樊江莉
院系：精细化工国家重点实验室
办公电话：**
电子信箱：fanjl@dlut.edu.cn
更新时间：2016-4-14
其他专业：★精细化工生物化工



个人简介


樊江莉，大连理工大学精细化工国家重点实验室，教授，博士生导师。国家自然科学基金优秀青年基金获得者，首届教育部“青年长江”。

社会兼职
国家自然科学基金涵审专家
Journal of American Chemical Society, Chemical Communications, RSC advances, Analytical Chemistry, Science in China Series B-Chemistry, Journal of Fluorescence, analyst, ,《应用化学》、《高等学校化学学报》等多种十余种杂志通讯审稿人



研究领域（研究课题）
荧光染料及其在生物、医学、材料方面的应用

精细化工产品合成技术

研究项目：

国家自然科学基金面上项目，2016/01-2019/12，在研，主持
国家自然科学基金优秀青年基金，2015/01-2017/12，在研，主持
辽宁省自然科学基金，2014/01-2015/12，已结题，主持
教育部新世纪优秀人才支持计划、NCET-12-0080、申报领域：化工、2013/01-2015/12、在研、主持。
国家重点基础研究计划（973计划）子课题、2013CB733702、针对代谢标志物的分子探针设计与合成、2012/01-2016/12、在研、参加。(首席科学家：华东理工大学，田禾院士)
国家自然科学基金重点项目、**、激发态释能调控与功能强化、2012/01-2016/12、在研、参加。
科技部863计划、2011AA02A105、新一代高性能五分类血细胞分析系统、2011/01-2012/12、已结题、子课题主持。
国家自然科学基金专项基金项目、**、新型染料分子的设计、合成及应用、2010/01-2013/12、结题、子课题主持。
国家自然科学基金面上项目、**、用于环境和生命体系中甲基汞荧光探针的研究、2010/01-2013/12、结题、主持。
辽宁省教育厅科学技术研究项目、LS**、生物分子检测与诊断用荧光试剂的开发与生产、2010/01-2012/12、8万、已结题、主持。
中央高校基本科研业务费专项基金、DUT10LK05、荧光探针用于痕量重金属离子检测、2010/01-2011/12、已结题、主持。
国家自然科学基金青年基金、**、PET荧光探针中的质子干扰研究、2008/01-2010/12、已结题、主持。
教育部博士点新教师基金、**、PET荧光探针中的质子干扰研究、2008/01-2010/12、已结题、主持。
高等学校科技创新工程重大项目培育基金、707016、细胞内若干重要活性物质的荧光可视化及在诊断中的应用、2008/01-2010/12、已结题、参加。
浙江闰土股份有限公司、**、染料中间体JB催化加氢技术、2010/09-2012/09、主持。
广州市海珠区正鸿商行、**、油墨用染料、2010/09-2012/09、主持。


