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内蒙古民族大学蒙医药学院导师教师师资介绍简介-付明海

本站小编 Free考研考试/2021-06-24

付明海
学术学位硕士生导师

副教授
**


mfu@imun.edu.cn

蒙医药学院






个人简介

付明海,男,蒙古族,中国共产党员,2013年4月-2017年9月澳大利亚昆士兰大学分子营养学博士,昆士兰大学国际奖学金(UQI)获得者。2015年9月-2015年12月在法国国家农业科学研究院(INRA)从事合作课题研究。2017年9月博士毕业后入职内蒙古民族大学蒙医药学院,现任蒙医药学院教职工第一支部书记,内蒙古民族大学蒙医药研究所所长,副教授,硕士研究生导师。内蒙古民族大学青年****创新联盟副会长,世界中医药学会联合会蒙医药专业委员会常务理事,中国民族医药协会蒙医药专业委员会常务理事,中国民族医药学会信息与大数据分会理事,全国保健服务标准化技术委员会专家等。发表期刊论文及国际会议论文等30余篇,国际国内会议上做学术报告12次,主持国家自然科学基金和内蒙古自然科学基金,及国家人社部赤子计划项目等10余项课题。承担本科专业《药学英语》、《蒙医养生学》与《药事管理》等课程。主要研究方向为揭示化学感应机制(味觉和嗅觉)如何调节人和实验动物的食物摄取、能量代谢以及在相关代谢性疾病中的调控作用,如肥胖症、糖尿病等。在此基础上,以味觉受体功能研究蒙中药药性药味理论的科学内涵。此外,团队还致力于研发基于蒙医药特色的健康保健产品。
学习和工作经历
2004.9-2005.7- 内蒙古民族大学蒙医药学院,药物制剂专业,本科
2005.9-2008.7- 沈阳药科大学(委托培养),药物制剂专业,本科
2006.7-蒙古国国立医科大学访问交流(蒙古)
2008.9-2011.7-内蒙古民族大学蒙医药学院中(蒙)药学硕士研究生
2013.4-2017.9-澳大利亚昆士兰大学(2015 QS世界排名第43)博士研究生
2013.8-澳大利亚新西兰营养学会年会(布里斯班)
2013.12与2014.9-澳大利亚最大肉猪企业RIVALEA合作项目(墨尔本)
2014.1-澳大利亚阿德莱德大学进行两周交流学习(阿德莱德)
2014.12-AACSS澳大利亚-亚洲化学感知学术年会(布里斯班)
2015.9-2015.12-法国农业科学院科研合作项目(法国雷恩)
2016.6-ISOT味觉与嗅觉年会(日本横滨)
2016.10-顺利完成博士论文毕业答辩,11项答辩评分标准被学术委员会给予全部优秀通过。博士毕业论文被美国爱荷华大学教授John F Patience 评价为“This is one of the most outstanding graduate student works that I have read with regard to the process of scientific discovery”。
2017.9 - 今,就职于内蒙古民族大学蒙医药学院
获奖状况
2005.6-内蒙古民族大学二等奖学金
2011.7-内蒙古民族大学优秀硕士毕业论文
2014.1-Pork CRC 奖学金:3000澳元
2014.10-昆士兰大学学费及生活费奖学金:每年约57300澳元
2015.6-昆士兰大学研究生处国际差旅奖学金(GSITA):5000澳元
2015.10-昆士兰大学QAAFI差旅奖学金:2500澳元
2016.12-昆士兰大学RHD生活补助奖学金:2576澳元
2017.4-澳大利亚Australian Pork Limited (APL) 差旅奖学金:1000澳元
2019.9-内蒙古民族大学“科尔沁****”
2019.11-第15届中国药理学会年会“优秀青年****英文学术报告”三等奖(北京)
2020.7-国家教育部民族教育发展中心《首届民族教育优秀教学成果奖》(团队骨干)






