导师介绍

导师姓名
刘德龙
导师性别男
职务职称副研究员.
所在院系药学院
所属学科药学
研究方向有机药物合成不对称催化
联系电话34207176
电子邮箱dlliu@sjtu.edu.cn

个人简介

于2007年在上海交通大学获得应用化学专业工学博士，随后在化学流动站进行博士后研究，出站后留药学院。目前主要从事手性配体的设计合成及其在药物&关键中间体的不对称合成中的应用研究。与人合作已在J.Am.Chem.Soc.,J.Org.Chem.,Org.Biomol.Chem.,等刊物上发表了十余篇SCI论文并申请了十多项国际及国内专利，参与编写了国际著名出版社Wiley-VCH邀编的有关手性配体及药物合成方面的两本书中的部分章节。作为项目负责人承担多项国家自然科学基金及上海市等科研项目。
代表性论著

参与撰写的专著二本：1.DelongLiu,WanbinZhang.《PharmaceuticalProcessChemistry》,Chapter14,2010,273~302,Wiley-VCH:Weinheim,Germany.2.WanbinZhang,DelongLiu.《ChiralFerrocenesinAsymmetricCatalysis》,Chapter7,2009,175-214,Wiley-VCH:Weinheim,Germany.近年来发表的与课题相关论文：1.HuiGuo,DelongLiu,Nicholas.Butt,YangangLiu,WanbinZhang,"EfficientRu(II)-CatalyzedAsymmetricHydrogenationofSimpleKetoneswithC2-SymmetricPlanarChiralMetallocenylPhosphinooxazolineLigands”,Tetrahedron,2012,68,3295-3299.2.LinaZhao,JiefengShen,DelongLiu,YangangLiu,WanbinZhang,"HighlyEfficientAsymmetricMichaelAdditionofAldehydetoNitroolefinusingPerhydroindolicAcidasaChiralOrganocatalyst",Org.Biomol.Chem.,2012,10,2840-2846.3.XiaohuZhao,DelongLiu(并列第一作者),HuiGuo,YangangLiu,WanbinZhang,“C-NBondCleavageofAllylicAminesviaHydrogenBondActivationwithAlcoholSolventsinPd-CatalyzedAllylicAlkylationofCarbonylCompounds”,J.Am.Chem.Soc,2011,133，19354-19357.ThispaperwasoneofthemostreadmanuscriptsinNov.2011.FeaturedinSYNFACTS2012,8,0182.4.XiaohuZhao,DelongLiu,FangXie,YangangLiu,WanbinZhang,“Efficientpalladium-catalyzedasymmetricallylicalkylationofketonesandaldehydes”,OrganicBiomoleculeChemistry,2011,9,1871-1875.5.YanlanWang,DelongLiu,andWanbinZhang,“AsymmetricRu(II)-CatalyzedHydrogenationofKetoneswithC1-PlanarChiralRuthenocene-basedP,N-Ligands”,Tetrahedron:Asymmetry,2009,20,2510-2512.6.XiaohuZhao,DelongLiu,FangXie,andWanbinZhang,“Enamines:Efficientnucleophilesforthepalladium-catalyzedasymmetricallylicalkylation”,Tetrahedron,2009,65,512-517.7.DelongLiu,FangXie,andWanbinZhang,“EnantioselectiveTransferHydrogenationofKetoneswithPlanarChiralRuthenocene-basedPhosphinooxazolineLigands”,Tetrahedron,2008,64,3561-3566.8.FangXie,DelongLiu,andWanbinZhang,“Reversalinenantioselectivityforthepalladium-catalyzedasymmetricallylicsubstitutionwithnovelmetallocene-basedplanarchiraldiphosphineligands”,TetrahedronLetters,2008,49,1012-1015.9.DelongLiu,FangXie,andWanbinZhang,“NovelC2-SymmetricPlanarChiralDiphosphineLigandsandTheirApplicationinPd-CatalyzedAsymmetricAllylicSubstitutions”,TheJournalofOrganicChemistry,2007,72,6992-6997.10.DelongLiu,FangXie,andWanbinZhang,“Palladium-CatalyzedAsymmetricAllylicAlkylationwithanEnamineastheNucleophilicReagent”,TetrahedronLetters,2007,48,7591-7594.11.DelongLiu,FangXie,andWanbinZhang,“TheSynthesisofNovelC2-SymmetricP,N-ChelationRuthenoceneLigandsandTheirApplicationinPalladium-CatalyzedAsymmetricAllylicSubstitution”,TetrahedronLetters,2007,48,585-588.12.GenghongHua,DelongLiu,FangXie,andWanbinZhang,“TheSynthesisandApplicationofNovelC2-SymmetricChiralN,N,O,O-BisoxazolineLigandswithaFerroceneBackbone”,TetrahedronLetters,2007,48,385-388.已授权的专利：1)“(2S,4S)-1-(4-硝基苄氧羰基)-2-[(3-烯丙氧羰基)-苯基氨基甲酰基]-吡咯烷-4-基硫醇的制备方法”张万斌,刘德龙,罗丽,等.授权专利：ZL200510030662.4.2)“C2-对称手性二茂钌配体及其合成方法”张万斌,谢芳,刘德龙,等.授权专利：ZL200610027407.9.3)“C2-对称的只具有面手性的二茂钌双膦配体”张万斌,谢芳,刘德龙,等.授权专利号:ZL200610027409.8.4)“C2-对称的只具有面手性的二茂钌双膦配体的合成方法”张万斌,谢芳,刘德龙,等.授权专利号:ZL200610027408.3.5)"他培南钠盐的制备方法"张万斌,刘德龙,罗丽,谢芳,授权专利号:ZL200610027408.3.ZL200510030660.5.6)"烯胺用于钯催化不对称烯丙基烷基化反应中的方法"张万斌,谢芳,刘德龙,授权专利号:ZL200710045897.X.7)"头孢妥仑酯的制备方法"张万斌,刘德龙,授权专利号:ZL200910052147.4.