硕博研究方向
应用化学、精细化工、生物化工：

（1）新的近红外荧光染料的开发

（2）荧光靶向无机纳米负载药物释放

（3）功能化分子影像探针的研发



出版著作和论文
近五年发表文章：

1.Jiangli Fan,* Zhichao Han, Yao Kang & Xiaojun Peng. A Two-Photon Fluorescent Probe for Lysosomal Thiols in Live Cells and Tissues, Scitific Reports, 2016, 6, 19652.
2.Jianjun Du, Zhenkuan Wang, Xiaojun Peng, and Jiangli Fan.* In Situ Colorimetric Recognition of Melamine Based on Thymine, Derivative-Functionalized Gold Nanoparticle, Ind. Eng. Chem. Res., 2015, 54, 12011?12016.
3.Jiangli Fan,* Huiying Mu, Hao Zhu, Jianjun Du, Na Jiang, Jingyun Wang, and Xiaojun Peng. Recognition of HClO in Live Cells with Separate Signals Using a Ratiometric Fluorescent Sensor with Fast Response, Ind. Eng. Chem. Res., 2015, 54 (36), 8842–8846.
4.Jiangli Fan,* Huiying Mu, Hao Zhu, Jingyun Wang, Xiaojun Peng. Light up ClO? in live cells using an aza-coumarin based ?uorescent probe with fast response and high sensitivity, Analyst, 2015, 140, 4594-4598.
5.Na Jiang, Jiangli Fan,* Feng Xu, Xiaojun Peng, Huiying Mu, JingyunWang, and Xiaoqing Xiong. Ratiometric Fluorescence Imaging of Cellular Polarity: Decrease in Mitochondrial Polarity in Cancer Cells, Angew. Chem. Int. Ed. 2015, 127, 2540-2544.
6.Benhua Wang, Jiangli Fan,* Xianwu Wang, Hao Zhu, Jingyun Wang,* Huiying Mu and Xiaojun Peng. A Nile blue based infrared fluorescent probe: imaging tumors that over-express cyclooxygenase-2, Chem. Commun., 2015, 51, 792-795.
7.Hao Zhu, Jiangli Fan,* Benhua Wang and Xiaojun Peng*. Fluorescent, MRI, and colorimetric chemical sensors for the first-row d-block metal ions, Chem. Soc. Rev. 2015, 44, 4437-4366.
8.Hao Zhu, Jiangli Fan*, Jingyun Wang, Huiying Mu, and Xiaojun Peng*. An “Enhanced PET”-Based Fluorescent Probe with Ultrasensitivity for Imaging Basal and Elesclomol-Induced HClO in Cancer Cells, J. Am. Chem. Soc. 2014, 136, 12820-1282。
9.Jiangli Fan,* Wen Sun, Zhenkuan Wang, Xiaojun Peng, Yueqing Li* and Jianfang Cao. A fluorescent probe for site I binding and sensitive discrimination of HSA from BSA, Chem. Commun., 2014, 50, 9573-9576.
10.Si Zhang, Jiangli Fan,* Zhiyong Li, Naijia Hao, Jianfang Cao, Tong Wu, Jingyun Wang* and Xiaojun Peng. A bright red fluorescent cyanine dye for live-cell nucleic acid imaging, with high photostability and a large Stokes shift, J. Mater. Chem. B, 2014, 2, 2688-2693.
11.Hao Zhu, Jiangli Fan,* Miao Li, Jianfang Cao, Jingyun Wang, and Xiaojun Peng. A “Distorted-BODIPY”-Based Fluorescent Probe for Imaging of Cellular Viscosity in Live Cells, Chem. Eur. J., 2014, 20, 4691-4696.
12.Guanghui Cheng , Jiangli Fan*, Wen Sun , Jianfang Cao , Chong Hu , and Xiaojun Peng*. A Near-infrared Fluorescent Probe for Selective Detection of HClO Based on Se-sensitized Aggregation of Heptamethine Cyanine Dye, Chem. Commun., 2014, 50 (8), 1018-1020.
13.Jiangli Fan*, Huijuan Dong, Mingming Hu, Jingyun Wang, Hua Zhang, Hao Zhu, Wen Sun, Xiaojun Peng*. Fluorescence Imaging Lysosome Changes During Cell Division and Apoptosis with a Nile Blue Based Near-infrared Emission, Chem. Commun., 2014, 50 (7), 882-884.
14.Hao Zhu, Jiangli Fan,* Shiling Zhang, Jianfang Cao, Kedong Song, Dan Ge, Huijuan Dong, Jingyun Wang, and Xiaojun Peng*a. Ratiometric Fluorescence Imaging of Lysosomal Zn2+ Release under Oxidative Stress in Neural Stem Cells, Biomater. Sci., 2014, 2 (1), 89-97.
15.Na Jiang, Jiangli Fan*, Si Zhang, Tong Wu, Jingyun Wang, Pan Gao, Junle Qu, Fan Zhou, Xiaojun Peng*. Dual Mode Monitoring Probe for Mitochondrial Viscosity in Single Cell, Sensors & Actuators: B. Chemical, 2014, 190, 685-693.
16.Hua Zhang, Jiangli Fan,* Jingyun Wang, Bairui Dou, Fan Zhou, Jianfang Cao, Junle Qu, Zhi Cao, Weijie Zhao, and Xiaojun Peng*. Fluorescence discrimination of cancer from inflammation by molecular response to COX-2 enzymes, J. Am. Chem. Soc. 2013, 135, 17469-17475.
17.Hua Zhang, Jiangli Fan,* Jingyun Wang, Shuangzhe Zhang, Bairui Dou, and Xiaojun Peng*. An Off?On COX-2-Specific Fluorescent Probe: Targeting the Golgi Apparatus of Cancer Cells, J. Am. Chem. Soc. 2013, 135, 11663-11669.
18.Na Jiang, Jiangli Fan,* Tao Liu, Jianfang Cao, Bo Qiao, Jingyun Wang, Pan Gao and Xiaojun Peng*. A near-infrared dye based on BODIPY for tracking morphology changes in mitochondria, Chem. Commun., 2013, 49, 10620-10622.
19.Guanghui Cheng, Jiangli Fan*, Wen Sun, Kun Sui, Xin Jin, Jingyun Wang and Xiaojun Peng*. A Highly Specific BODIPY-Based Probe Localized in Mitochondria for HClO Imaging, Analyst, 2013, 138, 6091-6096.
20.Huazhang, Jiangli Fan,* Huijuan Dong, Shuangzhe Zhang, Wenyou Xu, Jingyun Wang, Pan Gao and Xiaojun Peng*. Fluorene-derived two-photon fluorescent probes for specific and simultaneous bioimaging of endoplasmic reticulum and lysosomes: group-effect and localization, J. Mater. Chem. B, 2013, 1, 5450–5455.
