研究方向为功能纳米材料的制备，及其在分析检测、生物医用、能源催化等领域的应用。在Analytical Chemistry，Chemistry - A European Journal等国际期刊上发表高水平学术论文20余篇，授权国家发明专利5项，主持国家自然科学基金2项，辽宁省自然科学基金重点项目、沈阳市中青年科技创新人才支持计划等项目共4项，获评辽宁省高等学校创新人才，辽宁省百千万人才工程万层次人才，获得辽宁省自然科学学术成果奖、沈阳市自然科学学术成果奖多项。
个人经历：
2004/09 — 2008/06， 天津大学，材料科学与工程学院，学士；
2008/09 — 2013/06， 南开大学，化学学院，博士；
2013/10 — 2015/12， 辽宁大学，化学学院，讲师；
2015/12 — 2019/04， 辽宁大学，化学学院，副教授；
2019/04 — 现在， 辽宁大学，化学学院，副教授，博士生导师。
科研项目：
1、国家自然科学基金面上项目，“基于荧光聚离子符合胶束传感器阵列的奥兹海默症诊断研究”，主持（在研）；
2、国家自然科学基金青年基金项目，“基于聚合物修饰碳点的蛋白质荧光传感器阵列”，主持（结题）；
3、辽宁省自然科学基金材料联合基金，“基于纳米碳点的蛋白质荧光传感器阵列”，主持（在研）；
4、沈阳市中青年科技创新人才支持计划项目，“老年痴呆症诊断试剂盒的研究与开发”，主持（在研）；
5、横向课题项目，“防腐蚀类气体薄膜性能测试标准的建立”，主持（结题）。
研究成果：
1、Xiuping Tang, Xue Liu*, Yu Hou, Long Cai, Lijiang Chen, Qiuhua Wu, Jie Yi, and Guolin Zhang*, Various Concentrations of Carbon Nanodots Induced Fluorescent Calcite with Multi-morphologies, Crystal Growth & Design, 2018, 18, 6559–6563.
2、Yingying Li, Xue Liu*, Qiuhua Wu, Jie Yi and Guolin Zhang*, Discrimination and Detection of Benzaldehyde Derivatives Using Sensor Array Based on Fluorescent Carbon Nanodots, Sensors and Actuators B, 2018, 261, 271?278.
3、Yapei Wu, Xue Liu*, Qiuhua Wu, Jie Yi and Guolin Zhang*, Carbon Nanodots–Based Fluorescent Turn-on Sensor Array for Biothiols, Analytical Chemistry, 2017, 89, 7084?7089.
4、Yapei Wu, Xue Liu*, Qiuhua Wu, Jie Yi and Guolin Zhang*, Differentiation and Determination of Metal Ions Using Fluorescent Sensor Array Based on Carbon Nanodots, Sensors and Actuators B, 2017, 246, 680–685.
5、Xiuping Tang, Yu Hou, Guolin Zhang*, Xue Liu*, Thermo/pH dually responsive drug delivery systems based on mesoporous silica nanoparticles, Journal of Controlled Release, 2017, 259, e5–e195.
6、Qiuhua Wu, Yu Hou, Xue Liu*, Xiuping Tang, Hongyu Wang, Fengqing Hu, Ximing Song and Guolin Zhang*, Mixed Shell Mesoporous Silica Nanoparticles for Controlled Drug Encapsulation and Delivery, Nanomedicine, 2017, 12, 2699?2711.
7、 Yu Hou, Xue Liu*, Xiuping Tang, Tianze Li, Qiuhua Wu, Yuchun Jiang, Jie Yi and Guolin Zhang*, Nucleobase Chemosensor Based on Carbon Nanodots, Talanta, 2017, 173, 107–112.
8、Xue Liu, Tianze Li, Qiuhua Wu, Xiao Yan, Chenglin Wu, Xia Chen and Guolin Zhang*, Carbon Nanodots as a Fluorescence Sensor for Rapid and Sensitive Detection of Cr(VI) and Their Multifunctional Applications, Talanta, 2017, 165, 216–222.
9、Siyu Shi, Long Cai, Xue Liu, Haonan Li, Yuan Gao, Qiuhua Wu*, Jie Yi, Ximing Song and Guolin Zhang*, Bioinspired Fabrication of Macroporous Calcium Carbonate Crystals Mediated by Thermoresponsive Copolymers, RSC Advances, 2017, 7, 44505–44513.
10、Xue Liu, Songxue Wang, Jing Miao, Yang Liu, Xiao Yan* and Shunquan Chen*, Enhanced Performance of Fe2O3 Doped Yttria Stabilized Zirconia Hollow Fiber Membranes for Water Treatment, Ceramics International, 2016, 42, 15618–15622.
