潘逸萱 研究
生命科学学院??????


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个人资料
研究方向
开授课程
科研项目
学术成果
荣誉及奖励







个人资料
部门： 生命科学学院
毕业院校： 台湾阳明大学
学位： 博士
学历： 博士
邮编： 200062
联系电话： +3
传真： 无
电子邮箱： yihsuanp@gmail.com
办公地址： 华东师范大学中山北路校区理科大楼B栋326-328室
通讯地址： 200062 中山北路3663号理科大楼B栋327室333室

教育经历
2009.03 -2011.03 华东师范大学，分子与生态学研究组(博士后)
2002.09-2005.03 阳明大学，生化暨分子生物学，博士（理学博士）
2000.09-2002.06 阳明大学，生化暨分子生物学，硕士（理学硕士）
1996.09-2000.06 海洋大学，水产养殖与分子生物学，学士（农学学位）


工作经历
2011– 2017 华东师范大学—生命科学学院
分子生态与进化研究室
2017– 迄今华东师范大学—生命科学学院
脑功能基因组学教育部重点实验室/上海市脑功能基因组学重点实验室


个人简介

社会兼职
台湾海洋大学（沪）华东校友会 副会长
阳明大学大陆校友会 财务


研究方向
我以多组学分析、分子生物学与生物化学方法研究精神益生菌对哺乳动物脑功能产生的影响，探讨哺乳类动物脑功能疾病的发病机制；同时以冬眠哺乳类动物作为模型探讨极端代谢调控（氨基酸代谢和血糖调节）与适应性进化，并参与ADAMTS-18的生理功能探索。
研究主要方向：分子神经生物学；神经系统疾病
Websites:https://www.researchgate.net/profile/Yi-Hsuan_Pan;http://orcid.org/0000-0001-5156-9887

Research projects:
1. Psycobiotics,Brain function and diseases: Autism, PD & Prion infectious diseases.
2. Molecular ecology and evolution
3. Regulation of blood glucose level in type 2 diabetes (FDA IND 145464).
4. Physiological functions of ADAMTS-18
5.GenBrowser for monitoring transmission and evolution of SARS-CoV-2
(https://www.biosino.org/genbrowser;https://bigd.big.ac.cn/genbrowser)








审稿期刊：
Antioxidants & Redox Signaling,Cryobiology, Frontiers in Microbiology,Journal of Proteomics


开授课程

当代生态学 （研究生，专业选修）
生物化学与分子生物学 （研究生，基础必修）
专业英语，英文科技写作 （研究生，专业必修，专业选修）
现代生物学进展 —— 组学研究剖析 （研究生，专业必修）
冬眠研究进展与医学应用探讨（研究生，专业选修）
营养学（上海市全英文示范教学课程，本科生，通识选修 —— 2020）


