阿拉坦高勒（常用名：高勒）
教授，博士生导师。日本群马大学博士，美国亚利桑那州立大学高级访问****。学术兼职有内蒙古生化与分子生物学分会副理事长，中国生化与分子生物学学会脂质与脂蛋白专业委员，日本群马大学分子与细胞调节学研究所客座研究员、《现代生物医学进展》杂志编委。自回国以来，主持国家自然科学基金项目5项、内蒙古新技术研发项目和教育部博士点基金项目等省部级基金项目6项.发表研究论文90余篇（其中SCI论文26篇），累计影响因子超过100，总引用率超过1000次。

研究兴趣
生理活性脂质G-蛋白偶联受体（GPCRs）介导的信号通路的调控与疾病（如肿瘤，动脉硬化等）之间关系；质子感知受体在酸性环境中所起的生理、病理作用及其信号机制。

代表性论文
1.Peng-fei Zhao, Shuang Wu,Ya Li Yan,Gegentuya Bao, Jingyuan Pei , Yue-wu Wang a,c , Qing Ma , Hong-ju Sun , Alatangaole Damirin*.. LPA receptor1 antagonists as anticancer agents suppress human lung tumours European Journal of Pharmacology.18 Dec 2019 accepted .(SCI IF3.1，三区)
2.Liang Bao Jingwei Qi c , 1 , Yue-wu Wang a , 1 , Qilemuge Xi a ,Tseveensuren Tserennadmid , Peng-fei Zhao a , Jerry Qi d , Alatangaole Damirin a ,The atherogenic actions of LPC on vascular smooth muscle cells and itsLPA receptor mediated mechanism Biochemical and Biophysical Research Communications (2018) 8
3. Li N, Yan YL, Fu S, Li RJ, Zhao PF, Xu XY, Yang JP,Damirin A .*Lysophosphatidic acid enhances human umbilical cord mesenchymal stem cell viability without differentiation via LPA receptor mediating manner.Apoptosis. 2017 Oct;22(10):1296-1309.
4. Gao X, Zhai M, Guan W, Liu J, Liu Z*,Damirin A ；Controllable Synthesis of a Smart Multifunctional Nanoscale Metal-Organic Framework for Magnetic Resonance/OpticalImaging and Targeted Drug Delivery.ACS Appl Mater Interfaces.2017 Feb 1;9(4):
5. Fengrui Li1,2, Biao Ge3, Alatangaole Damirin Overexpression of p58ipk protects neuroblasto- maagainst paraquat-induced toxicityInt J Clin Exp Pathol 15 August 2017
6. An C,Sato K,Wu T,Bao M,Bao L,Tobo M,Damirin A. Extracellular Acidification Synergizes with PDGF to Stimulate Migration of Mouse Embryo Fibroblasts through Activation of P38MAPK with a PTX-Sensitive Manner.Biochem Biophys Res Commun.2015 Mar 10. pii: S0006-291X(15)00431-3.
7.QilemugeXi,Dengzhi Yang,Liang Bao, Damirin Alatangaole； TDAG8-mediated intracellular signaling pathways and its function on tumor ICBAEE 2014，Toylor & Francis Group ICBAEE 2014 ,22-25
8.Yang De-zhi Yang Wen-hua Zhang Qian Alatangaole Damirin；Migration of the gastric cancer cell in response to lysophosphatidic acid is mediated by LPA receptor 2，Oncology Letters2013 Mar;5(3):1048-1052
9.Gui-Jun Zhao,Li-Xia Xu,Eagle SH Chu,Ning Zhang,Jia-Yun Shen,Alatangaole Damirin, andXiao-Xing Li；Establishment of an orthotopic transplantation tumor model of hepatocellular carcinoma in miceWorld J Gastroenterol.2012 Dec 21; 18(47): 7087–7092.
10.Mayumi Komachi¹；Alatangaole Damirin¹；Chihiro Mogi；Masayuki Tobo；Hideo Ohta；Koichi Sato；Hideaki Tomura；Fumikazu Okajima*: Signalingpathways involved in DNA synthesis and migration in response to lysophosphatidic acid and low-density lipoprotein in coronary artery smooth muscle cells Vascular Pharm 50 (2009)178–184
11.Damirin A, Tomura H, Komachi M, Liu JP, Mogi C, Tobo M, Wang JQ, Kimura T, Kuwabara A, Yamazaki Y, Ohta H, Im DS, Sato K, Okajima F*. Role of lipoprotein-associated l yophospho- lipids in migratory activity of coronary artery smooth muscle cells.Am J Physiol 2007 Jan 19 12.Damirin A, Tomura H, Komaci M, Tobo M, Sato K, Mogi C Nochi H Tamoto K, Okajima F*，Sphingosine 1-phosphate receptors mediate the lipid-induced cAMP accumulation through cyclooxygenase-2/prostaglandin I2 pathway in human coronary artery smooth muscle cells.. Mol. Pharmacol.67:1177-1185. (2005)
联系地址：内蒙古呼和浩特市玉泉区昭君路24号（010070）生命科学学院
电话（传真）：0086-, 邮箱;bigaole@imu.edu.cn