11、Xue Liu, Tianze Li, Yu Hou, Qiuhua Wu, Jie Yi and Guolin Zhang*, Microwave Synthesis of Carbon Dots with Multiresponse Using Denatured Proteins as Carbon Source, RSC Advances, 2016, 6, 11711–11718.
12、Xue Liu, Yu Hou, Xiuping Tang, Qiuhua Wu, Chenglin Wu, Jie Yi and Guolin Zhang*, Multicompartment Micelles Based on Hierarchical Co-assembly of PCL-b-PEG and PCL-b-P4VP Diblock Copolymers, RSC Advances, 2016, 6, 5312–5319.
13、Qiuhua Wu, Xiuping Tang, Xue Liu, Yu Hou, He Li, Chen Yang, Jie Yi, Ximing Song and Guolin Zhang*, Thermo/pH Dual Responsive Mixed-Shell Polymeric Micelles Based on the Complementary Multiple Hydrogen Bonds for Drug Delivery, Chemistry-An Asian Journal, 2016, 11, 112–119.
14、Xue Liu, Xiuping Tang, Yu Hou, Qiuhua Wu and Guolin Zhang*, Fluorescent Nanothermometers Based on Mixed Shell Carbon Nanodots, RSC Advances, 2015, 5, 81713–81722.
15、Tao Yin, Xue Liu, Jianzu Wang, Yingli An, Zhenkun Zhang* and Linqi Shi*, Thermosensitive Mixed Shell Polymeric Micelles Decorated with Gold Nanoparticles at the Outmost Surface: Tunable Surface Plasmon Resonance and Enhanced Catalytic Properties with Excellent Colloidal Stability, RSC Advances, 2015, 5, 47458–47465.
16、Xue Liu, Hongjun Gao, Fan Huang, Xiaodong Pei, Yingli An, Zhenkun Zhang* and Linqi Shi*, Structure Change of Mixed Shell Polymeric Micelles and Its Interaction with Bio-targets as Probed by the 1-anilino-8-naphthalene Sulfonate (ANS) Fluorescence, Polymer, 2013, 54, 3633–3640.
17、Xue Liu, Yang Liu, Zhenkun Zhang, Fan Huang, Qian Tao, Rujiang Ma, Yingli An and Linqi Shi*, Temperature-Responsive Mixed-Shell Polymeric Micelles for the Refolding of Thermally Denatured Proteins, Chemistry - A European Journal, 2013, 19, 7437–7442.
18、Qian Tao, Ang Li, Xue Liu, Hongjun Gao, Zhenkun Zhang, Rujiang Ma, Yingli An and Linqi Shi*, Improved Thermal Stability of Lipase in W/O Microemulsion by Temperature-Sensitive Polymers, Colloids and Surfaces B: Biointerfaces, 2013, 111, 587– 593.
19、Yaohua Gao, Cuihong Yang, Xue Liu, Rujiang Ma, Deling Kong* and Linqi Shi*, A Multifunctional Nanocarrier Based on Nanogated Mesoporous Silica for Enhanced Tumor-Specific Uptake and Intracellular Delivery, Macromolecular Bioscience, 2012, 12, 251–259.
20、Qian Tao, Ang Li, Xue Liu, Rujiang Ma, Yingli An and Linqi Shi*, Protecting Enzymes Against Heat Inactivation by Temperature-Sensitive Polymer in Confined Space, Physical Chemistry Chemical Physics, 2011, 13, 16265–16271.
发明专利：
1、一种用于荧光纳米温度计的复合壳层碳点及其制备方法和应用（ZL5.9）；
2、一种用于荧光纳米温度计的碳点的制备方法及其应用（ZL2.5）；
3、一种可提高酶热稳定性的高分子复合胶束及其制备和应用（ZL8.6）。
获得奖励：
1、辽宁省自然科学学术成果三等奖“Carbon Nanodots-Based Fluorescent Turn-On Sensor Array for Biothiols”
2、沈阳市自然科学学术成果二等奖“Microwave synthesis of carbondots with multiresponse using denatured proteins as carbon source”；
3、沈阳市自然科学学术成果三等奖“Fluorescent nanothermometers based on mixedshell carbon nanodots”。
教学情况：
承担的教学工作包括：本科生专业课《实用塑料材料学》和《功能高分子》，通识课《绿色化学与生活》，学科基础实验《有机化学实验》，创新实验《科研训练》、《综合实验》和《研究型实验》；研究生专业课《高分子材料剖析》。获聘为辽宁大学创新创业导师，辽宁大学“三师”助学育人工程导师，带领学生参加“大学生创新创业训练计划”（其中1项为国家级项目，2项为省级项目），在2015年辽宁省普通高等学校本科大学生化工设计创业竞赛中带领学生获得三等奖。