科研项目
1. 国家自然科学基金青年项目,**,蒙药肋柱花对高脂饮食诱导肥胖大鼠的减肥功效及其苦味机制研究,2019.01-2021.12,20万元,在研,主持
2. 内蒙古自然科学基金面上项目,2018MS08040,蒙药肋柱花减肥作用机制研究,2019.01-2021.12,6万元,在研,主持
3. 内蒙古自治区人才开发基金项目,蒙药苦味药性功能的生物学基础研究,2018.01-2020.12,2万元,在研,主持
4. 内蒙古自治区本科直属高校2019年“双一流”建设专项资金蒙药科研创新团队建设项目,《内蒙古自治区蒙药食药源保护与利用创新团队》建设项目,2019.09-2021.09, 150万,负责人
5. 内蒙古自治区高等学校科学技术研究项目重点项目,NJZZ18153,蒙药肋柱花调节胃肠道动力功能及其苦味机制研究,2018.1-2020.12,6万元,在研,主持
6. 内蒙古民族大学博士科研启动基金,BS412,8种地格达类蒙药对肥胖大鼠模型的减肥功效评价及苦味机制研究,2018.1-2020.12,20万元,在研,主持
7. 内蒙古自治区蒙药工程技术研究中心开放基金项目,MDK**,蒙药梅花草治疗肥胖症的苦味机制研究,2018.1-2019.12,7万元,在研,主持
8. 蒙医药标准化研究国际合作科技创新项目,MDKBZH**, 蒙药肋柱花的质量标准研究, 2018.01-2019.12, 5万元,在研,主持
9. 内蒙古自治区科技计划项目子课题,KJJH**,蒙药甜味药性功能的生物学基础研究,2018.01-2019.12,5万元,主持(已结题)
10.国家人社部2019年“海外赤子为国服务行动计划”--《海外赤子梦回草原,助力绿色蒙药发展》项目,2019.05-2019.10, 15万元,负责人(已结题)
11.The association between oral bitter taste sensitivity and intestinal drug absorption,国家民-教育部蒙医药研发工程重点实验室开放基金,2018.07-2020.06,15万元 (澳大利亚昆士兰大学国际合作项目,Eugeni Roura, Fu Minghai)
12.Berberine as an anti-inflammatory agent and its effects on the composition of gut microbiota,国家民-教育部蒙医药研发工程重点实验室开放基金,2018.07-2020.06,10万元 (澳大利亚新英格兰大学国际合作项目,Mingan Choct, Fu Minghai)
13.Historical Survey Of Mongolian Medical Tradition in China,国家民-教育部蒙医药研发工程重点实验室开放基金,2018.07-2020.06,10万元 (澳大利亚国立大学国际合作项目,Narangowa, Fu Minghai)


