姓 名:
朱正江 性 别:
男
职 称:
研究员 学 历:
博士研究生
电 话:
传 真:
电子邮件:
jiangzhu@sioc.ac.cn 个人主页:
通讯地址:
上海市浦东新区秋月路26号6号楼 200032
简历:
2002-2006,南京大学化学系, 获理学学士学位
2006-2011,美国马萨诸塞大学阿默斯特分校(UMass-Amherst),获哲学博士学位
2011-2013,美国加州斯克利普斯(Scripps)研究所,博士后
2013.9-至今 中国科学院生物与化学交叉研究中心 研究员、课题组长
研究方向:
朱正江课题组主要发展基于质谱技术的代谢组学先方法,并将代谢组学技术应用于研究与健康、疾病相关的生命医学问题。具体方向为(1)发展新型质谱方法结合生物信息学实现高通量、全定量代谢组学技术;(2)代谢组学生物信息学平台及代谢物数据库建设;(3)运用代谢组学技术研究衰老及神经退行性疾病
专家类别:
研究员
职务:
课题组长
社会任职:
获奖及荣誉:
Proctor and Gamble杰出研究奖, University of Massachusetts -Amherst (2010)
Marvin D. Rausch杰出墙报奖,University of Massachusetts -Amherst (2008)
南京大学化学优秀实验奖 (2006)
南京大学德尔奖学金 (2004)
代表论著:
1.H. Zha, Y. Cai, Y. Yin, Z. Wang, K. Li, and Z.-J. Zhu*, SWATHtoMRM: Development of High-Coverage Targeted Metabolomics Method Using SWATH Technology for Biomarker Discovery, Analytical Chemistry, 2018, In Press.
2.J. Tu, Y. Yin, M. Xu, R. Wang, and Z.-J. Zhu*, Absolute Quantitative Lipidomics Reveals Lipidome-Wide Alterations in Aging Brain, Metabolomics, 2018, 14: 5.
3.Z. Zhou, J. Tu, and Z.-J. Zhu*, Advancing the Large-Scale CCS Database for Metabolomics and Lipidomics at the Machine-Learning Era, Current Opinion in Chemical Biology, 2018, 42, 34-41.
4.Z. Zhou, J. Tu, X. Xiong, X. Shen, and Z.-J. Zhu*, LipidCCS: Prediction of Collision Cross-Section Values for Lipids with High Precision to Support Ion Mobility-Mass Spectrometry based Lipidomics, Analytical Chemistry, 2017, 89, 9559–9566.
5.Z. Zhou, X. Xiong, and Z.-J. Zhu*, MetCCS Predictor: A Web Server for Predicting Collision Cross-Section Values of Metabolites in Metabolomics, Bioinformatics, 2017, 33, 2235-2237.
6.Z. Zhou, X. Shen, J. Tu, and Z.-J. Zhu*, Large-Scale Prediction of Collision Cross-Section Values for Metabolites in Ion Mobility - Mass Spectrometry, Analytical Chemistry, 2016, 88, 11084-11091.
7.H. Li, Y. Cai, Y. Guo, F. Chen, and Z.-J. Zhu*, MetDIA: Targeted Metabolite Extraction of Multiplexed MS/MS Spectra Generated by Data-Independent Acquisition, Analytical Chemistry, 2016, 88, 8757-8764.
8.J. Wang*, T. Zhang, X. Shen, J. Liu, D. Zhao, Y. Sun, L. Wang, Y. Liu, X. Gong, Y. Liu, Z.-J. Zhu*, and F. Xue*, Serum Metabolomics for Early Diagnosis of Esophageal Squamous Cell Carcinoma by UHPLC-QTOF/MS, Metabolomics, 2016, 12: 116.
9.X. Shen, X. Gong, Y. Cai, Y. Guo, J. Tu, H. Li, T. Zhang, J. Wang, F. Xue, and Z.-J. Zhu*, Normalization and Integration of Large-Scale Metabolomics Data Using Support Vector Regression, Metabolomics, 2016, 12: 89.
10.Y. Cai, K. Weng, Y. Guo, J. Peng, and Z.-J. Zhu*, An Integrated Targeted Metabolomic Platform for High-Throughput Metabolite Profiling and Automated Data Processing, Metabolomics, 2015, 11, 1575-1586.
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