牟伯中




牟伯中，工学博士、教授、博士生导师 (生物化工、应用化学、物理化学)
应用化学研究所 所长，生物采油教育部工程研究中心 主任
Appl. Environ. Biotech. (2015-) 、微生物学杂志 (2004-) 等刊物编委
中石化采油表面活性剂重点实验室、微生物采油重点实验室等学术委员会委员
享受国务院政府特殊津贴，第十一届、十二届上海市政协委员

实验室地址：实验三楼225室
联系电话:
Email: bzmu@ecust.edu.cn
欢迎化学、微生物学、生物技术及相关专业的学生报考。

主要研究方向及成果:
主要从事生物采油基础与应用技术方面的研究工作，包括 (1) 生物表面活性剂及生物基表面活性剂的结构与性能，(2) 石油烃厌氧生物降解产甲烷途径与生物标志物，以及 (3) CO2生物转化途径与调控机制。近年来负责承担国家重点研发计划专项、国家863计划重点、国家自然科学基金重点、上海市基础研究重点项目及国际合作研究等多项重点科研任务。在国际学术刊物发表论文 (SCI) 130余篇，申请发明专利40余项 (其中授权专利31项)，已经实现转让和产业化的专利技术产生了显著的经济与社会效益。作为第一完成人获得国家科技进步二等奖 (2010) 及上海市科技进步一等奖 (2008) 等科研成果奖。

教学方面，主讲本科生《物理化学》课程和研究生《生物物理化学》等课程。先后承担国家首批双语教学示范课程 “《物理化学》双语教学示范课程” 和教育部 “工科化学系列课程双语教学体系的研究与建设” 等教学研究项目。曾获宝钢优秀教师奖、国家教学成果二等奖 (2005)、上海市教学成果一等奖 (2005) 和华东理工大学教学成果一等奖 (2008) 等教学成果奖。

近五年主持的主要科研项目：
国家重点研发计划专项项目(课题编号：2017YFB**，起止时间：2017-2021)
国家自然科学基金重点项目 (项目编号：**，起止时间：2016-2020)
上海市基础研究重点项目 (项目编号：15JC**，起止时间：2015-2018)
国家863计划重点项目 (项目编号：2009AA063503，起止时间：2009-2011)
国家自然科学基金面上项目 (项目编号：**，起止时间：2012-2015)
国家自然科学基金面国际 (地区) 合作项目 (项目编号：, 起止时间：2012-2014)

Dr. Bo-Zhong Muis a professor and the head of Institute of Applied Chemistry, East China University of Science and Technology (ECUST), and the director of the Engineering Research Center for Microbial Enhanced Oil Recovery, the Ministry of Education, China.
Dr. Bo-Zhong Mu joined the East China University of Science and Technology as a full professor in the January 2001, where he heads a group in the interdisciplinary area of Microbial Enhance Oil Recovery. These interdisciplinary studies have been supported by the National Natural Science Foundation of China, the National High-Tech Research and Development Program, the International Joint Research programs, and by the industrial partners of PetroChina and SINOPEC. He has actively joined in the collaborative research with domestic and international communities.
He once worked at the laboratory for geodrilling fluid chemistry, China Coal Research Institute (Xian) after his graduation from Chengdu University of Technology in 1982 till 1995, where he was involved in studies of complex colloidal systems in geodrilling engineering, and received his M.S. degree in 1989. He studied Applied Chemistry, in particular, the interfacial chemistry of porous media and fundamentals for enhanced oil recovery at the state key laboratory headed by Academician Pingya Luo in the Southwest Petroleum University. After receiving his Ph.D. in Applied Chemistry in 1998, he moved to the Ocean University of Qingdao for his postdoctoral research, and to the University of Wyoming (Wyoming, USA, 1999) for the research in microbial enhanced oil recovery (MEOR).
His Research interests focus on the chemical & biological fundamentals for enhanced oil recovery, including interfacial behavior & microbial transport in porous media, bio-based surfactants & their molecular aggregates, and molecular microbial community & biodegradation in petroleum reservoirs. His interests also lie in the extension of the research to application with industrial partners, covering MEOR, the methanegenic production from residue oil, and CO2 biofixation in situ oil reservoirs. Since joining ECUST in 2001, He has published more than 130 peer-reviewed articles, and was awarded the First Class Prize of Shanghai Science and Technology Progress Award in 2008 and the Second Class Prize of National Science and Technology Progress Award in 2010.
Teaching duties involve a number of Chemistry and Biotechnology classes at BSc, MSc and PhD levels, including the courses of Physical Chemistry, Biophysical Chemistry, and Energy Biotechnology.