科研项目


学术成果

Wenjie Huang¹, Chen-Chung Liao¹, Yijie Han, Junyan Lv, Ming Lei, Yangyang Li, Qingyun Lv, Dong Dong, Shuyi Zhang, Yi-Husan Pan*, Jian Luo* (2020) Co-activation of Akt, Nrf2, and NF-κB signals under UPR_ERin torpid Myotis rickettibats for survival. Communications biology.doi.org/10.1038/s42003-020-01378-2
Tiantian Lu, Xiaotian Lin,Yi-Hsuan Pan, NingYang, ShuaiYe, Qi Zhang, Caiyun Wang, Rui Zhu, Tianhao Zhang, Thomas M. Wisniewski, Zhongwei Cao, Bi-Sen Ding, Suying Dang, WeiZhang* (2020) ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.iScience.doi.org/10.1016/j.isci.2020.101472.
Chenhua Pan, Junwei Yang, Xiangyi Zhang, Ying Chen, Shunxiong Wei, Guohua Yu,Yi-Hsuan Pan, Jiyan Ma*, Chonggang Yuan* (2020) Oral ingestion of synthetically generated recombinant prion is sufficient to cause prion disease in wild-type mice.Pathogens9 (8), 653. doi.org/10.3390/pathogens**.
H Sun, J Wang, Y Xing,YH Pan, X Mao* (2020) Gut transcriptomic changes during hibernation in the greater horseshoe bat (Rhinolophus ferrumequinum).Frontiers in Zoology17, Articlenumber:21. doi.org/10.1186/s12983-020-00366-w.
Yuting Wang¹, Guangyi Dai¹, Zhili Gu¹, Guopeng Liu¹, Ke Tang,Yi-Hsuan Pan, Yujie Chen, Xin Lin, Nan Wu, Haoshan Chen, Su Feng, Shou Qiu, Hongduo Sun, Qian Li, Chuan Xu, Yanan Mao, Yong Edward Zhang, Philipp Khaitovich, Yan-Ling Wang, Qunxiu Liu, Jing-Dong Jackie Han, Zhen Shao, Gang Wei, Chun Xu, Naihe Jing and Haipeng Li* (2020) Accelerated evolution of anLhx2enhancer shapes mammalian social hierarchies.Cell Research. 0:1–13. doi.org/10.1038/s41422-020-0308-7.
Tiantian Lu, Tianhao Zhang, Caiyun Wang, Ning Yang,Yi-Hsuan Pan, Suying Dang, Wei Zhang* (2020)Adamts18deficiency in zebrafish embryo causes defective trunk angiogenesis and caudal vein plexus formation.Biochemical and Biophysical Research Communications. doi.org/10.1016/j.bbrc.2019.10.202
Yi-Hsuan Pan, Wu Nan, Xiao-Bing Yuan* (2019) Toward a better understanding of neuronal migration deficits in autism spectrum disorders.Front. Cell Dev. Biol.doi:10.3389/fcell.2019.00205
Chunlei Wang,Yi-Hsuan Pan, Yue Wang, Gene Blatt and Xiao-Bing Yuan* (2019) Segregated expressions of autism risk genesCdh11andCdh9in autism-relevant regions of developing cerebellum.Molecular Brain. doi.org/10.1186/s13041-019-0461-4
Rui Zhu,Yi-Hsuan Pan, Lijie Sun, Tianhao Zhang, Caiyun Wang, Shuai Ye, Ning Yang, Tiantian Lu, Thomas Wisniewski, Suying Dang, Wei Zhang* (2019) ADAMTS18 deficiency affects neuronal morphogenesis and reduces the levels of depression-like behaviors in mice.Neuroscience. doi.org/10.1016/j.neuroscience.2018.12.025
Rui Zhu,Yi-Hsuan Pan, Tiantian Lu, Suying Dang, Chen-Chung Liao and Wei Zhang* (2018) Vascular Proteomics Reveals Critical Roles of ADAMTS18 in Stroke Associated with Imbalanced Level of Von Willebrand Factor Versus ADAMTS13.Blood. doi.org/10.1182/blood-2018-99-110341
Huiling Xue, Zhe Wang, Yongjie Hua, Shanshan Ke, Yao Wang, Junpeng Zhang,Yi-Hsuan Pan, Wenjie Huang, David M. Irwin, Shuyi Zhang* (2018) Molecular signatures and functional analysis of beige adipocytes induced fromin vivointra-abdominal adipocytes.Science Advances. doi: 10.1126/sciadv.aar5319
Di Liu, Shenghui Zheng, Guantao Zheng, Qingyun Lv, Bin Shen, Xinpu Yuan,Yi-Hsuan Pan* (2018) Adaptation of the FK506 Binding Protein 1B to Hibernation in Bats.Cryobiology. doi.org/10.1016/j.cryobiol.2018.07.004
Rui Zhu, Mengting Cheng, Tiantian Lu, Ning Yang, Shuai Ye,Yi-Hsuan Pan, Tao Hong, Suying Dang, Wei Zhang* (2017) A Disintegrin and Metalloproteinase with Thrombospondin Motifs 18 Deficiency Leads to Visceral Adiposity and Associated Metabolic Syndrome in Mice.The American Journal of pathology. doi.org/10.1016/j.ajpath.2017.10.020