论文情况

中文论文
阿丽沙,付明海,张屏,包保全,哈斯其木格.HPLC测定四味土木香散中土木香内酯和异土木香内酯的含量[J].中国民族医药杂志,2011,17(04):56-57.
付明海,阿丽沙,包保全,张屏,赵德力格尔呼.蒙药材芹叶铁线莲对海虾幼虫的致死活性[J].内蒙古民族大学学报,2011,17(02):79-80.
付明海. 蒙药材芹叶铁线莲生物活性成分研究[D].内蒙古民族大学,2011.
赵·德力格尔呼, 付明海, 阿丽沙, 张屏, 包保全. 蒙药材黄花铁线莲抗肿瘤活性成分研究,中国保健营养,2012, (4), 297-299.
张屏,吉日木巴图,赵德力格尔呼,付明海,包保全.蒙药材特木日-敖日秧古的研究进展[J].现代药物与临床,2013,28(03):435-440.
特日格乐,阿丽沙,付明海,靳文杰,巴根那.治疗肥胖症的研究进展[J].内蒙古民族大学学报,2018,01: 38-45.
特日格乐,阿丽沙,付明海,靳文杰,巴根那.简述蒙医药理论中的六味对肥胖症的影响[J].科学认知东方传统医学杂志,2018,15(05): 141-146.
特日格乐,付明海,阿丽沙,靳文杰,戴丽丽,苏日嘎拉图,吉小平,李慧芳,巴根那.味觉受体细胞及胃肠道味觉感受.中国民族医药协会蒙医药专业委员会成立大会暨首届学术年会论文集[C]. 北京,2018:700-703.
吉小平,阿丽沙,于红珍,李慧芳,巴根那,付明海*.蒙药方剂配伍研究概况[J].中国民族民间医药,2021,30(02):55-58.
吉小平,阿丽沙,李慧芳,付明海,巴根那. (2020) 基于Ussing chamber、Caco-2以及药味药性研究的蒙药配伍研究进展. 内蒙古民族大学学报(蒙医药学)2020::10-27
于红珍,付明海*,吉小平,额尼荣贵.简述胃肠动力调节机制的研究进展[J].世界华人消化杂志,2020,28(23):1183-1191.
李慧芳,阿丽沙,付明海,拉喜那木吉拉.蒙药学一流专业建设思路初探——以内蒙古民族大学为例[J].亚太传统医药,2020,16(11):221-223.
阿丽沙,包明兰,王秀梅,斯日棍其其格,李慧芳,付明海*.蒙药炮制学教学改革初探[J].中国民族医药杂志,2020,26(12):41-42+76.
杨立国,阿丽沙,敖日格乐,白梅荣,付明海*.(2020)等温滴定微量热法及其在中药研究中的应用. 内蒙古民族大学学报 (审稿中)
英文期刊论文
Fu M.,Collins C. L., Henman D. J., Roura E. (2015) Some bitter compounds show potential for decreasing feed intake and fat deposition while others improve growth and feed conversion ratio in finishing pigs. Animal Production Science 55, 1543–1543
E. Roura and M. Fu. (2017) Taste, nutrient sensing and feed intake in pigs (130 years of research: then, now and future). Animal Feed Science and Technology 233, 3–12.
Lijun Sun, Dongjie Liu, Jiaojiao Sun, Xingbin, Yang, Minghai Fu*and Yurong Guo*. (2017) Simultaneous separation and purification of chlorogenic acid, epicatechin, hyperoside and phlorizin from thinned young Qinguan apples by successive use of polyethylene and polyamide resins. Food Chemistry, 230: 362-371(通讯作者)
Sun, L., Sun, J., Liu, D., Fu, M., Yang, X., & Guo, Y. (2018). The preservative effects of chitosan film incorporated with thinned young apple polyphenols on the quality of grass carp (Ctenopharyngodon idellus) fillets during cold storage: Correlation between the preservative effects and the active properties of the film. Food Packaging and Shelf Life, 17, 1-10.
Tang N, Ting V, Fu M, Roura, E. The expression of bitter taste receptors (T2Rs) in the porcine gastrointestinal tract epithelium and smooth muscle [J]. Animal Production Science, 2017, 57(12): 2420-2420.
Wang J, Fu M, Navarro M, et al. A double-choice model to quantify negative preference to bitterness in pigs[J]. Animal Production Science, 2017, 57(12): 2422-2422.
Han, Pengfei, Bagenna Bagenna, and Minghai Fu*."The sweet taste signalling pathways in the oral cavity and the gastrointestinal tract affect human appetite and food intake: a review."International journal of food sciences and nutrition70.2 (2019): 125-135.
Coquery, Nicolas, Paul Meurice, Regis Janvier, Eric Bobillier, Stephane Quellec, Minghai Fu, Eugeni Roura, Herve Saint-jalmes, and David Val-Laillet. "fMRI-based brain responses to quinine and sucrose gustatory stimulation for nutrition research in the minipig model: a proof of concept study."Frontiers in Behavioral Neuroscience12 (2018): 151.
Yu HZ, A LS, Ji XP, Cho SB, Ba GN, Han PF, Fu MH*. Bitter components related to alleviating intestinal obstruction in Traditional Mongolian medicine. TMR Theory and Hypothesis 2020, 3(2):337 -347.
Sun, L., Song, Y., Chen, Y., Ma, Y., Fu, M*., & Liu, X. (2021). The galloyl moiety enhances the inhibitory activity of catechins and theaflavins against α-glucosidase by increasing the polyphenol–enzyme binding interactions.Food & Function,12(1), 215-229.
Minghai Fu, Xiaoping Ji, Alisha, Bagenna. (2020) Property and flavor compatibility studies in traditional Chinese medicine formulabased on Ussing chamber and Caco-2 cells . Evidence-based complementary and alternative medicine (审稿中)
Shan Tong, Huan Wang, Lisha A, Tana Bai, Juhua Gong, Genna Ba,Sungbo Cho* and Minghai Fu*.(2020) The protective effect and molecular mechanisms of Traditional Mongolian medicine Sulongga-4 on pyloric-ligation induced gastric-duodenal ulcer in rats by microarray analysis. World Journal of Gastroenterology (minor revision)
Terigele Bao, Wenjie jin, Lili Dai, Hongzhen Yu, Xiaoping Ji, Sungbo Cho, Ba Genna and Minghai Fu*.(2020)Anti-obesity effect and regulation of gastrointestinal function of Mongolian Medicine Lomatogonium rotatum on high-fat high-sugar diet induced obese rats.Phytomedicine (审稿中)
Minghai Fu, Alisha, Siriguleng.(2020)Morphological and seed germination behavior of three Herba Swertiae species from Hulunbuir Inner Mongolia: temperature and culture medium effects. Journal of Herbs, Spices & Medicinal Plants (审稿中)

