导师简介
导师姓名李艳春性别女出生年月1971.10导师类别硕导
研究方向抗肿瘤药理学
联系电话**；**职称/院士副教授
E-mailliyanchun213325@163.com导师学位博士
学院（工作单位）生命科学与生物制药学院
信箱（地址）沈阳药科大学41号信箱

李艳春，女，1971年10月25日生，副教授，硕士生导师，博士。2002年毕业于沈阳药科大学获得药理学硕士研究生2010年毕业于沈阳药科大学获理学博士学位， 2003 ～ 至今在沈阳药科大学药理教研室任教。研究方向：抗肿瘤药理、新药药理与毒理学，主要进行抗肿瘤活性化合物的筛选及其抗肿瘤药物抗肿瘤作用机制研究，并且可进行新药药理学临床前研究及毒理学研究。

发表文章：

1、JNK mediates asperphenamate derivative BBP-induced autophagy in MCF-7 cells, Toxicol Appl Pharm，2012, 263: 21-31. IF 4.447

2、The induction of G2/M cell-cycle arrest and apoptosis by cucurbitacin E is associated with increased phosphorylation of eIF2a in leukemia cells, Anti-Cancer Drugs，2012, 90: 962-967. IF 2.376

3、β-Eudesmol Induces JNK-Dependent Apoptosis through the Mitochondrial Pathway in HL60 Cells, Phytotherapy Research，2010, 21:389–400. IF 2.086

4、Discovery of asperphenamate derivative as autophagy inducer for MCF-7 breast cancer cellsSynthesis and in vitro antitumor activity of asperphenamate derivatives as autophagy inducer, Bioorganic Medicinal Chemistry Letters, 2012,22: 215–2219. IF2.554

5、Synthesis and in vitro antitumor activity of asperphenamate derivatives as autophagy inducer Pentamethoxyflavan induces arrest of G2/M phase and mitochondrial-mediated cell apoptosis in HL60 cell, Toxicology in Vitro，2009,23(5), 74-879. IF 2.775

6.1-(3',4',5'-Trimethoxyphenyl)-3-(3'',4''-dimethoxy-2''-hydroxyphenyl)-propanewith microtubule-depolymerizing ability induces G2/M phase arrest and apoptosis in HepG2 cells. Chem-Bio Interactions，2010,188(1):161-170 IF 2.832

7、Induction of apoptosis by furanodiene in HL60 leukemia cells through activation of TNFR1 signaling pathway，Cancer Letters，2008,271, 158–166，IF 4.864

8、Activation of ATM-Chk2 by 16-dehydro pregnenolone induces G1 phase arrest and apoptosis in HeLa cells，Journal of Asian Natural Products Research，2012, 14: 817-825 IF 0.994

9、β-Eudesmol suppresses tumor growth through inhibition of tumor neovascularization and tumor cell proliferation, Journal of Asian Natural Products Research, 2008, 0:159-167 IF 0.994

[联系方式]

联系电话：**

E-mail：liyanchun213325@163.com