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复旦大学生命科学学院研究生导师简介-张志鸿

复旦大学 免费考研网/2013-01-17

张志鸿
发布时间:2010-09-21浏览次数:次
姓名:张志鸿
出生年月:1940年1月
职称:教授
联系地址:复旦大学生命科学学院
联系电话:(86-21)65643673,65643924,65642810,(FAX)(86-21)65650149
E-mail地址:zhzhang@fudan.edu.cn

简历:
1963年毕业于复旦大学生物物理学专业;
1979-1981年日本京都大学访问学者;
1988年获日本京都大学理学博士学位;
1990-1991年美国哈佛医学院高级访问学者;
1991年至今为复旦大学生命科学学院生理学和生物物理学系教授;
1994-2002年任中国生物物理学会副理事长;
1996-2000年任复旦大学生命科学学院副院长;
2000年至今为上海生物物理学会理事长

主要研究方向:
(1)红细胞膜上带3蛋白和葡萄糖转运蛋白的转运特性,生物膜上蛋白质相互作用对物质转运的调控;
(2)生物膜上离子通道特性,特别是机械敏感性离子通道功能的调控机理;
(3)膜蛋白的结构生物学,目前主要研究带3蛋白胞质段与带4.2间的相互作用;
(4)用蛋白质组学技术研究糖尿病患者红细胞膜蛋白质组的异常;
(5)失神经肌肉萎缩的蛋白质组学研究。

代表性论文和专著:

1.张志鸿,刘文龙(1987),“膜生物物理学”,高等教育出版社。

2.Zhi-hongZhangandA.K.Solomon(1992),EffectofpCMBSonAnionTransportinHumanRedCellMembraneBiochim.Biophys.Acta1106:31-39.

3.ZhouHan-qingandZhangZhi-hong(1994),TheMeasurementofAnionPermeabilitybyHemolyticKineticsoftheRedCells,Chin.J.Biochem.Biophys.26:119-126.

4.PengFengandZhangZhihong(1996),EffectofDIDSontheFunctionofGlucoseTransportProteininRedCellMembranes,Chin.Sci.Bull.40:68-72.

5.MinqinChen,ChangchuanYin,WeiZhang,YuminMao,andZhihongZhang(1998),Purification,CrystallizationandPreliminaryX-RayDiffractionStudiesontheThermostableCatechol2,3-dioxygenaseofBacillusstearothermophilusExpressedinEscherichiacoliActaCrystallgraphicaD54:446-447.

6.Xiao-jianHu,FengPeng,Han-qingZhou,Zhi-hongZhang,Wei-yingChengandHang-fangFeng(2000),TheAbnormalityofGlucoseTransporterintheErythrocyteMembraneofChineseType2DiabeticPatients,Biochim.Biophys.Acta1466:306-314.

7.Y.A.Mei,M.M..Wu,C.L.Huan,J.T.Sun,H.Q.Zhou,Z.H.Zhang(2000),4-Aminopyridine,aSpecificBlokerofK+Channels,InhibitedInwardNa+CurrentinRatCerebellarGranuleCells,BrainRes.873:46-53.

8.WeiHua,MeiYan-Ai,WuMing-ming,SunJia-ting,ZhouHan-qing,ZhangZhi-hong(2000),Swelling-activatedchloridecurrentsinembryonicchickheartcells,
ActaPharmacolSin21(11):986-990.

9.Y.A.Mei,P.P.N.Lee,H.Wei,Z.H.ZhangandS.F.Peng(2001),Melatoninanditsanalogspotentiatethenifedipine-sensitivehigh-voltage-activatedcalciumcurrentinthechick
embryonicheartcells,J.PinealRes30:13-21.

10.张志鸿(2001),新世纪推动生物科学发展的“Bio-X”,生物物理学报17(1):1-9.

11.TANGLin,SUNQing'an,LIQingguo,HUANGYibo,WEIQingqing,ZHANGYi,HUJun,ZHANGZhihong,LIMinqian&YANGFujia(2001),imagingbacteriorhodopsin-likemoleculesofclaret-membranesfromTibet
halobacteriaxz515byatomicforcemicroscope,ChineseScienceBulletin46(22):1897-1900.

12.LiY-Z,ZhouH-Q,PengFandZhangZ-H(2001),Effectonglucosetransportand
anionexchangeinhumanerythrocytesbymechanicalforcefactors,ActaBiochim.Biophys.Sinica33(5):489-496.

13.HUANChun-lei,ZHOUMi-ou,WUMing-ming,ZhangZhi-hong,MEIYan-ai(2001),ActivationofmelatoninreceptorincreasesadelayedretifierK+currentinrat
cerebellargranulecells,BrainResearch917:182-190.

14.JIANGWeihua,DINGYu,HUXiaojian,PENGFeng,ZHOUHanqing&ZHANGZhihong(2002),Effectonmembranetransportintheerythrocytesbyband3cross-linking,ChineseScienceBulletin47(22):1889-1892.

15.HuaWEI,YanAiMEI,JiaTingSUN,HanQingZHOU,ZhiHongZhang(2003),Regulationofswelling-activatedchloridechannelsinembryonicchickheartcells,CellResearch13(1):21-28.

16.MingJiang,LinzhiJia,WeihuaJiang,XiaojianHu,HanqingZhou,XinGao,ZhiqiangLu,andZhihongZhang(2003),Proteindisregulationinredbloodcellmembranesoftype2diabeticpatients,Biochem.Biophys.Res.Commun.309:196-200.

17.YuDing,WeihuaJiang,YangSu,HanqingZhou,andZhihongZhang(2004),Expressionandpurificationofrecombinantcytoplasmicdomainofhumanerythrocyteband3withhexahistridinetagorchitin-bindingtaginEscherichiacoli.,ProteinExpress.Purif.34:167-175.

18.LinzhiJia,LeiXu,MingJiang,YudongGu,andZhihongZhang(2005),Proteinabnormalityindenervatedskelatalmusclesfrompatientswithbrachialinjury,Microsurgery25(4):316-321.

19.YuDing,MingJiang,WeihuaJiang,YangSu,HanqingZhou,XiaojianHu,andZhihongZhang(2005),Expression,purification,andcharacterizationofrecombinanthumanflotillin-1inEscherichiacoli.ProteinExpress.Purif.42:137-145.

20.张志鸿,"同步辐射应用概论"(马礼敦,杨福家主编,2001年第一版,2005年第二版),第十二章"同步辐射在生命科学中的应用",复旦大学出版社。.

21.张志鸿(2005),"生物膜"(杨福愉主编)第七章"生物膜蛋白质组学",科学出版社。

22.WeihuaJiang,YuDing,YangSu,MingJiang,XiaojianHu,ZhihongZhang(2006),Interactionofglucosetransporter1withanionexchanger1invitro,Biochem.Biophys.Res.Commun.339:1255-1261.

23.YangSu,YuDing,MingJiang,WeihuaJiang,XiaojianHuandZhihongZhang(2006),Associationsofprotein4.2withband3andankyrin,Mol.Cell.Biochem.289:1255-1261.

24.MingJiang,YuDing,YangSu,XiaojianHu,JinyingLi,ZhihongZhang(2006),Arginase-flotillininteractionbringsarginasetoredcellmembrane,FEBSLett.580:6561-6564.

25.YangSu,YuDing,MingJiang,XiaojianHu,ZhihongZhang(2007),Protein4.2Komatsu(D175Y)associatedwiththelackofinteractionwithankyrininhumanredbloodcells,BloodCell.Mol.Dis.(Epubaheadofprint,2006)



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