黄青清
副研究员
科学与技术跨学科高等研究院
联系电话：021-62238771

办公时间：
传真：021-62602475

主页网址：
办公地点：理科大楼B430室

电子邮箱：qqhuang@sat.ecnu.edu.cn
通讯地址：上海市中山北路3663号理科大楼B430室


研究方向
药物化学‚主要从事抗病毒类、抗肿瘤药物的研究和新药研发合成工艺的研究。
http://wlu.faculty.ecnu.cn

社会兼职
学术成果
近期发表论文：
1.Huang‚Q.;He‚R.;Kozikowski‚A.P.Stereochemistryattheforefrontinthedesignanddiscoveryofnovelanti-tuberculosisagents.Curr.Top.Med.Chem.2011‚11(7)‚810–818.
2.Guo‚S.;Song‚Y.;Huang‚Q.;Yuan‚H.;Wan‚B.;Wang‚Y.;He‚R.;Beconi‚M.G.‚Franzblau‚S.G.;Kozikowski‚A.P.Identification‚synthesis‚andpharmacologicalevaluationoftetrahydroindazolebasedligandsasnovelantituberculosisagents.J.Med.Chem.2010‚53(2)‚649–659.
3.Mao‚J.;Yuan‚H.;Wang‚Y.;Wan‚B.;Pieroni‚M.;Huang‚Q.;vanBreemen‚R.B.;Kozikowski‚A.P.;Franzblau‚S.G.Fromserendipitytorationalantituberculosisdrugdiscoveryofmefloquine-isoxazolecarboxylicacidesters.J.Med.Chem.2009‚52(22)‚6966–6978.
4.Huang‚Q.;Mao‚J.;Wan‚B.;Wang‚Y.;Brun‚R.;Franzblau‚S.G.;Kozikowski‚A.P.Searchingfornewcuresfortuberculosis:design‚synthesis‚andbiologicalevaluationof2-methylbenzothiazoles.J.Med.Chem.2009‚52(21)‚6757–6767.
5.Huang‚Q.-Q.;Chen‚L.-H.;Nan‚F.-J.RCM-mediatedstereoselectivesynthesisofthreenoveltetrahydroisoquinolinetetracycliccoreframeworks.TetrahedronLett.2008‚49(35)‚5141–5143.
6.Ma‚Z.-Q.;Xie‚S.-X.;Huang‚Q.-Q.;Nan‚F.-J.;Hurley‚T.D.;Ye‚Q.-Z.StructuralanalysisofinhibitionofE.colimethionineaminopeptidase:implicationofloopflexibilityinselectiveinhibitionofbacterialenzymes.BMCStructuralBiology2007‚7‚84.
7.Huang‚M.;Xie‚S.-X.;Ma‚Z.-Q.;Huang‚Q.-Q.;Nan‚F.-J.;Ye‚Q.-Z.Inhibitionofmonometalatedmethionineaminopeptidase:inhibitordiscoveryandcrystallographicanalysis.J.Med.Chem.2007‚50(23)‚5735–5742.
8.Huang‚Q.-Q.;Huang‚M.;Nan‚F.-J.;Ye‚Q.-Z.Metalloform-selectiveinhibition:synthesisandstructure-activityanalysisofMn(II)-form-selectiveinhibitorsofEscherichiacolimethionineaminopeptidase.Bioorg.Med.Chem.Lett.2005‚15‚5386–5391.
9.Cui‚Y.-M.;Huang‚Q.-Q.;Xu‚J.;Chen‚L.-L.;Li‚J.-Y.;Ye‚Q.-Z.;Li‚J.;Nan‚F.-J.IdentificationofpotenttypeIMetAPsinhibitorsbysimplebioisostericreplacement.Part1:synthesisandpreliminarySARstudiesofthiazole-4-carboxylicacidthiazol-2-ylamide(TCAT)derivatives.Bioorg.Med.Chem.Lett.2005‚15‚3732–3736.
10.Cui‚Y.-M.;Huang‚Q.-Q.;Xu‚J.;Chen‚L.-L.;Li‚J.-Y.;Ye‚Q.-Z.;Li‚J.;Nan‚F.-J.IdentificationofpotenttypeIMetAPsinhibitorsbysimplebioisostericreplacement.Part2:SARstudiesof5-heteroalkylsubstitutedTCATderivatives.Bioorg.Med.Chem.Lett.2005‚15‚4130–4135.