基本信息
职称：副研究员
电话：
邮箱：yaoyu@fudan.edu.cn
地址：复旦大学生命科学学院E501-2室



个人简介
男，1978年出生，博士，副研究员。
2000年获复旦大学微生物学学士学位， 2006年，获复旦大学遗传学博士学位。2006-2011年在美国纽约州立大学石溪分校从事博士后研究。2011年7月任复旦大学生命科学学院副研究员。
Male, born in 1978, Ph.D., associate researcher.
B.A degree in Microbiology from Fudan University in 2000, and Ph. D. in Genetics from Fudan University in 2006. Postdoctroal associate at SUNY Stony Brook from 2006 to 2011. Associate Researcher at Fudan University since June, 2011.
主要研究方向 (Research Interests)
以酵母为模式生物，利用表观遗传，分子遗传和生物化学等手段，研究表观遗传调控在维持基因组稳定性中的作用。
Using yeast as model organism, study the regulation of genomic stability, by epigenetic, molecular genetic and biochemical approaches.
获奖情况 (Awards)
2016, 第二届上海高校青年教师教学竞赛（自然科学基础学科）一等奖, 上海市教学能手
代表性成果
1. Yu, Y*†., Zhou, H†., Deng, X., Wang, W. & Lu, H. (2016) Set3 contributes to heterochromatin integrity by promoting transcription of subunits of Clr4-Rik1-Cul4 histone methyltransferase complex in fission yeast, Sci Rep. 6, 31752.
2. Zhou, H., Liu, Q., Shi, T., Yu, Y*. & Lu, H. (2015) Genome-wide screen of fission yeast mutants for sensitivity to 6-azauracil, an inhibitor of transcriptional elongation, Yeast. 32, 643-55.
3. Deng, X., Zhou, H., Zhang, G., Wang, W., Mao, L., Zhou, X., Yu, Y#. & Lu, H#. (2015) Sgf73, a subunit of SAGA complex, is required for the assembly of RITS complex in fission yeast, Sci Rep. 5, 14707.
4. Lei, B†.., Zhou, N†.., Guo, Y., Zhao, W., Tan, Y. W., Yu, Y#. & Lu, H#. (2014) Septin ring assembly is regulated by Spt20, a structural subunit of the SAGA complex, J Cell Sci. 127, 4024-36.
5. Pan, X†., Lei, B†., Zhou, N., Feng, B., Yao, W., Zhao, X., Yu, Y#. & Lu, H#. (2012) Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library, BMC Genomics. 13, 662.
6. Li, Y†., Yu, Y†., Zhang, Y†., Zhou, Y., Li, C., Zhu, J., Yuan, H. & Lu, H*. (2011) MAFIP is a tumor suppressor in cervical cancer that inhibits activation of the nuclear factor-kappa B pathway, Cancer Sci. 102, 2043-50.
7. Yu, Y., Srinivasan, M., Nakanishi, S., Leatherwood, J., Shilatifard, A. & Sternglanz, R*. (2011) A conserved patch near the C terminus of histone H4 is required for genome stability in budding yeast, Mol Cell Biol. 31, 2311-25.
8. Kumar, P. R., Yu, Y., Sternglanz, R., Johnston, S. A. & Joshua-Tor, L*. (2008) NADP regulates the yeast GAL induction system, Science. 319, 1090-2.