刘薇
院系：环境学院
办公电话：**
电子信箱：liu_wei@dlut.edu.cn
更新时间：2014-5-20
其他专业：无



个人简介
2008.05至今大连理工大学环境学院 讲师,副教授
2012.03至今中化集团沈阳化工研究院有限公司 安全评价中心 博士后

社会兼职
国际毒理学会会员(Society of Toxicology,SOT)
国际环境毒理和化学学会(Society of Environmental Toxicology and Chemistry, SETAC) 会员
中国毒理学会 会员


研究领域（研究课题）
在研科研项目(主持和参加)
1.典型全氟烷酸化合物的人类慢性暴露生物标志物研究。国家自然科学基金，2012.01-2014.12。
2.树叶中典型全氟烷酸化合物的富集规律、机理及环境指示作用研究。大连理工大学基本科研业务费专项项目(理科基础科研专题)，2012.1-2013.12
3.利用基因组学以人类干细胞体外检测遗传毒性效应和机制。中国博士后科学基金面上项目，2012.10-2014.3。
4.工业废水生态安全性指标体系与评价方法的构建。国家水体污染控制与治理科技重大专项子课题任务，2012.1-2015.12。
5.典型环境污染物对性别决定和性别稳定性干扰作用机制研究。国家自然科学基金面上项目，2013.1-2016.12。
6.PFOS对神经突触可塑性的影响及其机理研究。国家自然科学基金面上项目，2012.1-2014.12。
7.室内空气污染对健康影响评价技术研究。国家高技术研究发展计划(863计划)项目，2010.12-2013.12。
8.抗生素水环境光化学转化/光致毒性机理与计算模拟。国家自然科学基金重点项目，2012.1-2016.12。


