徐宏喜
徐宏喜教授，现为上海中医药大学首席教授、博士生导师、上海中医药大学中药学院院长。国家中组部“****”特聘教授，上海市首批“****’特聘专家。1994年获得日本富山医科药科大学国立和汉药研究所药学博士学位。并于新加坡国立大学化学系及加拿大Dalhousie大学微生物学系进行博士后研究工作。曾先后受聘于香港中文大学中药研究中心科学主任、香港和记黄埔(中国)有限公司副总经理兼高级医药顾问，上海和黄药业有限公司董事兼研究开发总监。2001至2010年,担任香港赛马会中药研究院副总裁兼中药研究室主任。徐教授至今已发表SCI论文270多篇，被SCI源期刊引用7100余次，H指数为47。入选2014、2015及2016年中国高被引用学者榜。获授权美国发眀专利6项，PCT专利1项，中国发明专利11项。培养博士后25人，博士研究生9人，主编专著3部。

人物介绍
徐教授的主要社会兼职包括：中华中医药学会中药实验药理学分会主任委员、世界中医药协会联合会中药分析专业委员会副会长、世中联中药鉴定专业委员会副会长、全国中医药高等教育学会中药教育研究会第三届理事会副理事长、国家药典会天然药物专业委员会委员，国际现代化中医药学术会议联席主席、上海市侨界知识分子联谊会第八届理事会常务理事、上海市药学会中药专业委员会主任委员、香港中药药理学会付会长、国际国内十余种学术刊物的编委、现代化中医药国际协会创会董事等职。先后50 余次应邀前往美国、日本、新加坡、韩国、巴西、加拿大、奥地利、印度等国家以及台湾、香港、澳门等地做特邀学术报告或学术大会报告。
徐宏喜
代表性论文
1. G. Lin, J. Y. Wang, N. Li, M. Li, H. Gao, Y. Ji, F. Zhang, H. L. Wang, Y. Zhou, Y. Ye, H. X. Xu, J. Zheng, Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum, Journal of Hepatology, 54(4), 666-673 (2011). (IF=12.486)
2. Y. Y. Li, Y. Lu, S. W. Wang, Z. J. Han, F. X. Zhu, Y. M. Ni, R. Liang, Y. Zhang, Q. B. Leng, G. Wei, G. C. Shi, R. H. Zhu, D. Li, H. K. Wang, S. G. Zheng, H. X. Xu, A.Tsun, B. Li, USP21 prevents the generation of T-helper-1-like Treg cells, Nature Communications, 7: 13559 (2016).（IF=12.124）
3. M.H.Feng, B.Q.Tang, N.Z.Wang, H. X. Xu, X.F.Jiang, Ligand Controlled Regiodivergent C1 Insertion on Arynes for Construction of Phenanthridinone and Acridone Alkaloids, Angewandte Chemie (International ed. in English), 54(49), 14960-4 (2015). (IF=11.994)
4.H. L. Zhao, Y. Sui, C. F. Qiao, K. Y. Yip, R. K. K. Leung, S. K. W. Tsui, H. M. Lee, H. K. T. Wong, X. Zhu, J. J. Siu, L. He, J. Guan, L. Z. Liu, H. X. Xu, P. C. Y. Tong, J. C. N. Chan, Sustained antidiabetic effects of a berberine-containing Chinese herbal medicine through regulation of hepatic gene expression, Diabetes, 61(4), 933-943 (2012). (IF=8.684)
5. Y. Z. Lao, G. Wan, Z. Y. Liu, X. Y. Wang, P. Ruan, W. Xu, D. Q. Xu, W. D. Xie, Y. Zhang, H. X. Xu, N. H. Xu, The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation, Autophagy, 10(5): 1-14 (2014). (IF= 8.593)
6. G. Wan, W. D. Xie, Z. Y. Liu, W. Xu, Y. Z. Lao, N. Huang, K. Cui, M. J. Liao, J. He, Y. Y. Jiang, Burton B Yang, H. X. Xu, N. H. Xu, Y. Zhang, Hypoxia-induced MIR155 is a potent autophagy inducer by targeting multiple players in the MTOR pathway, Autophagy, 10(1): 70-79 (2014). (IF= 8.593)
7. M. H. Feng, B .Q. Tang, H. X. Xu, X. F. Jiang, Collective Synthesis of Phenanthridinone through C-H Activation Involving a Pd-Catalyzed Aryne Multicomponent Reaction, Organic Letters, 18(17):4352-5(2016). (IF=6.579)
8. Y. Liao, X. Liu, J. Yang, Y.Z. Lao, X.W.Yang, X.N.Li, J.J.Zhang, Z.J.Ding, H. X. Xu and G. Xu, Hypersubones A and B, New Polycyclic Acylphloroglucinols with Intriguing Adamantane Type Cores from Hypericum subsessile, Organic Letters, 17 (5), 1172–1175(2015). (IF=6.579)