21.Jiangli Fan, Chunying Lin, Honglin Li, Peng Zhan, Jingyun Wang, Shuang Cui, Mingming Hua, Guanghui Cheng, Xiaojun Peng*. A ratiometric lysosomal pH chemosensor based on fluorescence resonance energy transfer, Dyes and Pigments, 2013, 99, 620-626.
22.Honglin Li, Jianfang Cao, Hao Zhu, Jiangli Fan*, Xiaojun Peng*. Optical Pd2+ sensing by rhodamine hydrazone ligands: different stoichiometries in aqueous/nonaqueous environments, Tetrahedron Letters, 2013, 54, 4357–4361.
23. Maozhong Tian, Mingming Hu, Jiangli Fan*, Xiaojun Peng, Jingyun Wang, Shiguo Sun, Rong Zhang. Rhodamine-based ‘turn-on’ fluorescent probe for Cu(II) and its fluorescence imaging in living cells, Bioorganic & Medicinal Chemistry Letters, 2013, 23, 2916–2919.
24.Honglin Li, Jiangli Fan, Xiaojun Peng*. Colorimetric and Fluorescent Probes for Optical Detection of Palladium, Chem. Soc. Rev., 2013, 42, 7943-7962.
25.Wen Sun, Jiangli Fan,* Chong Hu, Jianfang Cao, Hua Zhang, Xiaoqing Xiong, Jingyun Wang, Shuang Cui, Shiguo Sun and Xiaojun Peng*. A two-photon fluorescent probe with near-infrared emission for hydrogen sulfide imaging in biosystems, Chem. Commun., 2013, 49, 3890-3892.
26.Jiangli Fan*, Peng Zhan, Mingming Hu, Wen Sun, Jizhou Tang, Jingyun Wang, Shiguo Sun, Fengling Song and Xiaojun Peng*. A fluorescent ratiometric chemodosimeter for Cu2+ based on TBET and its application in living cells, Org. Lett., 2013, 15, 492-495.
27.Jiangli Fan, Mingming Hu, Peng Zhan, Xiaojun Peng*, Energy Transfer Cassettes Based on Organic Fluorophores: Construction and Applications in Ratiometric Sensing, Chem. Soc. Rev., 2013, 42, 29-43.
28.刘飞，吴彤，胡明明，彭孝军，樊江莉*, A Novel Carbazole-based Cyanine as a Fluorescent Probe for Viscosity Detection，高等学校化学学报，2012, 33(10), 2239-2243.
29.Hao Zhu, Jiangli Fan,* Qunli Xu, Honglin Li, Jingyun Wang, Pan Gao and Xiaojun Peng*. Imaging of lysosomal pH changes with a fluorescent sensor containing a novel lysosome-locating group, Chem. Commun., 2012, 48, 11766–11768.
30.Honglin Li, Jiangli Fan*, Mingming Hu, Guanghui Cheng, Danhong Zhou, Tong Wu, Fengling Song, Shiguo Sun, Chunying Duan, Xiaojun Peng*. Highly sensitive and fast-responsive fluorescent chemosensor for palladium: reversible sensing and visible recovery, Chemistry - A European Journal, 2012, 18(39), 12242-50.
31.强新新，赵志超，宋锋玲，彭孝军，樊江莉*，超细荧光聚合物纳米微球的制备，应用化学, 2012, 29(6), 633-638.
32.吴彤，彭孝军，胡明明，刘飞，樊江莉*，一种高效灵敏的DNA 荧光探针的合成及应用，高等学校化学学报, 2012, 7, 1407-1412.
33.Jiangli Fan,* Wen Sun, Mingming Hu, Jianfang Cao, Guanghui Cheng, Huijuan Dong,Kedong Song, Yingchao Liu, Shiguo Sun and Xiaojun Peng*. An ICT-based ratiometric probe for hydrazine and its application in live cells, Chem. Commun., 2012, 48, 8117–8119.
34.Jiangli Fan*, Xiaojian Liu, Mingming Hu, Hao Zhu, Fengling Song, Xiaojun Peng*. Development of an oxidative dehydrogenation-based fluorescent probe for Cu2+ and its biological imaging in living cells, Analytica Chimica Acta, 2012, 735, 107-113.
35.Jianjun Du, Mingming Hu, Jiangli Fan* and Xiaojun Peng*. Fluorescent Chemodosimeters Using “Mild” Chemical Events for Detection of Small Anions and Cations in Biological and Environmental Media, Chem. Soc. Rev., 2012, 41, 4511-4535.
36.Mingming Hu, Jiangli Fan*, Jianfang Cao, Kedong Song, Hua Zhang, Shiguo Sun and Xiaojun Peng*. Enhanced fluorescent chemosensor for Ag+ in absolute aqueous solution and living cells: An experimental and theoretical study, Analyst, 2012, 137, 2107-2111.
37.Maozhong Tian, Xiaojun Peng, Jiangli Fan*, Jingyun Wang, Shiguo Sun, A fluorescent sensor for pH based on rhodamine fluorophore, Dyes and Pigments, 2012, 95, 112-115.
38.Hao Zhu, Jiangli Fan*, Jing Lu, Mingming Hu, Jianfang Cao, Jing Wang, Honglin Li, Xiaojian Liu, Xiaojun Peng*. Optical Cu2+ probe bearing an 8-hydroxyquinoline subunit: High sensitivity and large fluorescence enhancement, Talanta, 2012, 93, 55-61.
39.Jiangli Fan*, Xiaojun Peng, Song Wang, Xiaojian Liu, Honglin Li, Shiguo Sun. A Fluorescence turn-on Sensor for Hg2+ with a Simple Receptor Available in Sulphide-rich Environments, Journal of Fluorescence, 2012, 22, 945-951.
40.Mingming Hu, Jiangli Fan*, Honglin Li, Kedong Song, Song Wang, Guanghui Cheng and Xiaojun Peng*. Fluorescent Chemodosimeter for Cys/Hcy with a Large Absorption Shift and Imaging in Living Cells, Organic & Biomolecular Chemistry, 2011, 9(4), 980-983.
41.胡明明，樊江莉*，李宏林，帕哈丁.泽耀东， 彭孝军. 荧光探针可视化检测水溶液中铜离子，分析化学，2011, 39(8), 1195-1200.
42.樊江莉*，芦静，李宏林，刘晓健，朱浩，彭孝军. 改进的罗丹明类钯离子荧光分子探针，应用化学, 2011, 28(11), 1292-1297.
43.王嵩，李宏林，胡明明，彭孝军，樊江莉*. 甲基汞检测研究进展，化学研究与应用，2011, 23(2), 129-136.


