个人介绍

陈雪瑞，2019年毕业于浙江大学获得理学博士学位，同年进入上海大学医学院任讲师。至今已在ACS Appl. Mater. Interfaces, Biomater. Sci., ACS Biomater. Sci. Eng., Langmuir, RSC Adv., Colloid. Surface. B., Colloid. Surface. A., Oncol. Rep.等SCI收录的期刊上发表10篇论文。


主要研究领域
1.肿瘤微环境响应型纳米递药系统的构建与靶向功能修饰；
2. 抗肿瘤药物的靶向释放与协同治疗；
3. 生物热力学及微量热学。


代表性学术成果
论文
1. Chen, X.R.; Tong, R.L.; Shi, Z.Q.; Yang, B.; Liu, H.; Ding, S.P.; Wang, X.; Lei, Q.F.; Wu, J.^*; Fang, W.J^*. MOF Nanoparticles with Encapsulated Autophagy Inhibitor in Controlled Drug Delivery System for Antitumor. ACS Appl. Mater. Interfaces, 2018, 10 (3), 2328-2337.（高被引论文）
2. Chen, X.R.^#; Tong, R.L.^#; Liu, B.B.; Liu H.; Feng X.D.; Ding, S.P.; Lei, Q.F.; Tang, G.P.; Wu, J.^*; Fang, W.J.^* Duo of (–)-Epigallocatechin-3-Gallate and Doxorubicin Loaded by Polydopamine Coating ZIF-8 in Regulation of Autophagy for Chemo-Photothermal Synergistic Therapy. Biomater. Sci., 2020, 8(5), 1380-1393.
3. Chen, X.R.; Shi, Z.Q.; Tong, R.L.; Ding, S.P.; Wang, X.; Wu, J.; Lei, Q.F.^*; Fang, W.J.^* Derivative of Epigallocatechin-3-gallatea Encapsulated in ZIF-8 with Polyethylene Glycol–Folic Acid Modification for Target and pH-Responsive Drug Release in Anticancer Research. ACS Biomater. Sci. Eng. 2018, 4 (12), 4183-4192.
4. Chen, X.R.; Zhang, L.; Ding, S.P.; Lei, Q.F.^*; Fang, W.J.^* Cisplatin Combination Drugs Induce Autophagy in HeLa Cells and Interact with HSA via Electrostatic Binding Affinity. RSC Adv., 2017, 7, 22270-22279.
5. Shi, Z.Q.; Chen, X.R.; Zhang, L.; Ding, S.P.; Wang, X.; Lei, Q.F.^*; Fang, W.J.^* FA-PEG Decorated MOF Nanoparticles as a Targeted Drug Delivery System for Controlled Release of an Autophagy Inhibitor. Biomater. Sci. 2018, 6, 239-240.
6. Zhang, S.S.; Chen, X.R.; Yu, J.; Hong, B.Y.; Lei, Q.F.^*; Fang, W.J.^* Hydrophobic Fractal Surface from Glycerol Tripalmitate and the Effects on C6 Glioma Cell Growth. Colloid. Surface. B. 2016, 142, 377-384.
7. Zhang, S.S.; Chen, X.R.; Ding, S.P.; Lei, Q.F.^*; Fang, W.J.^* Unfolding of Human Serum Albumin by Gemini and Single-chain Surfactants: A Comparative Study. Colloid. Surface. A. 2016, 495, 30-38.
8. Zhang, L.; Chen, X.R.; Wu, J.Z.; Ding, S.P.; Wang, X.; Lei, Q.F^*.; Fang, W.J.^* Palladium Nanoparticles Induce Autophagy and Autophagic Flux Blockade in Hela Cells. RSC Adv., 2018, 8, 4130.
9. Chen, Y., Zhuang, H.F., Chen, X. R., Shi, Z. Q., Wang, X.^*, Spermidine-induced Growth Inhibition and Apoptosis via Autophagic Activation in Cervical Cancer. Oncol. Rep. 2018, 39(6), 2845-2854.
10. Zhang, S.S.; Ding, S. P., Yu, J.; Chen, X.R.; Lei, Q.F.^*; Fang, W.J.^* Antibacterial Activity, in Vitro Cytotoxicity, and Cell Cycle Arrest of Gemini Quaternary Ammonium Surfactants. Langmuir, 2015, 31(44), 12161-12169.





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