9. Q. B. Han, T. F. Tso, S. Cheung, Tai, J. Z. Song, C. F. Qiao, H. D. Sun, and H. X. Xu, Maoecrystal Z, a Cytotoxic Diterpene from Isodon eriocalyx with an Unique Skeleton, Organic Letters, 8 (21), 4727-4730 ( 2006). (IF=6.579)
10. W. L. Ting Kan, C. Yin, H. X. Xu, G. Xu, K. K. W. To, C. H. Cho, J. A. Rudd, G. Lin, Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G0/G1 cell cycle arrest and apoptosis, International Journal of Cancer, 132(3): 707-716 (2013). (IF=6.513)
11. C. Feng, L. Y. Zhou, T. Yu, G. Xu, H. L. Tian, J. J. Xu, H. X. Xu, K. Q. Luo, A new anticancer compound, Oblongifolin C, inhibits tumor growth and promotes apoptosis in HeLa cells through bax activation, International Journal of Cancer, 131(6): 1445-1454 (2012). (IF=6.513)
12. L.Zhang, J.L.Feng, S.Y.Kong, M.Wu, Z.C.Xia, B.J.Zhang, W.W.Fu, Y.Z.Lao, H.S.Tan, H. X. Xu.Nujiangexathone A, a novel compound from Garcinia nujiangensis,suppresses cervical cancer growth by targeting hnRNPK, Cancer letters, 380(2):447-456 (2016).(IF=6.375)
13. T. W. D. Chan, P. P. H. But, S. W. Cheng, I. M. Y. Kwok, F. W. Lau, H. X. Xu, Differentiation and authentication of Panax ginseng, Panax quinquefolius and ginseng products by using HPLC/MS, Analytical Chemistry, 72(6), 1281-1287 (2000). (IF=6.320)
14. X. W. Yang, X. Deng, X. Liu, C. Y. Wu, X. N. Li, B. Wu, H. R. Luo, Y. Li, H. X. Xu, Q. S. Zhao, G. Xu, Hypercohin A, a new polycyclic polyprenylated acylphloroglucinols possessing an unusual bicyclo[5.3.1]hendecane core from Hypericum cohaerens, Chemical Communications, 48: 5998-6000 (2012). (IF=6.319)
15. Z.C.Xi, M.Yao, Y.Li, C.L.Xie, J. Holst, T. Liu, S.F.Cai, Y.Z.Lao, H.S.Tan, H. X. Xu and Q.H. Dong, Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation, Cell Death & Disease, 7(6):e2252 (2016). (IF=5.965)
16. K.K. Shen, J.L.Xie, H. Wang, H.Zhang, M.Y.Yu, F.F. Lu, H.S. Tan, H. X. Xu, Cambogin induces caspase-independent apoptosis through the ROS/JNK pathway and epigenetic regulation in breast cancer cells, Molecular Cancer Therapeutics, 14(7):1738-1749. (2015). (IF=5.764)
17. K.K.Shen, F.F.Lu, J.L.Xie, M.F.Wu, B.Cai, Y.R.Liu, H.Zhang, H.S.Tan, Y.Y.Pan, H. X. Xu.Cambogin exerts anti-proliferative and pro-apoptotic effects on breast adenocarcinoma through the induction of NADPH oxidase 1 and the alteration of mitochondrial morphology and dynamics, Oncotarget, doi: 10.18632/oncotarget.10585. [Epub ahead of print] (2016). (IF=5.168)
18. K.K.Shen, Z.C.Xi, J.L.Xie, H.Wang, C.L.Xie, C.S.Lee, P. Fahey, Q.H.Dong, H. X. Xu.Guttiferone K suppresses cell motility and metastasis of hepatocellular carcinoma by restoring aberrantly reduced profilin 1, Oncotarget, in press, (2016). (IF=5.168)
19. M.J.Wang, Q. Dong, H. Wang, Y.Q. He, Y.Chen, H.Zhang, R.Wu, X.C.Chen, B.P.Zhou, J.He, H.F.Kung, C.H.Huang, Y.Q.Wei, J.D.Huang, H. X. Xu, M.L.He, Oblongifolin M, an active compound isolated from a Chinese medical herb Garcinia oblongifolia, potently inhibits enterovirus 71 reproduction through downregulation of ERp57, Oncotarget, 7(8):8797-808. (2016). (IF=5.168)
