梁建英

药物分析学, 教授, 硕士生导师



姓名
梁建英
性别
女

职称
教授
学历
硕士

电话

传真


电子邮件
jyliang@shmu.edu.cn
个人主页


通讯地址
上海市浦东新区张衡路826号科研楼521室


教育经历
1984.09 – 1988.07 华东理工大学化学系，本科1988.09 – 1991.07 华东理工大学化学系，硕士


工作经历
1991.07 – 2002.12 上海医科大学药学院，讲师
2002.12 – 2015.12 复旦大学药学院，副教授
2015.12 – 至今 复旦大学药学院，教授


承担科研项目情况
1.国家自然科学基金面上项目, 荧光仿生膜技术研究中药活性成分的细胞膜通透性，（**）2.上海市科委中药现代化项目，中成药大品种的药效物质基础研究，（08DZ**）
3.上海市科委科技支撑项目一项，长效抗肿瘤药物雷公藤红素的临床前研究，（**）
4.“重大新药创制”中的抗艾滋病病毒新药临床评价研究技术平台建设子课题五-药物代谢组研究，（2012ZX**-005）


研究方向
1. 药物分析新技术2. 生物样品前处理技术及新药质量标准
3. 中药活性成分筛选新技术



代表性论著
1. Li MH; Zhu RR; Song XX; Wang ZJ; Weng HB; Liang JY*(梁建英). A sensitive method for the quantification of short-chain fatty acids by benzyl chloroformate derivatization combined with GC-MS, Analyst, 2020, DOI: 10.1039/D0AN00005A
2.Xue Y,Liang JY*(梁建英).Chinese hamster ovary-sphingomyelin synthase2 biospecific extraction and liquid chromatography with tandem mass spectrometry analysis for the prediction of bioactive components of Rhizoma Polygoni Cuspidati. Journal of Separation Science.2016,39, 1067–1072.
3. Ma R,Weng HB,Liang JY *(梁建英). Screening of lipase inhibitors in Folium Mori with lipase-linked magnetic microspheres by high-performance liquid chromatography and evaluation in diabetic mice Journal of Separation Science.2016,39, 4474–4483
4. Feng XY, Gao XL, Kang T, Jiang D, Yao JH, Jing YX, Song QX, Jiang XG, Liang JY*(梁建英), Chen J. Mammary-Derived Growth Inhibitor Targeting Peptide-Modified PEG-PLA Nanoparticles for Enhanced Targeted Glioblastoma Therapy. Bioconjugate Chem. 2015, 26, 1850-1861.
5. Deng YC,Liu R,Yang P,Liang JY*(梁建英). Rapid identification of efavirenz metabolites in rats and humans by ultra high performance liquid chromatography combined with quadrupole time-of-flight tandem mass spectrometry. Journal of Separation Science.2015,38, 1529–1536.
6. Xue Y,Liang JY*(梁建英). Screening of bioactive compounds in Rhizoma Polygoni Cuspidati with hepatocyte membranes by HPLC and LC-MS. Journal of Separation Science.2014,37(3), 250–256.
7. Ren YL, Liu TSh, Song GX, Hu YM, Liang JY *(梁建英). Determination of lomerizine in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study. Journal of Chromatography B.2014, 947-948, 96–102.
8. Liu JC, Lu Y, Liang, JY*(梁建英). A novel fluorescence derivatization method combined with HPLC for determining the activities of endogenous caspase. Analyst. 2012, 137, 5097–5104.
9. Chen XP, Deng YC, Xue Y, Liang JY*(梁建英). Screening of bioactive compounds in Radix Salviae Miltiorrhizae with liposomes and cell membranes using HPLC. Journal of Pharmaceutical and Biomedical Analysis.2012,70,194-201.
10. Chen XP,Xia YQ, Lu Y, Liang JY*(梁建英). Screening of permeable compounds in Flos Lonicerae Japonicae with liposome using ultrafiltration and HPLC. Journal of Pharmaceutical and Biomedical Analysis 2011,54,406-410.
11. Zhou LJ,Chen XP, Gu YQ, Liang JY*(梁建英).Transport Characteristics of Candesartan in Human Intestinal Caco-2 Cell Line, Biopharmaceutics & drug disposition.2009,30,259-264.
12. Zhou LJ,Gu LH, Wang YJ, Liang JY*(梁建英). Determination of bifendate in human by HPLC-MS and bioequivalance on bifendate pills in healthy volunteers，Journal of Pharmaceutical and Biomedical Analysis.2006,40,1025-1030.