硕博研究方向
(1) 持久性有机污染物暴露评估
(2) 污染物毒理效应和机理研究
(3) 化学品高通量毒性筛选技术


出版著作和论文
代表性论文
1.Mingxi Yu, Jingyun Wang, Wei Liu*, Junwen Qin, Quan Zhou, Yongan Wang, Huihui Huang, Wenli Chen, Chao Ma. Effects of tamoxifen on the sex determination gene and the activation of sex reversal in the developing gonad of mice. Toxicology 2014, 321, 89-95.
2.Fan Wang, Chonglei Li, Wei Liu*, Yihe Jin. Potential mechanisms of neurobehavioral disturbances in mice caused by sub-chronic exposure to low-dose VOCs. Inhalation Toxicology, 2014, 26(4): 250–258. IF2012=1.894
3.Wei Liu, Lei Xu, Xiao Li, Yihe Jin*, Kazuaki Sasaki, Norimitsu Saito, Itaru Sato, Shuji Tsuda. Human nails analysis as biomarker of exposure to perfluoroalkyl compounds. Environmental Science & Technology 2011, 45, 8144-8150. SCI收录, EI收录. IF2011=5.228.
4.Wei Liu, Yihe Jin*, Xie Quan, Kazuaki Sasaki, Norimitsu Saito, Shoji F. Nakayama, Itaru Sato, Shuji Tsuda. Perfluorosulfonates and perfluorocarboxylates in Snow and Rain in Dalian, China. Environment International 2009, 35(4), 737-742. SCI收录, EI收录. IF2011=5.297.
5.Wei Liu, Yaobin Zhang, Xie Quan*, Yihe Jin, Shuo Chen. Effect of per?uorooctane sulfonate on toxicity and cell uptake of other compounds with different hydrophobicity in green alga. Chemosphere 2009, 75, 405-409. SCI收录, EI收录. IF2011=3.206.
6.Wei Liu, Xiao Li, Lei Xu, Li Liu, Yihe Jin*. Influence of gestation, regular bleeding and intermittent exposure on blood perfluorooctane sulfonate levels in mice: potential factors inducing sex difference and affecting exposure evaluation. The Journal of Toxicological Sciences 2010, 35(3), 309-316. SCI收录, IF2011=1.522
7.Wei Liu, Guanghui Dong, Yihe Jin*, Kazuaki Sasaki, Norimitsu Saito, Itaru Sato, Shuji Tsuda, Shoji F. Nakayama. Occurrence of perfluoroalkyl Acids in Precipitation from Shenyang, China. Chinese Science Bulletin 2009, 54(14): 2440-2445. SCI收录, IF2011=1.321.
8.Wei Liu, Guanghui Dong, Yingwei Luo, Li Liu, Ziwei Cao, Xiaona Li, Yihe Jin*. Estimation of reference values for PFOS and PFOA in human biomonitoring and relevance of exposure among family members in China. Journal of Environmental Protection 2012, 3, 353-361.
9.Lei Xu, Wei Liu*, Yihe Jin. Perfluorooctane sulfonate and perfluorooctanoic acid in the fingernails of urban and rural children. Chinese Science Bulletin 2010, 55(33): 3755-3762. SCI收录, IF2011=1.321.
10.Faqi Wang, Wei Liu, Junsheng Ma, Mingxi Yu, Yihe Jin*, Jiayin Dai. Prenatal and neonatal exposure to perfluorooctane sulfonic acid results in changes in miRNA expression profiles and synapse associated proteins in developing rat brains. Environmental Science & Technology 2012, 46(12), 6822-6829. SCI收录, EI收录. IF2011=5.228
11.Wenjuan Zhang, Wei Liu, Jing Zhang, Huimin Zhao, Yaobin Zhang, Xie Quan, Yihe Jin*. Characterisation of acute toxicity, genotoxicity and oxidative stress posed by textile effluent on zebrafish. Journal of Environmental Sciences 2012, 24(11), 2019-2027.
12.Jia Bao, Wei Liu, Li Liu, Yihe Jin*, Jiayin Dai, Xiaorong Ran, Zhixu Zhang, Tsuda Shuji. Perfluorinated compounds in the environment and the blood of residents living near fluorochemical plants in fuxin, China. Environmental Science & Technology 2011, 45(19), 8075-8080. SCI收录, EI收录. IF2011=5.228.
13.Faqi Wang, Wei Liu, Yihe Jin*, Jiayin Dai, Hongxia Zhao, Qing Xie, Xiaohui Liu, Wenguang Yu, Junsheng Ma. Interaction of PFOS and BDE-47 Co-exposure on Thyroid Hormone Levels and TH-related Gene and Protein Expression in Developing Rat Brains. Toxicological Sciences 2011, 121(2), 279-291. SCI收录. IF2011=4.652.
14.Wenguang Yu, Wei Liu, Li Liu, Yihe Jin*. Perfluorooctane sulfonate increased hepatic expression of OAPT2 and MRP2 in rats. Archives of Toxicology 2011, 85(6), 613-621. SCI收录, IF2011=4.674.
15.Faqi Wang, Wei Liu, Yihe Jin*, Jiayin Dai, Wenguang Yu, Xiaohui Liu, Li Liu. Transcriptional Effects of Prenatal and Neonatal Exposure to PFOS in Developing Rat Brain. Environmental Science & Technology 2010, 44(5), 1847-1853. SCI收录, EI收录. IF2011=5.228.
16.Xiaohui Liu, Wei Liu, Yihe Jin*, Wenguang Yu, Faqi Wang, Li Liu. Effect of gestational and lactational exposure to perfluorooctane sulfonate (PFOS) on calcium-dependent signaling molecules gene expression in rats' hippocampus. Archives of Toxicology 2010, 84(1), 71-79. SCI收录, IF2011=4.674.
17.Xiaohui Liu, Wei Liu, Yihe Jin*, Wenguang Yu, Li Liu, Hongyao Yu. Effects of subchronic perfluorooctane sulfonate exposure of rats on calcium-dependent signaling molecules in the brain tissue. Archives of Toxicology 2010, 84(6), 471-479. SCI收录, IF2011=4.674.
18.Jia Bao, Wei Liu, Li Liu, Yihe Jin, Xiaorong Ran, Zhixu Zhang. Perfluorinated compounds in urban river sediments from Guangzhou and Shanghai of China. Chemosphere 2010, 80(2), 123-130. SCI收录, EI 收录, IF2011=3.206.
19.Wenguang Yu, Wei Liu, Yihe Jin*, Xiaohui Liu, Faqi Wang, Li Liu, Shoji Nakayama. Prenatal and postnatal impact of perfluorooctane sulfonate (PFOS) on rat development: A cross-foster study on chemical burden and thyroid hormone system. Environmental Science & Technology 2009, 43(21), 8416-8422. SCI收录, EI收录. IF2011=5.228.
20.Yihe Jin, Wei Liu, Itaru Sato, Shoji F. Nakayama, Kazuaki Sasaki, Norimitsu Saito, Shuji Tsuda. PFOS and PFOA in environmental and tap water in China. Chemosphere 2009, 77(5), 605-611. SCI收录, EI 收录, IF2011=3.206.
21.Wenguang Yu, Wei Liu, Yihe Jin*. Effects of perfluorooctane sulfonate on rat thyroid hormone biosynthesis and metabolism. Environmental Toxicology and Chemistry 2009, 28(5), 990-996. SCI收录, EI收录. IF2011=2.809.
22.Fan Wang, Chonglei Li, Wei Liu, Yihe Jin*. Oxidative damage and genotoxic effect in mice caused by sub-chronic exposure to low-dose volatile organic compounds. Inhalation Toxicology 2013, 25(5): 235-42.
23.Jing Zhang, Yaobin Zhang, Wei Liu, Xie Quan*, Shuo Chen, Huimin Zhao, Yihe Jin, Wenjuan Zhang. Evaluation of removal efficiency for acute toxicity and genotoxicity on zebrafish in anoxic-oxic process from selected municipal wastewater treatment plants. Chemosphere 2013, 90(11): 2662-2666.
24.Feng Tan, Yihe Jin, Wei Liu, Xie Quan, Jingwen Chen, Zhen Liang. Global liver proteome analysis using iTRAQ labeling quantitative proteomic technology to reveal biomarkers in mice exposed to perfluorooctane sulfonate (PFOS). Environmental Science & Technology 2012, 46(21): 12170-12177.
25.Fan Wang, Chonglei Li, Wei Liu, Yihe Jin*. Effect of exposure to volatile organic compounds (VOCs) on airway inflammatory responses in mice. The Journal of Toxicological Sciences 2012, 37(4), 739-748. SCI收录, IF2011=1.522
26.Fan Wang, Chonglei Li, Wei Liu, Yihe Jin*. Oxidative stress levels of Kunming mice following short-term exposure to volatile organic compounds (VOCs) mixture. Journal of Animal and Veterinary Advances 2012, 11 (18): 3417-3426.
27.Fan Wang, Chonglei Li, Wei Liu, Yihe Jin*. Effects of exposure to VOCs on spatial learning and memory and the expression of NMDA receptor in mice. Journal of Animal and Veterinary Advances 2012, 11 (18): 3355-3364.
28.Xiaohui Liu, Yihe Jin*, Wei Liu, Faqi Wang, Shuang Hao. Possible mechanism of perfluorooctane sulfonate and perfluorooctanoate on the release of calcium ion from calcium stores in primary cultures of rat hippocampal neurons. Toxicology in Vitro 2011, 25(7), 1294-1301. SCI收录，IF2011=2.775.
29.Jia Bao, Yihe Jin*, Wei Liu, Xiaorong Ran, Zhixu Zhang. Perfluorinated compounds in sediments from the Daliao river system of northeast China. Chemosphere 2009, 77(5), 652-657. SCI收录, EI 收录, IF2011=3.206.
30.Xiao Li, Jianqing Zhang, Wei Liu, Xiaona Li, Xin Zhang, Yousheng Jiang, Jian Zhou, Yihe Jin*. Serum levels of perfluorinated compounds in the general population in Shenzhen, China. Chinese Science Bulletin 2011,56(28-29), 3092-3099. SCI收录, IF2011=1.321.