20. Z.J.Ding, Y.Z.Lao, H.Zhang, W.W.Fu, L.L.Zhu, H.S.Tan, H. X. Xu, Griffipavixanthone, a dimeric xanthone extracted from edible plants, inhibits tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer, Oncotarget, 12;7(2):1826-37 (2015) (IF=5.168)
21. 26. H.Zhang, D. Zheng，H.H. Li，H.Wang，H.S.Tan, H. X. Xu, Diagnostic filtering to screen polycyclic polyprenylated acylphloroglucinols from Garcinia oblongifolia by ultrahigh performance liquid chromatography coupled with ion mobility quadrupole time-of-flight mass spectrometry, Analytica Chimica Acta,912:85-96. (2015).（IF=4.950）
22. Y. Zhou, N. Li, F. F. K. Choi, C. F. Qiao, J. Z. Song, S. L. Li, X. Liu, Z. W. Cai, P. P. Fu, G. Lin, H. X. Xu, A new approach for simultaneous screening and quantification of toxic pyrrolizidine alkaloids in some potential pyrrolizidine alkaloid-containing plants by using ultra performance liquid chromatography-tandem quadrupole mass spectrometry, Analytica Chimica Acta, 681(1-2), 33-40 (2010). (IF=4.950)
23. Y. Zhou, Stephanie Lee, Franky F. K. Choi, G. Xu, X. Liu, J. Z. Song, S. L. Li, C. F. Qiao, H. X. Xu, Qualitative and quantitative analysis of polycyclic polyprenylated acylphloroglucinols from Garcinia species using ultra performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry, Analytica Chimica Acta, 678(1), 96-107 (2010). (IF=4.950)
24. Y. Zhou, X. Liu, J. Yang, Q. B. Han, J. Z. Song, S. L. Li, L. S. Ding, H. X. Xu, Analysis of caged xanthones from the resin of Garcinia hanburyi using ultraperformance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry, Analytica Chimica Acta, 629, 104-118 (2008). (IF=4.950)
25.H.He, L.S.Ding, H. X. Xu, X.X.Lei, H.P.Xiao, Y.Zhou,Gymnothelignans A-O: Conformation and Absolute Configuration Analyses of Lignans Bearing Tetrahydrofuran from Gymnotheca chinensis,Journal of Organic Chemistry, 77(19): 8435-8443 (2012). (IF=4.849)
26. H. Y. Qin, J. C. Y. Wu, X. D. Tong, J. J. Y. Sung, H. X. Xu, Z. X. Bian, Systematic review of  animal models of post-infectious/post-inflammatory irritable bowel syndrome. Journal of Gastroenterology, 46(2), 164-174 (2011). (IF=4.658)
27. Z. X. Bian, Z. Li, Z. X. Huang, M. Zhang, H. L. Chen, H. X. Xu, J. J. Y. Sung, Unbalanced expression of protease-activated receptors-1 and -2 in the colon of diarrhea-predominant irritable bowel syndrome patients, Journal of Gastroenterology, 44(7), 666-674 (2009). (IF=4.658)
28. Y.Lu, S.F.Cai, J.Nie, Y.Y. Li, G.C.Shi, J.M.Hao, W.W.Fu, H.S.Tan, S.L.Chen, B. Li, H. X. Xu ,The natural compound nujiangexanthone A suppresses mast cell activation and allergic asthma, Biochemical Pharmacology, 100:61-72(2015). (IF=4.581)
29. H. S. Tan, D. D. Hu, J. Z. Song, Y. Xu, S. F. Cai, Q. L. Chen, Q. W. Meng, S. L. Li, S. L. Chen, Q. Mao, H. X. Xu, Distinguishing Radix Angelica sinensis from different regions by HS-SFME/GC-MS,  Food chemistry, 186:200-206 (2015) (IF=4.529)