姓名：季朝能
出生年月：1970.8
职称：副教授
联系地址：复旦大学生命学院生物二楼118室
联系电话：65648488
E-mail地址: chnji@fudan.edu.cn
简历：
主要经历： 1998年8月-- 至今 复旦大学遗传所工作，主要从事蛋白质三维结构与功能关系、人基因功能的研究。
1995年8月-- 1998年6月 于复旦大学遗传所攻读博士学位，主要从事耐热逆转录酶的应用工作和耐热酶的热稳定机制的研究。
1992年8月-- 1995年6月 于复旦大学遗传所攻读硕士学位，主要从事DNA聚合酶复制精确性的研究。
1988年9月-- 1992年7月 于复旦大学遗传及遗传工程系攻读学士学位。
主要科研经历：
参加过"863基因工程支撑技术"、自然科学基金重点项目"极端环境下细菌的资源分类及分子生物学的研究"、国家自然科学基金"耐热碱性磷酸酯酶的热稳定性和热激活机制研究"等课题的研究。独立主持完成了校青年科学技术基金"耐热碱性磷酸酯酶的晶体结构测定和热稳定机制的研究"；国家自然科学基金"耐热邻苯二酚2，3双加氧酶的反常散射法的晶体结构研究"；上海市青年科技启明星计划"人基因编码蛋白激酶的功能结构分析"；上海市科学技术发展基金"贵州省少数民族重要缺陷发生的影响因素及防治研究"；国家科技攻关计划西部开发重大项目课题"贵州省少数民族重要缺陷发生的影响因素及防治研究"。目前主持国家自然科学基金"人GMP还原酶的晶体结构测定和催化机制的研究"；自然科学基金重大项目子课题"嘌呤代谢相关酶的晶体结构研究"；横向项目"与人类健康相关的蛋白质结构和医学成像的同步辐射研究"；参与了国家863项目"糖尿病相关基因的克隆和功能研究"；国家重点基础研究发展计划子课题"人类肝脏结构蛋白质组学研究"；上海市科学技术发展基金"砷与肿瘤发生和细胞凋亡相关基因的克隆及功能研究"