Qiuyuan Yin, Yijian Zhang, Dong Dong, Ming Lei, Shuyi Zhang, Chen-Chung Liao*,Yi-Hsuan Pan*(2017) Maintenance of neural activities in torpidRhinolophus ferrumequinumbats revealed by 2D gel-based proteome analysis.Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. doi.org/10.1016/jbbapap.2017.04.006
Dong Dong, Ming Lei, Panyu Hua,Yi-Hsuan Pan, Shuo Mu, Guantao Zheng, Erli Pang, Kui Lin, and Shuyi Zhang* (2016) The Genomes of Two Bat Species with Long Constant Frequency Echolocation Calls.Mol Biol Evoldoi: 10.1093/molbev/msw231
Qiuyuan Yin, Hanxiao Ge, Chen-Chong Liao, Di Liu, Shuyi Zhang*, andYi-Hsuan Pan*(2016) Antioxidant Defenses in the Brains of Bats during Hibernation.PLoS ONE(3): e**. doi: 10.1371/journal.pone. **
Qiuyuan Yin, Lei Zhu, Di Liu, David M. Irwin, Shuyi Zhang*, andYi-Hsuan Pan*(2016) Molecular Evolution of the Nuclear Factor (Erythroid-Derived 2)-Like 2 Gene Nrf2 in Old World Fruit Bats (Chiroptera: Pteropodidae).PLoS ONE11(1): e**. doi:10.1371/journal. pone.**
Yijie Han, Guantao Zheng, Tianxiao Yang, Shuyi Zhang, Dong Dong, andYi-Hsuan Pan*(2015) Adaptation of Peroxisome Proliferator-activated Receptor alpha to Hibernation in Bats.BMC Evolutionary Biology.doi:10.1186/s12862-015-0373-6
Yih-Huei Uena, Chen-Chung Liao, Jung-ChunLin,Yi-Hsuan Pan, Yi-Chung Liu,You-Chia Chen, Wei-Jung Chen, Chih-Chun Tai, Kuan-Wei Lee, Yun-Ru Liu, Hung-TseLine, Ching-Yu Lin (2015) Analysis of differentially expressed novel post-translational modifications of plasma apolipoprotein E in Taiwanese females with breast cancer.Journal of Proteomics.126: 252 262. doi.org/10.1016/j.jprot.2015.05.038
Ming Lei, Dong Dong*, Shuo Mu,Yi-Hsuan Pan,and Shuyi Zhang* (2014) Comparison of brain transcriptomes between active and torpid episodes of the greater horseshoe bats (Rhinolophus ferrumequinum).PLoS ONE. doi: 10.1371/journal.pone.**.
Yijian Zhang¹,Yi-Hsuan Pan¹, Qiuyuan Yin, Tianxiao Yang, Dong Dong, Chen-Chung Liao* and Shuyi Zhang* (2014) Critical Roles of Mitochondria in Brain Activities of TorpidMyotis rickettiBats Revealed by a Proteomic Approach.Journal of Proteomics.105 (13): 266-284.
Yijian Zhang, Tengteng Zhu, Lina Wang,Yi-Hsuan Pan*and Shuyi Zhang* (2013) Homocysteine Homeostasis and Betaine-Homocysteinem S-methyltransferase Expression in the Brian of Hibernating Bats.PLoS ONE. doi: 10.1371/journal.pone.**.
Yi-Hsuan Pan, Yijian Zhang, Jie Cui, Yang Liu, Bronwyn M. McAllan, Chen-Chung Liao*, Shuyi Zhang* (2013) Adaptation of Phenylalanine and Tyrosine Catabolic Pathway to Hibernation in Bats.PLoS ONE. doi.org/10.1371/journal.pone.**.
Lingjiang He¹?Yihsuan Pan¹? Guimei He? Benfu Lin? Chen-Chung Liao? Xueguo Zuo? Lihong Yuan* (2010) Structural and functional studies of leptins from hibernating and non-hibernating bats.General and Comparative Endocrinology? 168.
Jie Cui¹?Yi-Hsuan Pan¹? Yijian Zhang? Gareth Jones? Shuyi Zhang* (2011) Progressive Pseudogenization: Vitamin C Synthesis and Its Loss in Bats.Mol. Biol. Evol. 28 (2):1025–103
李昭鋐，应用分子生物学（ISBN 978-957-616-918-2, 2007），艺轩图书出版社。
Pan Y-H.? Liao C-C.? Duan K-J? Liang P-H? Yuan H-S.? Hu S-T? Chak K-F* (2006) The critical roles of polyamines in regulating ColE7 production and restricting ColE7 uptake of the colicin producingEscherichia coli.Journal of Biological Chemistry. 281(19):13083-13091.
阳明大学博士班优良论文奖学金（2005）。
International Conference on polyamines Best Poster and Presentation Award (2004) awarded by Prof. Kazuei Igarashi et al.
阳明大学硕士班优良学术论文奖学金（2001）。
海洋大学水产养殖系书卷奖（1999）。




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