胡连瑞
性别：男
学院：理学院
职称：讲师
学位：研究生
学历：博士
毕业院校：中国科学院化学研究所
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电子邮箱：hulianrui@iccas.ac.cn
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个人简介
胡连瑞，博士，讲师，男，西华大学青年****后备人才。2010年获西华大学应用化学专业本科学位，2011-2012年分别就职于康龙化成（北京）新药技术有限公司、上海睿智化学研究有限公司，任助理研究员。2017年获中国科学院化学研究所物理化学专业博士学位，2017年毕业任职于西华大学理学院，2019年赴德国哥廷根大学开展博士后研究。主要从事理论与计算化学等方面的科研工作。围绕高精度从头算波函数方法，3d过渡金属催化有机反应机理研究，生物酶反应机理等方面的研究已发表相关论文17篇，其中JCR一区论文7篇，包括J. Am. Chem. Soc.(5篇)，Acs Catal.(1篇), J. Chem. Theory Comput.(3篇)，J. Phys. Chem. Lett.(1篇), Chem. Eur. J.(2篇)等SCI收录论文。先后受邀参加多次国际国内学术研讨会，作为项目负责人承担国家教育部、四川省科技厅面上项目等多个纵向项目的研究工作。




工作经历
2010~2011 康龙化成(北京)新药技术有限公司 助理研究员2011~2012 上海睿智化学研究有限公司 助理研究员




教育经历
2012.09~2017.07 中国科学院化学研究所 物理化学专业(硕博连读) 博士2006.09~2010.06 西华大学 应用化学专业 学士




研究方向
1.过渡金属催化的有机反应机理(主要是3d过渡金属)
2.高精度理论计算研究
3.分子结构和分子光谱的理论模拟
4.生物酶反应机理





学术成果
1.Hu, L. R.;Chen, H.* Substrate-Dependent Two-State Reactivity in Iron-Catalyzed Alkene [2+2] Cycloaddition ReactionsJ. Am. Chem. Soc.2017, 139, 15564-15567.
2.Hu, L. R.;Chen, H.* What Factors Control the Reactivity of Cobalt-Imido Complexes in C-H Bond Activation via Hydrogen Abstraction?Acs Catal.2017,7, 285.
3.Hu, L. R.;Chen, K.; Chen, H.* Modeling σ-Bond Activations by Nickel(0) Beyond Common Approximations: How Accurately Can We Describe Closed-Shell Oxidative Addition Reactions Mediated by Low-Valent Late 3d Transition Metal?J. Chem. Theory Comput.2017,13, 4841-4853.(L.H. and K.C. contributed equally.)
4.Hu, L. R.;Chen, H.* Assessment of DFT Methods for Computing Activation Energies of W/Mo-Mediated ReactionsJ. Chem. Theory Comput.2015,11, 4601.
5.Hu, L. R.;Chen, H.* Comparative thereotical study on C-C/C-N/C-Br Bond Formations in RhIII-catalyzed C-H bond functionalizations: stepwise versus concerted mechanismsJ. Organomet. Chem.2018,864, 105-109.
6.Wang, L.;Hu, L. R.;Zhang, H. Z.; Chen, H.*; Deng, L.* Three-Coordinate Iron(IV) Bisimido Complexes with Aminocarbene Ligation: Synthesis, Structure and ReactivityJ. Am. Chem. Soc.2015,137, 14196-14207. (L.W. and L.H. contributed equally.)
7.Liu, J.;Hu, L. R.;Wang, L.; Chen, H.*; Deng, L.* An Iron(II) Ylide Complex as A Masked Open-Shell Iron Alkylidene Species in Its Alkylidene-Transfer Reactions with AlkenesJ. Am. Chem. Soc.2017, 139, 3876-3888. (L.J. and L.H. contributed equally.)
8.Wang, C.; Zhao, C. Y.;Hu, L. R.;Chen, H.*Evidences toward Establishing Mechanism of Cyanobacterial Aldehyde-Deformylating Oxygenase: Asymmetric Aldehyde Activation by Symmetric Diiron CofactorJ. Phys. Chem. Lett.,2016, 7,4427–4432.
9.Kumar, P.; Lee, Y. M.;Hu, L. R.;Chen, J.; Park, Y. J.; Yao, J.; Chen, H.*; Karlin, K. D.*; Nam, W.*Factors That Control the Reactivity of Cobalt(III)-Nitrosyl Complexes in Nitric Oxide Transfer and Dioxygenation Reactions: A Combined Experimental and Theoretical InvestigationJ. Am. Chem. Soc.2016,138, 7753-7762.
10.Lu, S. J.;Hu, L. R.;Xu, X. L.; Xu, H. G.; Chen, H.*; Zheng, W.*Transition from exohedral to endohedral structures of AuGen (n = 2–12) clusters: photoelectron spectroscopy and ab initio calculationsPhys. Chem. Chem. Phys.2016,18, 20321-20329.
11.Sun, Y.; Tang, H.;Chen, K.;Hu, L. R.;Yao, J.; Shaik, S.; Chen, H.* Two-State Reactivity in Low-Valent Iron-Mediated C?H Activation and the Implications for Other First-Row Transition MetalsJ. Am. Chem. Soc.2016,138, 3715-3730.
12.Liu, Q.-Y.;Hu, L. R.; Chen, H.*; He, S.-G.* Photoelectron Imaging Spectroscopy of ZrO?Diatomic AnionChinese J. Chem. Phys.2015,28, 452.
13.Li, Z.-Y.;Hu, L. R.;Liu, Q.-Y.; Ning, C.-G.; Chen, H.*; He, S.-G.*; Yao, J. N. Thermal C?H Bond Activation by MoC3?Cluster Anions: Carbon Stabilizes Low-Spin States for Oxidative AdditionChem. Eur. J.2015,21, 17748-17756.
14.Liu, Q.-Y.;Hu, L. R.;Li, Z.-Y.; Ning, C.-G.; Ma, J.-B.; Chen, H.*; He, S.-G.* Photoelectron Imaging Spectroscopy of MoC?and NbN?Diatomic Anions: A Comparative StudyJ. Chem. Phys.2015,142, 164301.
15.Sun, Y. Y.;Hu, L. R.;Chen, H.* Comparative Assessment of DFT Performances in Ru- and Rh-Promoted σ-Bond ActivationsJ. Chem. Theory Comput.2015,11, 1428.
16.Liu, Y. B.;Hu, L. R.;Chen, H.*; Du, H. F.* An Alkene-Promoted Borane-Catalyzed Highly Stereoselective Hydrogenation of Alkynes to Z- and E-AlkenesChem. Eur. J.2015,21, 3495.
17.Lei, Y.; Wang, L;Hu, L. R.;Shen, X. H.* An approximate approach for the electronic vibration of Al₂O₃X₂(X = H, D, T)Acta. Phys. Sin.2012,61, 232501.





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