赵凯 研究员 学历：博士研究生
学科：生态学
电话：
邮箱：zhaokai@nwipb.cas.cn
地址：青海省西宁市城西区新宁路23号
邮编：810008




简历介绍
　　赵凯，博士，研究员，博士生导师。西北农业大学动物遗传育种与繁殖专业硕士，西北农林科技大学动物遗传育种与繁殖专业博士，中科院西北高原生物研究所动物学方向博士后。中科院特聘研究员(核心骨干)，中科院“王宽诚率先人才计划”，中国鱼类学会理事，西北高原所“高原生物适应进化机制与分子育种”首席科学家，青海省学科带头人，青海省动物学会副理事长。
　　先后承担国家“十三五”重大研发计划项目、中科院战略性先导科技分子育种专项、中科院知识创新工程重要方向项目、中科院重点部署项目、中科院科技服务STS计划项目、国家自然科学基金项目等。
　　以第一或通讯作者发表SCI论文近40篇，相关论文发表在Molecular Ecology、Molecular Phylogenetics and Evolution、BMC Genomics、BMC Evolutionary Biology、Scientific Reportst等杂志上，其中发表在Molecular Ecology的论文得到杂志主编的点评。


研究方向
高原鱼类表型与功能适应基因组学
高原鱼类分子系统与分子生态学
研究内容：
1）基于基因组水平的比较研究，通过分析高原鱼类在高原极端环境下表型变异与功能适应的相关关键遗传改变，定位和克隆相关的关键基因，并在细胞和模式生物上进行验证，结合生态环境因子等的分析，阐述高原鱼类适应的作用力，揭示生物适应极端环境的分子机制。
2）通过对高原生境下鱼类物种的起源与进化过程、生物与高原环境耦合关系等重大科学问题的研究，阐明高原鱼类的起源模式、种群遗传分化与分布式样、生物适应与进化机制、维持生态系统稳定与可持续发展的关键因素等。


