姓名： 吴志勇
职称： 教授
专业：分析化学
研究方向：微纳流控分析，纸基分析装置，生化分析，电泳，色谱
E-mail: zywu@mail.neu.edu.cn
办公电话：**
个人简历：1984年河北大学学士，1992年中科院兰州化物所博士，2000年瑞士洛桑联邦理工学院（EPFL）博士后；河北大学助教（1984）、讲师（1992）、副教授（1994）、教授（2001）。2003年至今东北大学教授。
学术成果（代表性论文、承担的项目等）：
现承担项目：国家自然科学基金面上项目 基于微纳界面浓度极化和分子穿孔效应的生物分析新方法研究 （**），2016.01-2019.12
代表性论文
1.Han Gao, Jia-Juan Liu, Xiu-Yu Fang and Zhi-Yong Wu. Detection of urine protein by a paper-based analytical device enhanced with ion concentration polarization effect. Microfluid Nanofluid 2019, 23: DOI:10.1007/s10404-019-2220-3
2.Lei Liu, Mao-Rong Xie, Yu-Zhu Chen and Zhi-Yong Wu. Simultaneous electrokinetic stacking and sepration of anionic and cationic species on a paper fluidic channel. Lob Chip 2019, 19, 845-850
3.Ting Zhou, Jia-Juan Liu, Ye Xu* and Zhi-Yong Wu*. Fast and sensitive screening detection of tetracyclines with a paper-based analytical device. Microchemical Journal 2019, 145, 703-707
4.Xiu-Xiu Zhang, Jia-Juan Liu, Yu Cai, Shuang Zhao* and Zhi-Yong Wu. A field amplification enhanced paper-based analytical device with a robust chemiluminescence detection module. Analyst 2019, 144, 498-503
5.王华杰，刘元敏，李光宇，吴志勇* 单个纳米孔电流脉冲法探究鱼精蛋白与单链DNA的相互作用. 分析化学（Chinese J Anal Chem），2018, 46(6):851-857.
6.孙珊珊，刘元敏，李光宇，吴志勇* 离子液体电解质对DNA穿过α-溶血素纳米孔的影响，分析化学（Chinese J Anal Chem），2018, 46(6):858-864. IP 0.709
7.Fang Fang, Yan-Qin He, Li Tian, Yun-Yun Li, Zhi-Yong Wu*. Making of a single solid-state nanopore on the wall of fused silica capillary. Roy Soc Open Sci.2018，5: 171633. http://dx.doi.org/10.1098/rsos.171633
8.HanGao, Mao?RongXie, Jia?JuanLiu, FangFang, Zhi?YongWu*. Electrokinetic stacking onpaper?based analytical device byion concentration polarization withion exchange membrane interface. Microfluid Nanofluid. 201822:50 https://doi.org/10.1007/s10404-018-2071-3
9.Song-Fang Xie, Han Gao, Li-Li Niu, Zhen-Sheng Xie, Fang Fang, Zhi-Yong Wu* Fu-Quan Yang*. Carrier ampholyte-free isoelectric focusing on a paper-based analytical device for the fractionation of proteins.J Sep Sci. 2018, 41: 2085–2091. IP 2.741
10.Xiu-Xiu Zhang, Yi-Zhen Song, Fang Fang, Zhi-Yong Wu*. Sensitive paper-based analytical device for fast colorimetric detection of nitrite with smartphone.Anal Bioanal Chem2018410:2665-2669. IP 3.331
11.Lei Liu, Mao-Rong Xie, Fang Fang, Zhi-YongWu*. Sensitive colorimetric detection of Cu²⁺by simultaneous reaction and electrokinetic stacking on a paper-based analytical device. Microcheml J. 2018, 139: 357-362
12.Yi-Zhen Song, Xiu-Xiu Zhang, Jia-Juan Liu, Fang Fang, Zhi-Yong Wu*. Electrokinetic stacking of electrically neutral analytes with paper-based analytical device. Talanta 2018182: 247-252. IP 4.035
13.Ji-Cheng Niu, Ting Zhou, Li-Li Niu, Zhen-Sheng Xie, Fang Fang, Fu-Quan Yang*, Zhi-Yong Wu*. Simultaneous pre-concentration and separation on simple paper-based analytical device for protein analysis. Anal Bioanal Chem 2018410:1689-1695
14.Yi-Chen Song, Xiu-Xiu Zhang, Biao Ma, Zhi-Yong Wu*, Zi-Qiang Zhang* Performance of electrokinetic stacking enhanced paper –based analytical device wit smartphone for fast detection of fluorescent whitening agent. Anal Chim Acta, 2017, 995: 85-90. IP 4.725
15.Biao Ma, Song-Fang Xie, Lei Liu, Fang Fang, Zhi-Yong Wu*. Two orders of magnitude electrokinetic stacking of proteins on a simple paper fluidic channel. Anal Meth, 2017, 9:2703-2709
16.Zhi-Yong Wu*, Biao Ma, Song-Fang Xie, Kun Liu, Fang Fang, Simultaneous electrokinetic concentration and separation of proteins on a paper-based analytical device. RSC Adv., 2017, 7:4011-4016
17.Biao Ma, Yi-Zhen Song, Ji-Cheng Niu, Zhi-Yong Wu*. Highly efficient sample stacking by enhanced field amplification on a simple paper device. Lab Chip, 2016, 16:3460-3465
