王桂兰
院系：化学学院
办公电话：**
电子信箱：glwang101@yahoo.com.cn
更新时间：2007-7-16
其他专业：无



个人简介
1979.9-1983.7:兰州大学化学系无机化学专业，本科生(理学学士)。
1983.9-1986.6：兰州大学化学系分析化学专业，硕士研究生(理学硕士)。
1986.7-1988.7：大连理工大学化工学院分析化学教研室，助教。
1988.8-1993.10：大连理工大学化工学院分析化学教研室，讲师。
1993.11-1995.10：日本东京，日语学习。
1995.11-1999.3：早稻田大学理工学综合研究中心，访问学者。
1999.4-2000.3：早稻田大学理工学综合研究中心，研究助手。
2000.4-2002.3：中国科学院大连化学物理研究所，副研究员。
2001.12：获兰州大学研究生院分析化学专业同等学力理学博士学位。
2002.4-2004.3：早稻田大学理工学部化学系，博士后。
2004.4-2006.2：中国科学院大连化学物理研究所，副研究员，硕士研究生导师。
2006.3-至今：大连理工大学化工学院分析化学教研室，教授，硕士研究生导师。

研究领域（研究课题）
生物分析化学

硕博研究方向
荧光探针合成及生化分析应用

出版著作和论文
论文：
1.Jing Wu, Zhiqiang Ye, Guilan Wang, Jingli Yuan, “Multifunctional nanoparticles possessing magnetic, long-lived fluorescence and bio-affinity properties for time-resolved fluorescence cell imaging”, Talanta, 72, 1693-1697 (2007).
2.Bo Song, Guilan Wang, Jingli Yuan, “Measurement and characterization of singlet oxygen production in copper ion-catalyzed aerobic oxidation of ascorbic acid”, Talanta, 72 (1), 231-236 (2007).
3.Bo Song, Guilan Wang, Mingqian Tan, Jingli Yuan, “A europium(III) complex as an efficient singlet oxygen luminescence probe”, J. Am. Chem. Soc. 128 (41), 13442-13450 (2006).
4.Takuya Nishioka, Jingli Yuan, Yuji Yamamoto, Keiko Sumitomo, Zhen Wang, Kimikazu Hashino, Chihiro Hosoya, Keisuke Ikawa, Guilan Wang, Kazuko Matsumoto, “New luminescent europium(III) chelates for DNA labeling”, Inorg. Chem., 45 (10), 4088-4096 (2006).
5.Mingqian Tan, Bo Song, Guilan Wang and Jingli Yuan, “A new terbium(III) chelate as an efficient singlet oxygen fluorescence probe”, Free Radic. Biol. Med., 40 (9), 1644-1653 (2006).
6.Jingli Yuan, Guilan Wang, “Lanthanide-based luminescence probes and time-resolved luminescence bioassays”, TrAC-Trends Anal. Chem. 25 (5), 490-500 (2006) (invited review).
7.Guilan Wang, Jingli Yuan, Xiaodan Hai, Kazuko Matsumoto, “Homogeneous time-resolved fluoroimmunoassay of 3,5,3’-triiodo-L-thyronine in human serum by using europium fluorescence energy transfer”, Talanta, 70 (1), 133-138 (2006).
8.Mingqian Tan, Guilan Wang, Zhiqiang Ye, Jingli Yuan, “Synthesis and characterization of titania-based monodisperse fluorescent europium nanoparticles for biolabeling”, J. Lumin. 117 (1), 20-28 (2006).
9.胡政, 靳艳, 袁景利, 王桂兰, 张卫, 邓麦村, “一种可用于天然产物粗提物的HIV-1逆转录酶抑制剂筛选方法”, 中国药理学通报, 22 (5), 639-640 (2006).
10.Bo Song, Guilan Wang, Mingqian Tan, Jingli Yuan, “Synthesis and time-resolved fluorometric application of a europium chelate-based phosphorescence probe specific for singlet oxygen”, New J. Chem., 29 (11), 1431 - 1438 (2005).
11.Bo Song, Guilan Wang, Jingli Yuan, “A new europium chelate-based phosphorescence probe specific for singlet oxygen”, Chem. Commun., 3553-3555 (2005).
12.Jingli Yuan, Guilan Wang, “Lanthanide complex-based fluorescence label for time-resolved fluorescence bioassay”, J. Fluoresc., 15 (4), 559-568 (2005) (invited review).
13.Zhiqiang Ye, Mingqian Tan, Guilan Wang, Jingli Yuan, “Preparation, characterization and application of fluorescent terbium complex-doped zirconia nanoparticles”, J. Fluoresc., 15 (4), 499-505 (2005).
14.Zhiqiang Ye, Mingqian Tan, Guilan Wang, Jingli Yuan, “Development of functionalized terbium fluorescent nanoparticles for antibody labeling and time-resolved fluoroimmunoassay application”, Talanta, 65, 206-210 (2005).
15.Mingqian Tan, Zhiqiang Ye, Guilan Wang, Jingli Yuan, “Preparation and time-resolved fluorometric application of the luminescent europium nanoparticles”, Chem. Mater., 16, 2494-2498 (2004).
16.Zhiqiang Ye, Mingqian Tan, Guilan Wang, Jingli Yuan, “Preparation, characterization and time-resolved fluorometric application of silica-coated terbium(III) fluorescent nanoparticles”, Anal. Chem., 76, 513-518 (2004).
17.Jingli Yuan, Mingqian Tan, Guilan Wang, “Synthesis and luminescence properties of lanthanide(III) chelates with polyacid derivatives of thienyl-substituted terpyridine analogues”, J. Lumin., 106, 91-101 (2004).