职务


社会任职


获奖及荣誉


代表论文
1．Chenguang Feng, Weiwei Zhou, Yongtao Tang, Yun Gao, Jinmin Chen, Chao Tong, Sijia Liu, Kunyuan Wanghe, Kai Zhao#. Molecular systematics of the Triplophysa robusta (Cobitoidea) complex：Extensive gene flow in a depauperate lineage. Molecular Phylogenetics and Evolution, 2019, 132: 275-283.
2．Fei Tian, Kai Zhao#, Shengbao Xie#. Transcriptomic profiling reveals molecular regulation of seasonal reproduction in Tibetan highland fish, Gymnocypris przewalskii. BMC Genomics, 2019, 20:2.
3．Dehong Tian, Sijia Liu, Guo Yang, Ning Ding, Xue Li, Fei Tian, Kai Zhao#. Genome-Wide Identification and Expression Analysis of the Bone Morphogenetic Protein Family in Hu Sheep. Revista Científica, 2019, 11-20.
4．Yongtao Tang, Chenghong Li, Kunyuan Wanghe. Convergent evolution misled taxonomy in schizothoracine ？shes (Cypriniformes: Cyprinidae). Molecular Phylogenetics and Evolution, 2019,134: 323-337.
5．Sijia Liu, Fei Tian, Cunfang Zhang, Kai Zhao#. Genome-wide identification, phylogeny and expression analysis of G6PC gene family in common carp, Ctprinus carpio. Turkish Journal of Biochemistry, 2019, 44(3).
6．Qi Bao, Chong Li, Chongfeng Xu, Ruiying Zhang, Kai Zhao#, Ziyuan Duan. Procine enterocyte protein Btnl5 negatively regulates NF-kappa B pathway by interfering p65 nuclear translocation. Gene, 2018, 646: 47-55.
7．Cunfang Zhang, Chao Tong, Arne Ludwig, Yongtao Tang, Sijia Liu, Renyi Zhang, Chenguang Feng , Guogang, Zuogang Peng, Kai Zhao#. Adaptive evolution of the Eda gene and scales loss in Schizothoracine fishes in response to uplift of the Tibetan Plateau. International Journal of Molecular Sciences, 2018, 19: 2953.
8．Renyi Zhang, Yongtao Tang, Chenguang Feng, Sijia Liu, Kai Zhao#. Gymnocypris chui Tchang, Yueh & Hwang, 1964 and Gymnocypris scleracanthus Tsao, Wu, Chen & Zhu, 1992 from Lake Langcuo, Qinghai-Tibet Plateau. Journal of Applied Ichthyology, 2017, 33(1): 144-145.
9．Chao Tong, Yongtao Tang, Kai Zhao#. The complete mitochondrial genome of Gymnocypris przewalskii kelukehuensis (Teleostei: Cyprinidae). Conservation Genetics Resources, 2017, 9: 443-445.
10．Chao Tong, Fei Tian, Kai Zhao#. Comprehensive transcriptomic analysis of Tibetan Schizothoracinae fish Gymnocypris przewalskii reveals how it adapts to a high altitude aquatic life. BMC Evolutionary Biology, 2017, 17(1): 74.
11．Chao Tong, Fei Tian, Cunfang Zhang#, Kai Zhao#. The microRNA repertoire of Tibetan naked carp Gymnocypris przewalskii: A case study in Tibetan Schizothoracinae fish. PLoS One, 2017, 12(3): e**.
12．Fei Tian, Yongtao Tang*, Kai Zhao#. Characterization of the complete mitochondrial genome ofGymnocypris scleracanthus(Teleostei: Cyprinidae). Conservation Genetics Resources, 2017,1-3.
13．Kunyuan Wanghe, Yongtao Tang, Fei Tian, Chenguang Feng, Renyi Zhang, Sijia Liu, Kai Zhao#. Phylogeography of Schizopygopsis stoliczkai (Cyprinidae) in Northwest Tibetan Plateau area. Ecology and Evolution, 2017, 7: 9602-9612.
14．Fei Tian, Chao Tong, Chenguang Feng, Kunyuan Wanghe, Kai Zhao#. Transcriptomic profiling of Tibetan highland fish (Gymnocypris przewalskii) in response to the infection of parasite ciliate Ichthyophthirius multifiliis. Fish & shellfish immunology, 2017, 70: 524-535.
15．Chenguang Feng, Yongjie Wu, Fei Tian, Chao Tong, Kai Zhao#. Elevational diversity gradients of Tibetan loaches: The relative roles of ecological and evolutionary processes. Ecology and Evolution, 2017, 7: 9970-9977.
16．Cunfang Zhang, Kai Zhao#. Integrated mRNA and microRNA transcriptome analyses reveal regulationin Tibetan Schizothoracine fish. PLOS One, 2017, 12(10): e**.
17．Chao Tong#, Fei Tian, Kai Zhao#. Genomic signature of highland adaptation in fish: a case study in Tibetan Schizothoracinae species. BMC Genomics, 2017, 18: 948.
18．Guogang Li, Zuogang Peng, Renyi Zhang, Yongtao Tang, Chao Tong, Chenguang Feng, Cunfang Zhang, Kai Zhao#. Mito-nuclear phylogeography of the cyprinid fish Gymnodiptychus dybowskii in the arid Tien Shan region of Central Asia. Biological Journal of the Linnean Society, 2016, 118(2): 304-314.
