个人简介
石三军，博士、****、博士生导师、哈佛医学院留学归国；担任药剂学著名SCI期刊Curr Pharm Design（IF=2.2）客座主编、J Tumor编委、《现代肿瘤医学》青年编委、世中联肿瘤精准医学专委会理事等学术职务；专注于传统脂质材料、新型安全材料在核酸蛋白药物递释上的应用基础研究，其中开发的超分子复合物技术包载核酸药物被多位国际著名****评价为首次报道。主要研究方向(1)核酸药物智能递释系统设计、(2)基于仿生生物材料的新型纳米药物构建、及在中药交叉学科中的应用、(3)肿瘤的多维靶向（3D）治疗；作为负责人主持了国家科技重大专项“重大新药创制”(726万)、国家自然科学基金等项目5项，申请发明专利2项，参编英文专著1部；以第一作者(含共同)或通讯作者身份在Angew Chem Int Edit, Biomaterials, Chemical Engineering Journal, J Control Release等杂志上发表SCI论文17篇，其中IF>10的论文3篇，共被引用1000余次。成果“新型药物制剂关键技术创新与应用”获得四川省科技进步奖1项、重庆市科协自然科学优秀学术论文奖等学术奖项、相关成果多次受邀参加国内外学术会议专题报告；International Journal of Biological Macromolecules“杰出审稿人”。
代表性成果
1.Xili Lu#, Sanjun Shi#, Hanmei Li, Ethan Gerhard, Zhihui Lu, Xinyu Tan, Wenliang Li, Kevin M.Rahn, Denghui Xie, Guodong Xu, Fang Zou, Xiaochun Bai, Jinshan Guo, JianYang. Magnesium oxide-crosslinked low-swelling citrate-based mussel-inspired tissue adhesives. Biomaterials, 2020; 232: 119719. (共同一作，IF=10.317).
2.Lili Wei, Chenyuan Wang, Xianjue Chen, Bing Yang, Kun Shi, Leah R. Benington, Lee Yong Lim, Sanjun Shi*, Jingxin Mo*. Dual-responsive, methotrexate-loaded, ascorbic acid-derived micelles inhibit NF-κB signaling to exert anti-tumor and anti-metastasis effects in an orthotopic mouse model of human choriocarcinoma. Theranostics. 2019; 9(15): 4354-4374. (IF=8.579).
3.Sanjun Shi, Na Kong, Chan Feng, Aram Shajii, Claire Bejgrowicz, Wei Tao*, Omid C. Farokhzad*. Drug Delivery Strategies for the Treatment of Metabolic Diseases. Advanced Healthcare Materials. 2019, **. (IF=7.367).
?该成果受到MaterialsViews新闻报道. https://www.materialsviewschina.com/2019/07/38598
4.Yuanyuan Li#, Sanjun Shi#, Yue Ming, Linli Wang, Chenwen Li, Minghe Luo, Ziwei Li, Bin Li, Jianhong Chen. Specific cancer stem cell-therapy by albumin nanoparticles functionalized with CD44-mediated targeting. Journal of Nanobiotechnology. 2018; 16: 99. (共同一作，IF=6.518).
5.Minghe Luo, Yue Ming, Linli Wang, Yuanyuan Li, Bin Li, Jianhong Chen, Sanjun Shi*. Local delivery of deep marine fungus-derived equisetin from polyvinylpyrrolidone (PVP) nanofibers for anti-MRSA activity. Chemical Engineering Journal. 2018; 350: 157-163. (IF=10.652).
?该成果受到国际权威新闻网“Advanced in Engineering (AIE)”亮点报道. https://advanceseng.com/local-delivery-of-deep-marine-fungus-derived-equisetin-from-pvp-nanofibers-for-anti-mrsa-activity.
6.Sanjun Shi, Likai Yang, Qiu’e Yao, Xin Li, Yue Ming, Yu Zhao. Ascorbic palmitate as a bifunctional drug and nanocarrier of paclitaxel for synergistic anti-tumor therapy. Journal of Biomedical Nanotechnology.2018; 14: 1601-1612. (IF=4.483).
7.Sanjun Shi, Yuanyuan Li, Yue Ming, Chenwen Li, Ziwei Li, Jianhong Chen and Minghe Luo*. Biological activity and chemical composition of the endophytic fungus Fusarium sp. TP-G1 obtained from the root of Dendrobium officinale Kimura et Migo. Records of Natural Products. 2018; 12(6): 549-556. (IF=1.268).
8.Min Zhou, Xin Li, Yuanyuan Li, Qiu’e Yao, Yue Ming, Ziwei Li, Laichun Lu, Sanjun Shi*. Ascorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy. Drug Delivery. 2017; 24: 1230-1242. (IF=4.9).
9.Min Hu, Chenwen Li, Xin Li, Min Zhou, Jianbin Sun, Fangfang Sheng, Sanjun Shi*, Laichun Lu*. Zinc oxide/silver bimetallic nanoencapsulated in PVP/PCL nanofibers for improved antibacterial activity. Artificial Cells, Nanomedicine, and Biotechnology. 2018; 46: 1248-1257. (IF=3.343).
10.Hanmei Li, Tao Liu, Yuxuan Zhu, Qiang Fu, Wanxia Wu, Jie Deng, Li Lan, Sanjun Shi*. An in situ-forming phospholipid-based phase transition gel prolongs the duration of local anesthesia for ropivacaine with minimal toxicity. Acta Biomaterialia 2017; 58, 136-145. (IF=7.242).
11.Yue Ming, Yuanyuan Li, Haiyan Xing, Minghe Luo, Ziwei Li, Jianhong Chen, Jingxin Mo and Sanjun Shi*. Circulating Tumor Cells: from Theory to Nanotechnology-Based Detection. Frontiers in Pharmacology 2017; 8: 35. (IF=4.225).
12.Sanjun Shi*, Min Zhou, Xin Li, et. al. Synergistic active targeting of dually integrin αvβ3/CD44-targeted nanoparticles to B16F10 tumors located at different sitxes of mouse bodies. J Control Release, 2016; 235: 1-13. (IF=7.73).
?该成果受到X-Mol化学综合专业网站的亮点报道(Highlight). https://www.x-mol.com/news/3142.
13.Sanjun Shi, Lu Han, Tao Gong, Zhirong Zhang, Xun Sun. Systemic delivery of microRNA-34a for cancer stem cell therapy. Angew Chem Int Edit, 2013; 52(14): 3901-3905. (IF=12.959).
14.Sanjun Shi, Lu Han, Li Deng, Yanling Zhang, Hongxin Shen, Tao Gong, Zhirong Zhang, Xun Sun. Dual drugs (microRNA-34a and paclitaxel)-loaded functional solid lipid nanoparticles for synergistic cancer cell suppression. J Control Release, 2014; 194(28): 228-237. (IF=7.7).
15.Sanjun Shi, Zhirong Zhong, Jie Liu, Zhirong Zhang, Xun Sun, Tao Gong. Solid lipid nanoparticles loaded with AMOs for suppression of microRNA-21 functions in human lung cancer cells. Pharm Res, 2012; 29(1): 97-109. (IF=3.24).
联系方式：
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