18.Fang Fang, Zhang Na, Liu Kun, and Wu Zhi-Yong*. Hydrodynamic and electrodynamic flow mixing in a novel total glass chip mixer with streamline herringbone pattern, Microfluid Nanofluid.2015, 18(5): 887-895
19.Zhang Da–Wei, Zhang Hui-Qin, Tian Li, Wang Lin, Fang Fang, Liu Kun and Wu Zhi-Yong*. Microfabrication-free fused silica nanofluidic interface for on chip electrokinetic stacking of DNA. Microfluid Nanofluid. 2013, 14(1-2): 69-76
20.Wu Zhi-Yong*, Fang Fang, He Yan-Qin, Li Ting-Ting, Li Jing-Jing, and Li Tian. Flexible and Efficient Eletrokinetic Stacking of DNA and Proteins at an HF Etched Porous Junction on a Fused Silica Capillary. Anal Chem2012, 84(16):7085-7091
21.Wu Zhi-Yong*, Li Cui-Ye, Guo Xiao-Li, Li Bo, Zhang Da-Wei, Xu Ye and Fang Fang. Nanofracture on fused silica microchannel for Donnan exclusion based electrokinetic stacking of biomolecules. Lab Chip2012, 12(18): 3408-3412
22.Min Kyoung-Ik, Lee Tae-Ho, Park Chan Pil, Wu Zhi-Yong, Girault Hubert H, Ryu Ilhyong, Fukuyama Takahide, Mukai Yu, Kim Dong-Pyo*. Monolithic and flexible polyimide film microreactors for organic microchemical applications fabricated by laser ablation, Angew Chemie(Int ed in Eng) 2010, 49(39): 7063-7
23.Qu Bai-Yan, Wu Zhi-Yong*, Fang Fang, Bai Zhi-Ming, Yang Dong-Zhi, Xu Shu-Kun. A glass microfluidic chip for continuous blood cell sorting by a magnetic gradient without labeling,Anal Bioanal Chem2008, 392(7): 1317-1324
24.Wu Zhi-Yong*, Chen Kun, Qu Bai-Yan, Tian Xiao-Xi, Wang Xiao-Jie and Fang Fang. A thermostat chip of indium tin oxide glass substrate for static polymerase chain reaction and in situ real time fluorescence monitoring, Anal Chim Acta2008, 610(1): 89-96
25.吴志勇*, 方芳. 电场耦合法芯片电泳柱上电导检测特性研究, 高等学校化学学报2008, 29(2): 283-287
26.Wang Ya-Rong, Li Jing-Jing, Wu Zhi-Yong*, Fan Jun-Gang and Fang Fang. Improvement of Porous Electro-conductive Membrane Preparation and Its Application in Sample Injection Pre-concentration in the Capillary Electrophoresis of Proteins, Chinese J Anal Chem（分析化学）2008, 36(7): 879-884
27.张娜, 方芳, 吴志勇*. 集成电极的复合混沌混合芯片的快速制备及表征, 功能材料与器件学报2008, 14(6): 943-948
28.Qu Bai-Yan, Wu Zhi-Yong*, Tian Xiao-Xi, Chen Kun and Fang Fang. Optimization of direct whole blood PCR amplification with applications on a static thermostat chip.(Author abstract)(Report), Anal Bioanal Chem 2007, 389(5): 1499-1504
29.Wu Zhi-Yong*, Fang Fang, Josserand Jacques and Girault Hubert H. On-column conductivity detection in capillary-chip electrophoresis, Electrophoresis2007, 28(24): 4612-4619
30.吴志勇*, 田晓溪, 渠柏艳, 陈坤, 方芳. 透明导电玻璃(ITO)基材自加热传感静态芯片聚合酶链反应(PCR)，高等学校化学学报2007, 28(12): 2259-2263
31.Zhang Tao, Fang Qun, Wang Shi-Li, Qin Li-Feng Wang Ping, Wu Zhi-Yong, Fang Zhao–Lun*. Enhancement of signal-to-noise level by synchronized dual wavelength modulation for light emitting diode fluorimetry in a liquid-core-waveguide microfluidic capillary electrophoresis system. Talanta 2005, 68(1): 19-24
32.Bai Xiao-Xia,Wu Zhi-Yong, Josserand J, Jensen H, Schafer H and Girault, H H*. Passive conductivity detection for capillary electrophoresis, Anal Chem2004, 76(11):3126-3131
33.Wu Zhi-Yong, Jensen Henrik, Gamby Jean, Bai Xiao-Xia and Girault Hubert H*. A flexible sample introduction method for polymer microfluidic chips using a push/pull pressure pump, Lab Chip2004, 4(5): 512-515
34.Lion Niels, Rohner Tatiana C, Dayon Lo?c, Arnaud Isabelle L, Damoc Eugen, Youhnovski Nikolay, Wu Zhi-Yong, Roussel Christophe, Josserand Jacques, Jensen Henrik, Rossier Jo?l S, Przybylski Michael and Girault Hubert H*. Microfluidic systems in proteomics, Electrophoresis 2003, 24(21): 3533-3562
35.Wu Zhi-Yong, Xanthopoulos Nicolas, Reymond Frédéric, Rossier Jo?l S and Girault Hubert H*. Polymer microchips bonded by O₂-plasma activation, Electrophoresis 2002, 23(5): 782-90