Denise Wootten


聘期:2018.03-2021.03



姓名
Denise Wootten
性别


职称

学历


电话
61-3-9903-9088
传真


电子邮件
denise.wootten@monash.edu
个人主页


通讯地址



个人简历

Denise Wootten博士是从事B类G蛋白偶联受体研究的青年科学家，也是该领域新兴的引领者。其研究的主要目的在于深入了解这些受体的结构和功能，致力于寻找药物发现的新方法。她的研究兴趣包括偏向激动机理、受体与调节辅助蛋白相互作用、变构调节及其结构与机制基础。她的研究还涉及结构与体外药理学和信号转导之间的联系以及受体激活后在体内产生的生理效应。
Dr. Denise Wootten is an early career scientist and an emerging leader in the study of class B G protein-coupled receptors. The principle focus of her research is directed towards a deeper understanding of the structure and function of these receptors in an effort to identify novel approaches to drug discovery. Her research interests encompass biased agonism, interaction of receptors with regulatory accessory proteins, allosterism and the structural and mechanistic basis of these paradigms. She is also addressing the links between structure, in vitro pharmacology and signal transduction with the physiological effects elicited in vivo following activation of these receptors.