摘要/Abstract

以乙酰丙酮钌和膦胺配体作为催化剂体系，用于催化丙二酸二甲酯加氢制3-羟基丙酸甲酯.围绕催化反应性能，系统探讨了配体结构和用量、温度、时间以及溶剂等对丙二酸二甲酯转化率和3-羟基丙酸甲酯产率的影响.研究发现，乙酰丙酮钌和o-二苯基膦苯胺构成的催化剂体系在合适反应条件下可以有效催化丙二酸二甲酯选择性加氢制3-羟基丙酸甲酯.在优化的反应条件下，这一催化体系也可以催化多种不同结构酯类分子加氢制醇.
关键词: 乙酰丙酮钌, o-二苯基膦苯胺, 丙二酸二甲酯, 3-羟基丙酸甲酯
Ruthenium acetylacetonate and aminophosphine ligand were selected as the catalyst system and applied to the catalytic hydrogenation of dimethyl malonate into methyl 3-hydroxypropanoate. With the focus on the catalytic efficiency, the important factors with significant influences on the dimethyl malonate conversion and methyl 3-hydroxypropanoate selectivity were well discussed, including the structure and dosage of the ligand, temperature, reaction time, solvent, and so on. The results revealed that catalyst system of ruthenium acetylacetonate and o-(diphenylphosphino)aniline ligand could obtain significant catalytic results. Under the optimal reaction conditions, this catalyst system can also be applied to catalytic hydrogenation of some other esters with high efficiency.
Key words: ruthenium acetylacetonate, o-(diphenylphosphino)aniline, dimethyl malonate, methyl 3-hydroxypropanoate


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