主要研究方向：
结构生物学，医学与分子遗传学

获奖情况：
2001年获得上海市青年科技启明星计划的支持

代表性论文和专著：
至2004年底，共发表论文90多篇，其中SCI论文60篇，主要的论文如下：
1．姜涛，季朝能，盛小禹，民勤，谢毅，龚为民，毛裕民. 应用多波长反常散射法测定耐热邻苯二酚2，3-双加氧酶的晶体结构. (2001) 科学通报，46：1876-1879
2．Jiang Tao, Ji Chao-neng, Sheng Xiao-yu, Bai Xiao-yang, Mao Yu-min. Expression, purification and preliminary X-ray diffraction analysis of the mutant Pro229Ser of thermostable catechol 2,3-dioxygenase. (2001) Acta Biochimica et Biophysica Sinica（生物化学与生物物理学报）， 33(5):569-572
3．Chao-Neng Ji, Tao Jiang, Min-Qin Chen, Xiao-Yu Sheng, Yu-Min Mao*. purification, crystallization and preliminary X-ray diffraction studies on the thermostable alkaline phosphatse from thermus sp.3041 expressed in Esherichia coli. (2001) Acta Cryst. D57:614-615
4．Linsen Dai, Chaoneng Ji, Dacao Gao, Jian Wang, Xiaoyu Sheng, Yumin Mao，Modeling and Analysis of the Structure of the Thermostable Catechchol 2,3-Dioxygenase from Bacillus Stearothermophilus. (2001) J BIOMOL STRUCT DYN，19(1):75-83
5．Tao Jiang, Chao-Neng Ji, Xiao-Yu Sheng, Yi Xie and Yu-Min Mao, Characterization and Preliminary X-ray Diffraction Analysis of the Mutant Pro229Ser of thermostable Catechol 2,3 Dioxygenase.（2001）Protein and Peptide Letters，8(4):327-332
6．Chao-Neng Ji, Zai-Long Cai, Gen-Tao Cao, Gang Yin, Bing-Hua Jiao, Tao Jiang, Guang Shu, Ji-Fang Mao, Yi Xie, Yu-Min Mao, PURIFICATION, CRYSTALLIZATION AND PRELIMINARY X-RAY STUDIES OF HUMAN AUGMENTER OF LIVER REGENERATION. （2002）Protein Peptide Letters, 9(6): 553-556
7．Jian Xu, Chaoneng Ji, (two authors to be equal) Liu Wang, Yueqiong Cao, Jianliang Dai,, Xin Ye, Li Zeng, Jianfeng Dai, Qihan Wu, Yi Xie, Yumin Mao. Cloning and expression of a novel human C5orf12 gene, a member of the TMS_TDE family. （2003）Molecular Biology Reports，30 (1): 47-52
8．Chaoneng Ji, Jinzhong Chen, Yi Xie, Shu Wang, Qian Ji, Enpeng Zhao, Wei Jin, Xiaozhou Wu, Wanxiang Xu, Kang Ying, Yumin Mao. A novel cDNA encodes a putative hRALY-like protein, hRALYL.（2003）Molecular Biology Reports, 30 (1): 61-67
9．Xiaohua Ni, Chaoneng Ji(two authors to be equal), Gentao Cao, Haipeng Cheng, Lingchen Guo, Shaohua Gu, Kang Ying, Robert Chunhua Zhao and Yumin Mao. Molecular cloning and characterization of the protein 4.1O gene, a novel member of the protein 4.1 family with focal expression in ovary. （2003）J Hum Genet，48(2):101-106
10．Chao-Neng Ji, Gang Ying, Ying-Feng Deng, Shu Chen, Wen-Hong Zhang, Guang Shu, Yi Xie, Yu-Min Mao. Purification, crystallization and preliminary X-ray studies of GMP reductase 2 from human，（2003）Acta Cryst.，D59, 1109-1110
11．Xin Ye, Chaoneng Ji(two authors to be equal), Qingshan Wang, Chao Cheng, Rong Tang, Jian Xu, Li Zeng, Jianfeng Dai, Qihan Wu, Shaohua Gu, Yi Xie, Yumin Mao. Isolation and characterization of a novel human putative receptor protein kinase gene STYK1. （2003）Molecular Biology Reports, 30: 91-96.
12．Jianfeng Dai, Chaoneng Ji, (two authors to be equal) Shaohua Gu，Qihan Wu, Liu Wang, Jian Xu, Li Zeng, Xin Ye, Gang Yin, Yi Xie, and Yumin Mao，Cloning and sequence analysis of the human cDNA encoding the synaptoporin (Δ), a highly conservative synaptic vesicle protein.（2003）Molecular Biology Reports，30(3):185-191
13．Chao-Neng Ji, Liang Tian, Cong-Jing Feng, Gang Yin, Guang Shu, Ji-Xi Li, Wei-Ming Gong, Hai Pang, Yi Xie, Yu-Min Mao. purification, crystallization and preliminary x-ray studies of a p-nitrophenylphospgatase from bacillus stearothermophilus,（2003）Protein Peptide Letters, 10(5):521-524
14．Liu Wang, Chaoneng Ji(two authors to be equal), Hai Wu, Jian Xu, Qihan Wu, Jianfeng Dai, Gang Yin, Yin Ye, Shaohua Gu, Yi Xie, Yumin Mao； Identification and expression analysis of a novel splice variant of human Sprouty1 gene. （2003）International Journal of Molecular Medicine, 12 (5): 783-787
15．Lingchen Guo, Chaoneng Ji, (two authors to be equal) Shaohua Gu, Kang Ying, Haipeng Cheng, Xiaoghua Ni, Jianping Liu, Yi Xie and Yumin Mao Molecular cloning and characterization of a novel human kinase gene, PDIK1L. （2003）Journal of Genetics, 82(1,2):27-32
16．Feng Jin, Chaoneng Ji, (two authors to be equal) Lingfeng Liu, Jianfeng Dai, Shaohua Gu, Xianfei Sun, Yi Xie,Yumin Mao.Molecular cloning and characterization of a novel human protein phosphatase 2C cDNA (PP2Cε*).（2004）Molecular Biology Reports. 31: 197-202
17．Rong Jin，Linsen Dai，Jinbiao Zheng，Chaoneng Ji . Purification and structural study of the β form of human cAMP-dependent protein kinase inhibitor. （2004）Eur.J.Biochem, 271:1768 -1773