王跃锜,2000年毕业于华西医科大学药学专业,2005年获得四川大学生物医学工程博士学位,2005年前往美国East Carolina University从事博士后研究工作,2006年回国后作为博士后加入中国医学科学院肿瘤医院分子肿瘤学国家重点实验室,先后发表文章20余篇,其中包含多篇SCI收录的文章,并作为发明人申请国家发明专利5项,参编专业著作两本,目前专业研究方向为新药开发研究、肿瘤药理学及肿瘤细胞生物学。
发表文章
1. Yueqi Wang, Wenfeng Cao, Zaicheng Yu, Zhihua Liu. Downregulation of a mitochondria associated protein SLP-2 inhibits tumor cell motility, proliferation and enhances cell sensitivity to chemotherapeutic reagents. Cancer Biology & Therapy. Accepted for publication. (SCI; impact factor 2.873)
2. Hua H, Wang Y, Wan C, Liu Y, Zhu B, Wang X, Wang Z, Ding JM. Inhibition of tumorigenesis by intratumoral delivery of the circadian gene mPer2 in C57BL/6 mice. Cancer Gene Ther. 2007; 14(9):815-8. (SCI)
3. Bo Yang, Yangyou Liu, Yuhui Wang, Yueqi Wang, Yanyai Ling, Zhou Jiang, Zhengrong Wang, G.Cornelissen, F.Halberg. Time structure of locomotor activity in mice kept on different light-dark cycles. Biological Rhythm Research. 2007; 38(06):427 – 41. (SCI)
4. Yueqi Wang, Wei Zhou, Yanyou Liu, Chaomin Wan, Yinghui Liu, Tao Peng, Zhengrong Wang, G. Cornelissen, F. Halberg. Ribozyme attenuates reward to morphine in mice by interfering with mper1 gene expression. Biological Rhythm Research. 2006; 37(02):157 – 67. (SCI)
5. Wang X, Wang Y, Xin H, Liu Y, Wang Y, Zheng H, Jiang Z, Wan C, Wang Z, Ding JM. Altered expression of circadian clock gene, mPer1, in mouse brain and kidney under morphine dependence and withdrawal. J Circadian Rhythms. 2006; 4:9. (Pubmed)
6. Hua H, Wang Y, Wan C, Liu Y, Zhu B, Yang C, Wang X, Wang Z, Cornelissen-Guillaume G, Halberg F. Circadian gene mPer2 overexpression induces cancer cell apoptosis. Cancer Sci. 2006; 97(7):589-96. (SCI)
7. Hu L, Lu F, Wang Y, Liu Y, Liu D, Jiang Z, Wan C, Zhu B, Gan L, Wang Y, Wang Z. RACK1, a novel hPER1-interacting protein. J Mol Neurosci. 2006; 29(1):55-63. (SCI)
8.Zhou Jiang, Yanyou Liu, Chaomin Wan, Bo Yang, Li Guo, Yuhui Wang, Yueqi Wang, Wei Zhou, Yinghui Liu, Zhengrong Wang. Different light–dark cycles affect growth rate and food intake of mice. Biological Rhythm Research. 2006; 37(01):11 – 19. (SCI)
9.Y. Liu, Y. Wang, C. Wan, W. Zhou, T. Peng, Y. Liu, Z. Wang, G. Li, G. Cornelisson and F. Halberg. The role of mPer1 in morphine dependence in mice. Neuroscience. 2005; 130(2):383-8. (SCI)
10. WANG Yueqi, HUA hui, ZHU bin, YIN huahu,LIU yanyou, YANG chunlei, WANG Zhengrong. The influence of circadian gene mPeriod2 on Lewis cancer cell. Space Medicine &Medical Engineering. 2005; 18(3):222-3. (EI)
11.Zhou W, Wang Y, Liu Y, Peng W, Xiao J, Zhu B, Wang Z. Deoxyribozymes inhibit the expression of period1 gene in vitro. Sci
12.Peng T, Liu YH, Yang CL, Wan CM, Wang YQ, Wang ZR. A new peptide with membrane-permeable function derived from human circadian proteins. Acta Biochim Biophys Sin (
13.WANG Yueqi, ZHOU Wei, LIU Yanyou, LIU Yinghui, PENG Tao, WANG Zhengrong. Role of Circadian Gene Period1 in Morphine Reward in Mice. Space Medicine &Medical Engineering. 2004; 17(5): 383-5. (EI)
14.LIU Yanyou, YANG Bo, JIANG Zhou, GUO Li, WANG Yueqi, WANG Zhengrong. Effects of Different Light-dark Cycle on Learning and Memory in Mice. Space Medicine &Medical Engineering. 2004; 17(5): 381-2. (EI)
15.LI Yingming , WANG Yuhui , HU Lijuan , LIU Yanyou , WANG Yueqi , WANG Zhengrong. Construction of Yeast Two-hybrid System of the bHLH-PAS Domain of hPer1 cDNA. Space Medicine & Medical Engineering. 2004; 17(6): 461-3. (EI)
16.CHEN Liguo, QU Yi, PENG Wenzhen, WANG Yueqi, XIAO Jing, WANG Zhengrong. Encapsulated ANP cDNA Transfection Cells Attenuate Hypertension in Hypertensive Rats. Space Medicine & Medical Engineering. 2003; 16(1): 77-8. (EI)
17.王跃锜,周薇,刘延友,刘英辉,彭涛,王正荣。反义核酸研究。中国处方药。2003; 2: 19-21。
18.杨芳炬,王正荣,林代平,屈艺,尹华虎,史立丽,郭惠玲,肖静,王跃锜,刘荣韬。参附注射液对心肌缺血犬血流动力学和对动物血压的影响。中国中药杂志。2003; 28(3), 259-62。(核心期刊)
19.杨芳炬,尹华虎,林代平,王跃锜,史立丽,王正荣。参附注射液对动物心律失常的影响。华西药学杂志。2001; 16(5): 345-7。(核心期刊)
王正荣,方治平,王跃锜。肽类和蛋白质类药物口服剂型的研究进展。四川生理科学杂志。2001; 23(2): 63-6。
专利
· 戒毒的反义核酸(ZL**.3)
发明人 王正荣, 王跃锜 ,刘延友,王晓佳
· 心房肽基因转染细胞微囊 (ZL **.6)
发明人 王正荣, 陈立国, 屈艺, 王跃锜
· 一种治疗肿瘤的组合物 (CN**)
发明人 王正荣, 王跃锜
· 异鼠李素及其衍生物在治疗肿瘤药物中的应用 (CN**)
发明人 王正荣, 杨春蕾, 王跃锜, 屈艺
· 钟蛋白穿膜肽药物载体.( CN**)
发明人 王正荣, 彭涛, 杨春蕾, 王跃锜
参编书籍
· 时间生物学 (科学出版社)
· 癌生物学 (译著 科学出版社)
参予会议及报告
· Circadian rhythm of glycogen synthase kinase 3 (GSK 3) in the murine heart. V. Chintalgattu*, S. Vijayakumar, Y. Q. Wang, M. Smith, L. C. Katwa, C. J. Wingard, R. M. Lust, and J. M. Ding. Department of Physiology,
· Role of circadian gene in formation of drug dependence. 国际时间生物学会议,海口,中国, 2004。