工作成果（奖励、专利等）
荧光染料识别与响应调控的理论与应用基础研究，国家自然科学二等奖（2014年，排名第3）
染料功能强化的基础与应用研究，教育部自然科学一等奖（2012年，排名第3）；

获批专利：
1.樊江莉、王本花、彭孝军、仉华，一类以尼罗兰为母体的近红外荧光探针、其制法及应用，中国发明专利，授权公告日：2016年3月18日
2.樊江莉、朱浩、彭孝军、王静云，一类氟化硼络合二吡咯甲川荧光探针，其制备方法及应用，中国发明专利，授权公告日：2015年2月4日
3.樊江莉、董惠娟、彭孝军、胡明明，一类尼罗蓝荧光染料，其制备方法及应用，中国发明专利，授权公告日：2014年5月21日
4.樊江莉、朱浩、彭孝军、徐群利，一类罗丹明荧光染料，其制备方法及应用，中国发明专利，授权公告日：2013年11月6日
5.樊江莉、安迪鲁.李、彭孝军、强新新、王倩，一类双苄基五甲川菁荧光染料、其制备方法及应用，中国发明专利，授权公告日：2014年2月5日
6.彭孝军、樊江莉、王嵩、李宏林、胡明明、宋克东，汞离子检测用氟硼染料荧光探针，中国发明专利，授权公告日：2013年5月8日
7.彭孝军、樊江莉、杜健军、王静云、张剑洲、孙世国，一类荧光探针及其制备方法和应用，中国发明专利，授权公告日：2013年1月30日
8.彭孝军、樊江莉、李宏林、王静云、孙世国，一类荧光探针化合物及其制备方法和用途，中国发明专利，授权公告日：2012年11月14日
9.彭孝军、樊江莉、杜健军、王静云、张剑洲、孙世国，Fluorescent probe compounds, preparation method and use thereof, 美国专利，授权公告日：2014年3月4日


在读学生人数
硕士生4人
博士生4名


毕业学生人数
硕士生11人，联合培养博士生5人