Selected peer-reviewed articles：
Microbial Surfactants & Bio-based Surfactants:
(1)Gang H-Z, Liu J-F & Mu B-Z* (2015) Binding structure and kinetics of surfactin monolayer formed at the air/water interface to counterions: a molecular dynamics simulation study. BBA-Biomembranes 1848:1955-1962
(2)Zhang Q-Q, Cai B-X, Xu W-J, Gang H-Z, Yang S-Z & Mu, B-Z* (2015) Rebirth of waste cooking oil to novel bio-based surfactants. Scientific Reports 5, 9971
(3)Zhang Q-Q, Cai B-X, Gang H-Z, Yang S-Z & Mu B-Z* (2014) A family of novel bio-based zwitterionic surfactants derived from oleic acid. RSC Adv 4: 38393-38396
(4)She A-Q, Gang H-Z & Mu B-Z* (2012) Temperature influence on the structure and interfacial properties of surfactin micelle: a molecular dynamics simulation study. J Phys Chem B 116: 12735-12743
(5)Gang H-Z, Liu J-F & Mu B-Z* (2011) Molecular dynamics study of surfactin monolayer at the air/water interface. J Phys Chem B 115: 12770-12777
(6)Gang H-Z, Liu J-F & Mu B-Z* (2010) Interfacial behavior of surfactin at the decane/water interface: a molecular dynamics simulation. J Phys Chem B 114: 14947-14954
(7)Gang H-Z, Liu J-F & Mu B-Z* (2010) Molecular dynamics simulation of surfactin derivatives at the decane / water interface at low surface coverage. J Phys Chem B 114: 2728-2737
(8)Li Y, Zou A-H, Ye R-Q & Mu B-Z* (2009) Counterion-induced changes to the micellization of surfactin-C16 aqueous solution. J Phys Chem B 113: 15272 -15277
(9)Yang S-Z, Wei D-Z & Mu B-Z * (2007) Determination of the structure of the fatty acid chain in a cyclic lipopeptide using GC-MS. J Biochem Biophys Meth 70: 519-523
(10)Yang S-Z, Wei D-Z & Mu B-Z* (2006) Determination of the amino acid sequence in a cyclic lipopeptide using MS with DHT mechanism. J Biochem Biophys Meth 68: 69-74