工作成果（奖励、专利等）
论文获奖
1. 刘薇，许蕾，李笑，金一和。Human nails analysis as biomarker of exposure to perfluoroalkyl compounds。辽宁省自然科学学术成果奖，三等奖，2012.
2. 刘薇。Human nails analysis as biomarker of exposure to perfluoroalkyl compounds。大连市自然科学优秀学术论文，一等奖，2012.
3. 刘薇，金一和，全燮。大连市降水中全氟烷酸、羧酸化合物的污染水平和分布特征。辽宁省自然科学学术成果奖，三等奖，2011.
4. 刘薇。大连市降水中全氟烷酸、羧酸化合物的污染水平和分布特征。大连市自然科学优秀学术论文，一等奖，2011.
5. 金一和，刘薇。中国环境水体和自来水中PFOS和PFOA的污染水平和分布特征。辽宁省自然科学学术成果奖 二等奖，2011.
6. 王法琦，刘薇，金一和，戴家银. Interaction of PFOS and BDE-47 coexposure on thyroid hormone levels and TH-related gene and protein expression in developing rat brains. 辽宁省自然科学学术成果奖 二等奖，2012.
6. 王法琦，刘薇，金一和。出生前PFOS暴露对发育期大鼠脑基因表达的影响。辽宁省自然科学学术成果奖 三等奖，2011.
7. 刘晓晖，刘薇，金一和，于文广。Effects of subchronic perfluorooctane sulfonate exposure of rats on calcium-dependent signaling molecules in the brain tissue. 辽宁省自然科学学术成果奖，三等奖，2012.
8. 于文广，刘薇，刘利，金一和。Perfluorooctane sulfonate increased hepatic expression of OAPT2 and MRP2 in rats. 辽宁省自然科学学术成果奖，三等奖，2012.
7. 鲍佳，金一和，刘薇。Perfluorinated compounds in sediments from the Daliao River system of northeast China。辽宁省自然科学学术成果奖 三等奖，2011.

荣誉称号
1、获大连理工大学 “考核优秀”荣誉称号，2011。
2、获大连理工大学化工与环境生命学部 “优秀教师”荣誉称号，2011。