国际会议论文或摘要
Roura E, Guzmán-Pino S A, Fu M. The taste system from chickens to humans: a common link in search for a nutritionally balanced diet[C]//Proceedings of the 34th Western Nutrition Conference-processing, performance and profit, Saskatoon, Saskatchewan, Canada, 24-26 September, 2013. Western Nutrition Conference Planning Committee, 2013: 29-41.
Fu M, Guzman-Pino S A, Roura E. Dietary bitterness reduces feed intake in piglets with or without gastrointestinal discomfort conditioning[C]//Chemical Senses. GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND: OXFORD UNIV PRESS, 2015, 40(3): 273-274.
M. Fu, C. Collins, D. Henman and E. Roura (2014) Bitter. Animal Science Olympic poster competition. QAAFI, The University of Queensland, September 2014.
M. Fu, C. Collins, D. Henman and E. Roura (2014) Dietary manipulation of feed intake in pigs by bitter compounds. QAAFI Annual Research Meeting (ARM) 2014, The University of Queensland, November 2014.
M. Fu, C. Collins, D. Henman and E. Roura (2014) Dietary manipulation of feed intake in pigs by bitter compounds. The 15th Scientific Meeting of the Australasian Association for ChemoSensory Science (AACSS). December 3-5, Brisbane, Australia.
M.Fu and E.RouraSweet potential of bitter taste in treating obesity.The First Mongolian Medicine Industry Expo and the Eurasian Pacific University Alliance Mongolian Medicine Academic Summit. August 19-21, 2015, Tongliao, China.
M. Fu, C. Collins, D. Henman, J. Kim and E. Roura (2015) Effects of bitter compounds on growth performances and carcass traits in finishing pigs. The 1stTropical Agriculture Conference 2015 (TropAg 2015). November 16-18, Brisbane, Australia.
M. Fu, C. L Collins, D. J Henman and E. Roura (2015) Bitter taste compounds decreased feed intake and fat deposition or improved growth and feed conversion efficiency in immunocastrated finishing pigs. Australasian Pig Science Association Manipulating Pig Production. November 22-25, Melbourne, Australia.
E. Roura andM. Fu(2015) Bitter compounds decrease gut motility, appetite and fat deposits in a pig model. The 16th Scientific Meeting of the Australasian Association for ChemoSensory Science (AACSS). December 2-4, Canberra, Australia.
Fu M, Manchadi M L, De Jager N, et al. Bitter compounds delayed gastric emptying and induced intestinal smooth muscle relaxation in a pig model[C]//17. International Symposium on Olfaction and Taste (ISOT2016). 2016, 41(9): np.
E. Roura and M. Fu“Bitter” The second Mongolian Medicine Industry Expo and the Eurasian Pacific University Alliance Mongolian Medicine Academic Summit. August 16-19, 2016, Tongliao, China.
Ji Wang,Minghai Fu, Marta Navarro and Eugeni Roura (2016) A double-choice model to quantify negative preferences due to bitterness in pigs. The 17th Scientific Meeting of the Australasian Association for ChemoSensory Science (AACSS). December 2-3, Eveleigh, Sydney, Australia.
Huan Wang, Minghai Fu,Tuul Khalzaabaast, Mei Hong, Genna Ba.(2017) Pylorus Ligation Induces Liver Injury via Modulating the Expression of Bile Acids Metabolic Proteins in Rats. The conference of the establishment of the expert committee of Mongolian Medicine of World Federation of Chinese Medicine Societies and the first acedemic Forum, Tongliao, July 15th-17th.
Minghai Fu, Alisha, Ping Zhang and Baoquan Bao. (2017) Flavonoids from Clematis aethusifolia Turcz. The conference of the establishment of the expert committee of Mongolian Medicine of World Federation of Chinese Medicine Societies and the first acedemic Forum, Tongliao, July 15th-17th.
M. Fu, D. Val-Laillet, S. Guerin and E. Roura. (2018) Dietary bitter compounds delayed gastric emptying and glucose uptake while increased plasma insulinotropic hormone GLP-1 in pigs. Digestive Physiology of Pig, Brisbane, August 20th-24th.
M. Fu, Alisha, H. Li, T. Bao, W. Ao and Bagenna. (2018) Bitter taste physiology in mammals. The founding conference of specialty committee of Mongolian Medicine of CEMA & The first academic conference, Beijing, July 27th – 29th.
M. Fu, Alisha, H. Li, T. Bao, W. Ao and Bagenna. (2018) Medicinal herb derived bitter substances affect appetite and feed intake through bitter taste signalling mechanism in a pig model. The founding conference of specialty committee of Mongolian Medicine of CEMA & The first academic conference, Beijing, July 27th – 29th.
M. Fu, Alisha, E. Duleng, H. Wang, W. Ao and Bagenna. (2018) Sweet taste and food intake regulation. The founding conference of specialty committee of Mongolian Medicine of CEMA & The first academic conference, Beijing, July 27th – 29th.
M. Fu, Alisha, H. Li, T. Bao, L. Dai, W. Ao and Bagenna. (2018) The functional expression of bitter taste receptors in the oral and extraoral tissues. The founding conference of specialty committee of Mongolian Medicine of CEMA & The first academic conference, Beijing, July 27th – 29th.
FU, Minghai, Eugeni, David,VAL-LAILLET,Genna,BA.(2019)Bitter compounds delay gastric emptying while affecting plasma hormone profiles and duodenal nutrient absorption in a pig model[J]. 中国药理学与毒理学杂志, v.33(10):6-7.



