高栓虎
“英才计划”特聘研究员博士生导师
化学系

上海绿色化学与化工工程绿色化重点实验室

联系电话：021-62604784

办公时间：周一至周六
传真：021-62604784

主页网址：
办公地点：化学馆C-303室

电子邮箱：shgao@chem.ecnu.edu.cn
通讯地址：上海市中山北路3663号200062华东师范大学化学馆C-303室


研究方向
研究方向：

主要研究方向为活性天然产物全合成及其化学生物学与药物化学研究。将针对若干结构新颖、活性独特、合成上具有挑战性的天然产物‚开展一系列全合成及相关方法学研究。研究所涉及的课题均以目标导向的天然产物全合成(TOS)为核心‚将通过多样性合成（DOS）及功能导向性合成（FOS）一系列功能分子类似物‚进而以合作的形式开展其化学生物学及药物化学研究‚以探究其潜在的医药价值。

有机反应与合成：
OrganicReactionsandSynthesis
Lecture1–OrganicReactionsandSynthesis[Introduction]
Lecture2–RedoxinOrganicSynthesisA[Oxidation]
Lecture3–RedoxinOrganicSynthesisB[Reduction]
Lecture4–ProtectingGroupsinOrganicSynthesis
Lecture5–TheCarbon-CarbonmultipleBond
Lecture6–TransitionMetalCatalyzedReactionsinOrganicSynthesisA[Ru]
Lecture7–TransitionMetalCatalyzedReactionsinOrganicSynthesisB[Pd]
Lecture8–RadicalReactionsinOrganicSynthesis
Lecture9–CarbeneinOrganicSynthesis
Lecture10–CycloadditionsinOrganicSynthesisA[2+2,2+3]
Lecture11–CycloadditionsinOrganicSynthesisB[2+4]
Lecture12–ElectrocyclicReactionsinOrganicSynthesis
Lecture13–RearrangementReactionsinOrganicSynthesis
Lecture14–ConstructionofQuaternaryCenter
Lecture15–CascadeReactionsinOrganicSynthesis
Lecture16–NaturalProductSynthesis(CaseStudy--Strychnine)
Lecture17–NaturalProductSynthesis(CaseStudy--Cortistatin)
Lecture18–NaturalProductSynthesis(CaseStudy—Nakiterpiosin)

社会兼职
学术成果
1.Jun,Yin;Kong,Lili;GaoShuanhu*SyntheticProgressofFusarisetinAChin.J.Org.Chem.2013,33,259-266.
2.JunYin‚ChengWang‚LiliKong‚ShujunCai‚ShuanhuGao*AsymmetricSynthesisandBiosyntheticImplicationsof(+)-FusarisetinAAngew.Chem.Int.Ed.2012‚51,7786-7789.(HighlightedinChemical&EngineeringNews)

3.Gao,Shuanhu;Wang,Qiaoling;Wang,Gelin;Lomenick,Brett;Liu,Jie;Fan,Chih-Wei;Deng,Lih-Wen;Huang,Jing;Lum,Lawrence;Chen,ChuoTheChemistryandBiologyofNakiterpiosin-C-nor-D-HomosteroidsSynlett,2012,23,2298.
4.ShuanhuGao;QiaolingWang;LawrenceLum;ChuoChen*.ChemicalandBiologicalStudiesofNakiterpiosinandNakiterpiosinoneJ.Am.Chem.Soc.2010‚132‚371.

5.ShuanhuGao;QiaolingWang;ChuoChen*.SynthesisandStructureRevisionofNakiterpiosinJ.Am.Chem.Soc.2009‚131‚1410.
6.J.R.Falck;*ShuanhuGao;RaviNagaPrasad;SreenivasuluReddyKoduru.Electrophilicα-thiocyanationofchiralandachiralN-acylimides.Aconvenientrouteto5-substitutedand5‚5-disubstituted2‚4-thiazolidinedionesBioorg.Med.Chem.Lett.2008‚18‚1768.

7.ShuanhuGao;Yong-QiangTu*;XiangdongHu;RongbaoHua;YijunJiang;YumingZhao;XiaohuiFan;ShuyuZhang.GeneralandEfficientStrategyforErythrinanandHomoerythrinanAlkaloids:Synthesesof(±)-3-demethoxyerythratidinoneand(±)-ErysotramidineOrg.Lett.2006‚8‚2373.

8.ShuanhuGao;Yong-QiangTu*;ZhenleiSong;AixiaWang;XiaohuiFan;YijunJiang.AGeneralandEfficientStrategyfor7-Aryloctahydroindoleandcis-3a-AryloctahydroindoleAlkaloids:TotalSynthesesof(±)-γ-Lycoraneand(±)-CrinaneJ.Org.Chem.2005‚70‚6523.
9.ShuanhuGao;Yanxing,Jia;XuezhiZhao;YongqiangTu.ANovelStrategyfortheKeyFullySubstitutedCyclopentenedioneMoietyofMadindonlinesviaAlEt3-promotedTandemReductiveRearrangementofHydroxyEpoxidesChin.J.Chem.2006,24,595.
10.Xiang-DongHu;Yong-QiangTu*;EnZhang;ShuanhuGao;ShaohuaWang;AixiaWang;Chun-AnFan;MinWang.TotalSynthesisof(±)-GalanthamineOrg.Lett.2006‚8‚1823.
小组成员及照片