Bio-degradation of Hydrocarbons & Bio-transformation of CO2 in Petroleum Reservoirs:
(11)Li C-Y, Zhang D, Li X-X, Mbadinga SM, Yang S-Z, Liu J-F, Gu J-D & Mu B-Z* (2016) The biofilm property and its correlationship with high-molecular-weight polyacrylamide degradation in a water injection pipeline of Daqing oilfield. Journal of Hazardous Materials 304: 388–399
(12)Liang B, Wang L-Y, Zhou Z-C, Mbadinga SM, Zhou L, Liu J-F, Yang S-Z, Gu J-D & Mu B-Z* (2016) High frequency of Thermodesulfovibrio spp. and Anaerolineaceae in association with Methanoculleus spp. in a long-term incubation of n-alkanes-degrading methanogenic enrichment culture. Front Microbiol 7, 1431
(13)Yang G-C, Zhou L, Mbadinga SM, Liu J-F, Yang S-Z, Gu J-D, Mu B-Z* (2016) Formate-dependent microbial conversion of CO2 and the dominant pathways of Methanogenesis in production water of high-temperature oil reservoirs amended with bicarbonate. Front Microbiol 7, 365
(14)Yang G-C, Zhou L, Mbadinga SM, You J, Yang H-Z, Liu J-F, Yang S-Z, Gu J-D & Mu B.Z* (2016) Activation of CO2- reducing methanogens in oil reservoir after addition of nutrient. J Biosci Bioeng 22: 740-747
(15)Bian X-Y, Mbadinga SM, Liu Y-F, Yang S-Z, Liu J-F, Ye R-Q, Gu J-D* & Mu B-Z* (2015) Insights into the anaerobic biodegradation pathway of n-alkanes in oil reservoirs by detection of signature metabolites. Scientific Reports 5, 9801
(16)Liang B, Wang L-Y, Mbadinga SM, Liu J-F, Yang S-Z, Gu J-D & Mu B-Z* (2015) Anaerolineaceae and methanosaeta turned to be turned dominant microorganisms in methanogenic alkanes-degrading enrichment culture afterafter 1300 days. Appl Microbiol Biotechnol Exp. 5, 37
(17)Mbadinga S M, Li K-P, Zhou L, Wang L-Y, Yang S-Z, Liu J-F, Gu J-D & Mu B-Z. (2012) Analysis of alkane-dependent methanogenic community derived from production water of high temperature petroleum reservoir. Appl Microbiol Biotechnol 96:531-42
(18)Wang L-Y, Li W, Mbadinga SM, Liu J-F, Gu J-D & Mu B-Z* (2012) Microbial community shift correlated with the carbon available enriched from an oily sludge over 500 days of methanogenic incubation. Geomicrobiol J 29:716-726
(19)Zhou L, Li K-P, Mbadinga SM, Yang S-Z, Gu J-D & Mu B-Z* (2012) Analyses of n-alkanes degrading community dynamics of a high-temperature methanogenic consortium enriched from production water of a petroleum reservoir by a combination of molecular techniques. Ecotoxicology 21:1680-1691
(20)Mbadinga SM, Wang L-Y, Zhou L, Liu J-F, Gu J-D & Mu B-Z* (2011) Microbial community in Methanogenic enrichment of production water from oil reservoirs. IBB 65: 1-13

Molecular Microbial Communities in Petroleum Reservoirs & Enhanced Energy Recovery:
(21)You J, Wu G, Ren F-P, Qi C, Yu B, Xue Y-F & Mu B-Z* (2016) Microbial community dynamics in Baolige oilfield during MEOR treatment revealed by Illumina MiSeq sequencing. Appl Microbiol Biotechnol 100: 1469 -1478
(22)Liu J-F, Sun X-B, Mbadinga SM, Yang G-C, Gu J-D* & Mu B-Z* (2015) Microbial communities in water samples from oil fields previously subjected to CO2-flooding and thoroughly water-flooding using functional genes as molecular markers with respect to microbial fixation of sequestered CO2. Front Microbiol 6: 236.
(23)Wang L-Y, Sun X-B, Liu J-F, Gu J-D & Mu B-Z* (2014) Comparison of bacterial community in aqueous and oil phases of the water-flooded petroleum reservoir using Pyrosequencing and clone library approaches. Appl Microbiol Biotechnol 98:4209-4221
(24)Guan J, Zhang B-L, Mbadinga SM, Liu J-F, Gu J-D & Mu B-Z* (2014) Functional genes (dsr) approach reveals similar sulphidogenic prokaryotes diversity but different structure in saline waters from corroding high temperature petroleum reservoirs. Appl Microbiol Biotechnol 98: 1871-1882
(25)Wang L-Y, Duan R-Y, Liu J-F, Yang S-Z, Gu J-D & Mu B-Z* (2012) Molecular analysis of the microbial community structures in water-flooding petroleum reservoirs with different temperatures. Biogeosciences 9: 4645-4659
(26)Guan J, Xia L-P, Wang L-Y, Liu J-F, Gu J-D & Mu B-Z* (2013) Diversity and distribution of sulfate- reducing bacterial communities in four different petroleum reservoirs using 16S rRNA gene from nested PCR and dsrAB gene. IBB 76:58-66
(27)Feng W-W, Liu J-F, Gu J-D & Mu B-Z* (2011) Nitrate-reducing community in production water of three oil reservoirs and their responses to different carbon sources revealed by nitrate-reductase Gene (napA). IBB 65:1081- 1086
(28)Gang H-Z, Liu M-T & Mu B-Z* (2005) Modeling of microorganism transport in a cylindrical pore. J Ind Microbiol Biotechnol 35: 495-500
(29)Li H, Yang S-Z, Mu B-Z*, et al. (2007) Molecular phylogenetic diversity of the microbial community associated with a high-temperature petroleum reservoir at an offshore oilfield. FEMS Microbiol Ecol 60: 74-84
(30)Li H, Yang S-Z, Mu B-Z*, et al. (2006) Molecular analysis of bacterial community structure in a continental high-temperature and water-flooded petroleum reservoir. FEMS Microbiol Lett 257: 92-98