18.Xiaodan Hai, Mingqian Tan, Guilan Wang, Zhiqiang Ye, Jingli Yuan, Kazuko Matsumoto, “Preparation and a time-resolved fluoroimmunoassay application of new europium fluorescent nanoparticles”, Anal. Sci., 20, 245-246 (2004).
19.Zhiqiang Ye, Mingqian Tan, Guilan Wang, Jingli Yuan, “Novel fluorescent europium chelate-doped silica nanoparticles: Preparation, characterization and time-resolved fluorometric application”, J. Mater. Chem., 14 (5), 851-856 (2004).
20.Mingqian Tan, Guilan Wang, Xiaodan Hai, Zhiqiang Ye, Jingli Yuan, “Development of functionalized fluorescent europium nanoparticles for biolabeling and time-resolved fluorometric application”, J. Mater. Chem., 14, 2896-2901 (2004).
21.李德鹏, 王桂兰, 袁景利, “新型对苯二乙烯二菁荧光染料的合成”, 化学研究与应用, 16, 635-638 (2004).
22.Keisuke Majima, Takashi Fukui, Jingli Yuan, Guilan Wang, Kazuko Matsumoto, “Quantitative measurement of 17b-estradiol and estriol in river water by time-resolved fluoroimmunoassay”, Anal. Sci., 18, 869-874 (2002).
23.朱艳冰,李庆阁,王桂兰,袁景利. 新型铕络合物用于HBsAg的时间分辨荧光免疫检测,标记免疫分析与临床,9,157-160(2002).
24.Guilan Wang, Jingli Yuan, Kazuko Matsumoto, Zhide Hu, “Homogeneous time-resolved fluoroimmunoassay of bensulfuron-methyl by using terbium fluorescence energy transfer”, Talanta, 55, 1119-1125 (2001).
25.Guilan Wang, Jingli Yuan, Kazuko Matsumoto, Zhide Hu, “Homogeneous time-resolved fluorescence DNA hybridization assay by DNA-mediated formation of an EDTA-Eu(III)-beta-diketonate ternary complex”, Anal. Biochem., 299, 169-172 (2001).
26.Guilan Wang, Jingli Yuan, Benling Gong, Kazuko Matsumoto, Zhide Hu, “Immunoassay by graphite furnace atomic absorption spectrometry using a metal chelate as a label”, Anal. Chim. Acta, 448, 165-172 (2001).
27.Jingli Yuan, Guilan Wang, Kesukei Majima, Kazuko Matsumoto, “Synthesis of a new terbium fluorescent chelate and its application to time-resolved fluoroimmunoassay”, Anal. Chem. 73, 1869-1876 (2001).
28.Guilan Wang, Jingli Yuan, Kazuko Matsumoto, Hiroko Kimura, “Quantitative measurement of p21 protein in human serum by time-resolved fluoroimmunoassay”, Anal. Sci., 17, 881-883 (2001).
29.Hiroko Kimura, Masahiro Mukaida, Guilan Wang, Jingli Yuan, Kazuko Matsumoto, “Dual-label time-resolved fluoroimmunoassay of psychopharmaceuticals and stimulants in serum”, Forensic Sci. Int., 113, 345-351 (2000).
30.Kazuko Matsumoto, Jingli Yuan, Guilan Wang, Hiroko Kimura, "Simultaneous determination of a-fetoprotein and carcinoembryonic antigen in human serum by time-resolved fluoroimmunoassay", Anal. Biochem., 276, 81-87 (1999).
31.Hiroko Kimura, Jingli Yuan, Guilan Wang, Kazuko Matsumoto, Masahiro Mukaida,"Highly sensitive quantitation of methamphetamine by time-resolved fluoroimmunoassay using a new europium chelate as a label", J. Anal. Toxicol., 23, 11-16 (1999).
32.Jingli Yuan, Guilan Wang, Hiroko Kimura, Kazuko Matsumoto, "Highly sensitive detection of bensulfuron-methyl by time-resolved fluoroimmunoassay using a tetradentate beta-diketonate europium chelate as a label", Anal. Sci., 15, 125-128 (1999).
33.Jingli Yuan, Guilan Wang, Hiroko Kimura, Kazuko Matsumoto, "Sensitive time-resolved fluoroimmunoassay of human thyroid-stimulating hormone by using a new europium fluorescent chelate as a label", Anal. Sci. 14, 421-423 (1998).
34.Jingli Yuan, Guilan Wang, Hiroko Kimura, Kazuko Matsumoto, "Highly sensitive time-resolved fluoroimmunoassay of human immunoglobulin E by using a new europium fluorescent chelate as a label", Anal. Biochem., 254, 283-287 (1997).
35.Jingli Yuan, Guilan Wang, Hiroko Kimura, Kazuko Matsumoto, "Synthesis of a new tetradentate beta-diketonate europium chelate and its application for protein labeling and highly sensitive time-resolved fluoroimmunoassay", J. Inorg. Biochem., 67, 429 (1997).

专著:
1.Jingli Yuan, Guilan Wang, Kazuko Matsumoto, “Lanthanide fluorescence chelates and their application in bioassays”, Trends in Inorganic Chemistry, 7, 109-117 (2001).
2.Guoliang Zhao, Guilan Wang, Handbook of Advanced Materials Testing, Part 1, Section 5, "Ion-Exclusion Chromatography",Marcel Dekker, Inc., Edited by N. P. Cheremisinoff and P. N. Cheremisinoff, pp 65-85, 1995.


在读学生人数
硕士2人