殷瑞雪
E-mail:yinruixue@ecust.edu.cn
职位:
职称:讲师

个人简介:
2016.4-今 华东理工大学机械与动力工程学院 讲师；
2016.6-2018.6 加拿大萨斯喀彻温大学机械工程/生物医学工程系 博士后；
2013.9-2016.3 华东理工大学机械与动力工程学院 师资博士后；
2008.9-2013.7 北京化工大学材料科学与工程学院 博士。

联系方法:
地址：上海市徐汇区梅陇路130号华东理工大学实验14楼209
电话：
研究方向1. 面向生物医学应用的智能器件设计及控制
包括机电-化学复合人工胰腺系统、胰岛素持久输送系统、糖尿病个性化给药系统、BioMEMS葡萄糖传感器等。
2. 软体/微纳米机器人技术
以非接触控制技术为手段（如光控制、磁控制），开发智能驱动软体/微纳米机器人用于生物医疗（如磁控制药物输送纳米机器人） 。
3. 微流控、3D打印等先进制造技术在生物医学领域的应用
基于微流控液滴制备技术、细胞捕获技术开发生物医用芯片；以生物3D打印、光固化3D打印、微纳3D打印技术为手段保障智能器件及软体/微纳米机器人的加工成型。

承担科研项目国家及省部级项目：
[1] 葡萄糖响应性单分散核壳结构微球用于可调控胰岛素递送的研究，国家自然科学基金青年基金项目 (项目负责人，已结题)
[2] 3D打印包埋载体的药物支架用于持续性胰岛素自调节递送, 中央高校基本科研业务费探索研究专项 （项目负责人，已结题）
[3] 微流体制备葡萄糖/光双响应核壳微球用于胰岛素递送,中国博士后科学基金面上项目（项目负责人，已结题）
获奖成果代表性著作发表SCI收录英文科技论文三十余篇(第一作者／通讯作者发表论文十余篇)，其中中科院I区、II区论文十五篇，影响因子5以上十篇，总被引次数482次，h指数11；申请中国发明专利十余项（第一发明人三项），授权四项。
近五年代表性期刊论文：
1.Ruixue Yin*, MeirongBai, JingHe, JunNie, WenjunZhang*. Concanavalin A-sugar affinity based system: Binding interactions, principle of glucose-responsiveness, and modulated insulin release for diabetes care.International Journal of Biological Macromolecules, 2019, 124, 724-732.
2. Ruixue Yin*, Jing He, Meirong Bai, Cong Huang, Kemin Wang*, Hongbo Zhang, Shih-Mo Yang, W.J. Zhang.Engineering Synthetic Artificial Pancreas Using Chitosan Hydrogels Integrated with Glucose-Responsive Microspheres for Insulin Delivery,Materials Science and Engineering: C, 2019，96，374-382.
3. Meirong Bai, Jing He, Liangfa Kang, Jun Nie,Ruixue Yin*. Regulated basal and bolus insulin release from glucose-responsive core-shell microspheres based on Concanavalin A-sugar affinity,International Journal of Biological Macromolecules, 2018, 113, 889-899.
4.Ruixue Yin*,Nan Zhang, Kemin Wang*, Hongyu Long, Tianlong Xing, Jun Nie, Hongbo Zhang.Material Design and Photo-regulated Hydrolytic Degradation Behavior ofTissue Engineering Scaffolds Fabricated via 3D Fiber Deposition,Journal of Materials Chemistry B, 2017, 5, 329-340.
5.Ruixue Yin, Nan Zhang, Wentao Wu, Kemin Wang*. Poly (ethylene glycol)-grafted cyclic acetals based polymer networks with non-water-swellable, biodegradable and surface hydrophilic properties.Materials Science and Engineering: C, 2016, 62: 137-143.
6.Ruixue Yin, Wentao Wu, Kemin Wang*, Wen Jun Zhang*. In-situ dispersed photopolymerization of cyclic acetals/hydroxyapatite composites: Effects of the content of hydroxyapatite.Materials Science and Engineering: C, 2015, 46: 239-245.
7.Ruixue Yin, Yuhui Lu, Kemin Wang*, Jun Nie. Macroporous crosslinked polymers with controlled structure fabricated via low-temperature phase-separation photopolymerization.Macromolecular Materials and Engineering, 2015, 300: 291-298.
8 Ruixue Yin, Kemin Wang, Shuang Du, Lu Chen, Jun Nie*, Design of genipin-crosslinked microgels from concanavalin A and glucosyloxyethyl acrylated chitosan for glucose-responsive insulin delivery.Carbohydrate polymers, 2014, 103(2): 369-376.
会议论文：
1. Ang Chen,Ruixue Yin, Lin Cao, Chenwang Yuan , Soft Robots: Concept and Research Directions, 24th International Conference on Mechatronics and Machine Vision in Practice (M2VIP) , Auckland, New Zealand, November 21-23, 2017.
2. Jing He, Meirong Bai, Cong Huang，Ruixue Yin*，Design of Artificial Pancrease with Self-regulated and Prolonged Insulin Release Behavior, The 6th International Conference on Biomedical Engineering and Biotechnology (ICBEB 2017), Guangzhou, China, October 17-20,2017.
3. Chenwang Yuan, Ge Chen,Ruixue Yin, A New Under-Actuated Resilient Robot, IEEE International Conference on Systems, Man and Cybernetics (SMC), Banff, Canada, October 5-8, 2017.
4.R.X. Yin*, M.R. Bai, B. Zhang, K.M. Wang, H.B. Zhang, S.M. Yang, W.J. Zhang*, J.W. Wang. Understanding Drug Delivery from a System Perspective: Concept and Demonstration. The 12th Annuel IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), April 9-12, 2017, Los Angeles, USA.
5. Fengjuan Chen, Guanru Du, Di Yin,Ruixue Yin, Hongbo Zhang, Shih-Mo Yang*, Crystallization of Bovine Insulin on a Flow-free Droplet-based Platform, International Conference on Engineering Materials, Energy, Management and Control. Xi’an, China, March 11-12, 2017.
6. C. Huang, H.B. Zhang, Jing He, Katharina K. C. Koch,R.X. Yin, W.J. Zhang*. A novel micro-fluidic approach to produce controllable gas-in-liquid-in-liquid double emulsions. SPIE BiOS, January 28 - February 2, 2017, San Francisco, USA.
7.Ruixue Yin*, Kemin Wang, Hongbo Zhang, Nan Zhang. Photo-regulated insulin delivery from glucose-responsive core-shell microspheres prepared by two-step high-speed shear-emulsions. 10^thWorld Biomaterials Congress, May 17-22, 2016, Montreal, Canada
8. L. Fu,R.X. Yin, X.J. Wang, T. Zhang, Ang Chen, E.M. Zhang, W.J. Zhang*. The folding system: its concept and classification. International Conference on Advanced Materials and Engineering Structural Technology (ICAMEST 2015), April 25-26, 2015, Qingdao, China