiayin^(*).Firstreport on the occurrence and bioaccumulation of hexafluoropropylene oxidetrimer acid: an emerging concern, Environmental Science &Technology, 2017,51(17): 9553-9560
(27) Shi Guohui, Cui Qianqian, Pan Yitao, ShengNan, Guo Yong, Dai, Jiayin^(*).6:2 fluorotelomer carboxylicacid (6:2 FTCA) exposure induces developmental toxicity and inhibits theformation of erythrocytes during zebrafish embryogenesis, Aquatic Toxicology,2017, 190: 53-61
(28) Shi, Guohui, Cui, Qianqian, Pan, Yitao,Sheng, Nan, Sun, Sujie, Guo, Yong, Dai, Jiayin^(*), 6:2Chlorinated polyfluorinated ether sulfonate, a PFOS alternative, inducesembryotoxicity and disrupts cardiac development in zebrafish embryos, AquaticToxicology, 2017, 185: 67-75 （ESI数据库（highlycited papers）收录）
(29) Yan, Shengmin, Zhang, Hongxia, Guo,Xuejiang, Wang, Jianshe, Dai, Jiayin^(*), Highperfluorooctanoic acid exposure induces autophagy blockage and disturbsintracellular vesicle fusion in the liver, Archives of Toxicology, 2017,91 (1): 247-258
(30) Pan, Yitao^(#), Zhu, Yingshuang^(#),Zheng, Tongzhang, Cui, Qianqian, Buka, Stephen L, Zhang, Bin, Guo, Yong, Xia,Wei, Yeung, Leo W Y, Li, Yuanyuan, Zhou, Aifen, Qiu, Lin, Liu, Hongxiu, Jiang,Minmin, Wu, Chuansha, Xu, Shunqing^(*), Dai, Jiayin^(*),Novel chlorinated polyfluorinated ether sulfonates and legacyper-/polyfluoroalkyl substances: placental transfer and relationship with serumalbumin and glomerular filtration rate, EnvironmentalScience & Technology,2017, 51 (1): 634-644 （ESI数据库（highlycited papers）收录）
荣获奖励中国科学院优秀导师奖（2019年度）；
中国科学院朱李月华优秀教师奖（2012年度）；

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