Presentations：
(1)Mu B-Z, Mbadinga S M, Gu J-D. Microbial communities in subsurface petroleum reservoirs and their potentials in microbial enhanced energy recovery. 10th International Congress on Chemical Engineering and Biotechnology, 9-12 May, 2016, Beijing (Invited)
(2)Mu B-Z, Mbadinga S M, Gu J-D. Role of microbial community in subsurface petroleum reservoirs. Sino German Workshop on Microbial Enhanced Oil Recovery, 20-24 April, 2015 Leipzig, Germany (Invited)
(3)Mu B-Z, Zhang Q-Q, Gu J-D, Sand W. Bio-based surfactant for enhanced oil recovery and oil spill treatment, ACHEMA 2015 Congress, 15-19 June, 2015, Frankfurt, Germany (Invited)
(4)Mu B-Z, Zhang Q-Q. Biobased Surfactants. ECF2015 5th Asia Shale Gas Summit,12-14 Oct. 2015, Shanghai (Invited)
(5)Mu B-Z, Mbadinga S M, Wang Y-L, Zhou L, Gu J-D, Suflita,J. Role of microbial community in subsurface petroleum reservoirs: the potential application in microbial enhanced energy recovery. China-US Joint Annual Symposium, Water, Energy, and Ecosystem Sustainable Development, 26-28 Oct, 2014, Hefei (keynote)
(6)Mu B-Z, Bian X-Y, Mbadinga S M, Gu J-D. Detection of signature biomarkers implicated in anaerobic degradation of hydrocarbons in petroleum reservoirs via Mass spectral characteristics of chemically synthesized alkylsuccinates. International Symposium on Applied Microbiology and Molecular Biology in Oil Systems (ISMOS-4), 25-28 Aug, 2013, Rio, Brazil (Invited)
(7)Mu B-Z, Bian X-Y, Mbadinga S M, Gu J-D. Identification of alkylsuccinate synthase genes and characterization of microbial community structure in distinct petroleum reservoirs fluids of China, International Symposium on Applied Microbiology and Molecular Biology in Oil Systems (ISMOS-3), 13-15 June, 2011, Calgary (Invited)
(8)Mu B-Z, Wang Y-L, Mbadinga SM, Zhou L, Liu J-F, Gu J-D. Molecular microbial community in water-flooding petroleum reservoirs with different temperatures. The First International Conference on Geomicrobial Ecotoxicology, 28-31 May, 2011, Wuhan (Keynote)
(9)Mu B-Z, Wang Y-L,Mbadinga S M, Zhou L, Liu J-F, Gu J-D. Phylogenetic diversity of the Archaeal community in petroleum reservoirs with different temperatures. Inaugural Meeting of BERGEY’s International Society for Microbial Systematics, 19-23 May, 2011, Beijing (Invited)
(10)Mu B-Z, Wang Y-L, Liu J-F, Yang S-Z. Molecular characterization of the Archaeal community in water-flooding petroleum reservoirs. Asian Congress on Biotechnology (ACB-2011), 11-15 May, 2011, Shanghai (Invited)