成果奖励

2005.6-内蒙古民族大学二等奖学金
2011.7-内蒙古民族大学优秀硕士毕业论文
2014.1-Pork CRC 奖学金:3000澳元
2014.10-昆士兰大学学费及生活费奖学金:每年约57300澳元
2015.6-昆士兰大学研究生处国际差旅奖学金(GSITA):5000澳元
2015.10-昆士兰大学QAAFI差旅奖学金:2500澳元
2016.12-昆士兰大学RHD生活补助奖学金:2576澳元
2017.4-澳大利亚Australian Pork Limited (APL) 差旅奖学金:1000澳元
2019.9-内蒙古民族大学“科尔沁****”
2019.11-第15届中国药理学会年会“优秀青年****英文学术报告”三等奖(北京)
2020.7-国家教育部民族教育发展中心《首届民族教育优秀教学成果奖》(团队骨干)
2020.10-国家留学基金委CSC访问****奖学金


指导研究生情况(近五年)
包特日格乐.苦味蒙药地格达对高脂高能量饮食诱导肥胖症大鼠的减肥作用研究. 2017届硕士研究生
于红珍. 蒙药肋柱花对小鼠胃肠功能的调节作用及其机制研究. 2018届硕士研究生
吉小平.蒙药肋柱花对高脂饮食诱导肥胖小鼠的肠道微生物和营养吸收的影响及其减肥机制研究. 2018届硕士研究生
鲍东明. 基于地格达-4味汤入血成分的固定剂量组合药物药效学基础研究. 2019届硕士研究生
额尼荣贵. 蒙药肋柱花苦味素制备工艺及3T3-L1细胞增值和分化的影响. 2019届硕士研究生
苏日娜. 蒙医三根体质味觉感知评价. 2019届硕士研究生


团队主要成员
1. Sungbo Cho 澳大利亚昆士兰大学博士,讲师,专业方向:分子生物学,基因组学
2. 塔娜 澳大利亚昆士兰科技大学,讲师,专业方向:植物化学
3. 李慧芳 中央民族大学,助教,专业方向:细胞分子生物学
4. 阿丽沙,内蒙古民族大学,助教,专业方向:蒙药学
5. 靳文杰,2018届博士研究生
6. 戴丽丽,2018届博士研究生
7. 包特日格勒,2019届博士研究生



主讲课程
1. 药事管理-本科生
2. 药学英语-本科生
3. 蒙医养生学-本科生

知识产权
1. 肋柱花提取物及其制备方法、药物组合及减肥用途,付明海等,专利号:1.0(发明专利)
2. 苦地丁提取物及其组合物和减肥用途及制剂,付明海等,专利号:7.X(发明专利)
3. 一种文冠果油保健奶茶,付明海等,专利号:1.4(发明专利)
4. 一种保健奶茶及其制备方法,付明海等,专利号:3.1(发明专利)


著作教材
1. 《中国蒙医药古籍影印珍本》参编, 辽宁民族出版社,75万字,2018年
2. 《蒙药药理学博士生教材》副主编,辽宁民族出版社,58万字,2019年
3. 《蒙药实验药理学教材》参编,在研
4. 《苦味受体功能与蒙药苦味药性》专著,在研






研究方向
蒙药药味药性现代化研究;蒙药食药源保护与利用研究;蒙药创新药物研发
相关话题/内蒙古民族大学 医药学院