19．Guogang Li, Yongtao Tang, Renyi Zhang, Kai Zhao#. Phylogeography of Diptychus maculatus (Cyprinidae) endemic to the northern margin of the QTP and Tien Shan region. BMC Evolutionary Biology, 2016, 16(1): 186.
20．Renyi Zhang, Yongtao Tang, Cheng Feng, Kai Zhao#. Comparative cytogenetics of two sympatric species (Gymnocypris, Schizothoracinae) from the Lake Langcuo, Qinghai-Tibet Plateau. Caryologia, 2016, 69(3): 196-200.
21．Renyi Zhang, Kai Zhao#. Isolation and characterization of ten polymorphic microsatellite loci from Gymnocypris chui and cross-amplification in seven highly specialized Schizothoracinae fishes. Journal of Applied Ichthyology, 2016, 32(4): 718-720.
22．Yongtao Tang, Chenguang Feng, Kunyuan Wanghe, Guogang Li, Kai Zhao#. Taxonomic status of a population of Gymoncypris waddelli Regan, 1905 (Cypriniformes: Schizothoracinae) distributed in Pengqu River, Tibet, China. Zootaxa, 2016, 4126(1): 123-137.
23．Chao Tong, Fei,Tian Yongtao Tang, Chenguang Feng, Lihong Guan, Cunfang Zhang, Kai Zhao#. Positive Darwinian selection within interferon regulatory factor genes of Gymnocypris przewalskii (Cyprinidae) on the Tibetan Plateau. Fish & shellfish immunology, 2016, 50: 34-42.
24．Chao Tong, Kai Zhao #. Signature of adaptive evolution and functional divergence of TLR signaling pathway genes in Tibetan naked carp Gymnocypris przewalskii. Fish & Shellfish Immunology, 2016, 53, 94-124.
25．Renyi Zhang, Arne Ludwig, Cunfang Zhang, Zuogang Peng#, Kai Zhao#. Local adaptation and ecological speciation of Gymnocypris przewalskii (Cyprinidae) on the Tibetan Plateau. Scientific Reports, 2015, 5: 9780.
26．Chao Tong, Cunfang Zhang, Kai Zhao#. Transcriptome profiling analysis of naked carp (Gymnocypris przewalskii) provides insights into the immune-related genes in highland fish. Fish & Shellfish Immunology, 2015, 46(2): 366-377.
27．Chao Tong, Yaqiu Lin, Cunfang Zhang, Jianquan Shi, Hongfang Qi, Kai Zhao#. Transcriptome-wide identification, molecular evolution and expression analysis of Toll-like receptor family in a Tibet fish, Gymnocypris przewalski. Fish & Shellfish Immunology, 2015, 46(2): 334-345.
28．Chao Tong, Cunfang Zhang, Jianquan Shi, Hongfang Qi, Renyi Zhang, Yongtao Tang, Guogang Li, Chenguang Feng, Kai Zhao#. Characterization of two paralogous myostatin gene and evidence for positive selection in a Tibet fish: Gymnocypris przwalskii. Gene, 2015, 565(2): 201-210.
29．Delin Qi#, Songchang Guo, Yan Chao, Qinghui Kong, Kai Zhao#. The biogeography and phylogeny of schizothoracine fishes (Schizopygopsis) in the Qinghai-Tibetan Plateau. Zoologica Scripta, 2015, 44(5): 523-533.
30．Renyi Zhang, Zuogang Peng, Xiaoni Gan, Sunping He, Kai Zhao#. Ongoing Speciation in the Tibetan Plateau Gymnocypris Species Complex. PLoS One, 2013, 8(8): e71331.
31．Kai Zhao, Ziyang Duan, Zuogang Pen, Xiaoni Gan, Renyi Zhang, Sunping He, Xinquan Zhao#. Phylogeography of the endemic Gymnocypris chilianensis (Cyprinidae): Sequential westward colonization followed by allopatric evolution in response to cyclical Pleistocene glaciations on the Tibetan Plateau. Molecular Phylogenetics and Evolution, 2011, 59(2): 303-310.
32．Kai Zhao, Ziyang Duan, Songchang Guo, Junbing Li, Sunping He, Xinquan Zhao#. The youngest split in sympatric Gymnocypris (Cyprinidae) is shaped by ecological adaptations in the Tibetan Plateau glacier lake. Molecular Ecology, 2009, 18: 3616-3628.
33．Ziyang Duan, Kai Zhao, Zuogang Peng, Junbing Li, Rui Diogo, Xinquan Zhao, Sunping He#. Comparative phylogeography of the Yellow River schizothoracine fishes (Cyprinidae): vicariance, expansion, and recent coalescence in response to the Quaternary environmental upheaval in the Tibetan Plateau. Molecular Phylogenetics and Evolution, 2009, 53: 1025-1031.
34．Kai Zhao, Ziyuan Duan, Gongshe Yang, Zuogang Peng, Sunping He, Yiyu Chen#. Origin of Gymnocypris przewalskii and phylogenetic history of Gymnocypris eckloni (Teleostei: Cyprinidae). Progress in Natural Science, 2007, 17: 520-528.
35．Kai Zhao, Junbing Li, Gongshe Yang, Ziyuan Duan#. Molecular phylogenetics of Gymnocypris (Teleostei: Cyprinidae) in Lake Qinghai and adjacent drainages. Chinese Science Bulletin, 2007, 50(13): 1325-1333.



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