陈京怡,
林洪丽^,,
杨宁
大连医科大学附属第一医院 肾内科, 辽宁 大连 116011

基金项目: 辽宁省自然科学基金项目（20170540269）


详细信息 作者简介: 陈京怡(1993-), 女, 住院医师。E-mail: 287108653@qq.com



通讯作者: 林洪丽, 主任医师。E-mail: linhongli@vip.163.com 中图分类号: R692.5


摘要:透析时机是影响终末期肾脏病患者预后的独立危险因素，但目前关于终末期肾脏病患者的透析时机尚无定论。国内外研究以eGFR或Ccr界定早晚透析，但其与终末期肾脏病患者临床结局的关系结论不一。目前指南推荐的透析时机为eGFR或Ccr结合临床症状或体征。因诸多因素影响透析时机，所以需要进一步探索应用多因素评价透析时机的定量方法，开展更多随机对照研究以提供高质量的证据，为终末期肾脏病患者确定更适宜的透析时机。
关键词: 透析时机/
终末期肾脏病/
临床结局/
评价方法


Abstract:Dialysis timing is an independent risk factor for ESRD patients. However, there is no consistent conclusion about dialysis timing. Studies have been using eGFR or Ccr to define early and late dialysis, but there are different conclusions on the relationship between dialysis timing and the clinical outcome for ESRD patients. Current guidelines suggest eGFR or Ccr combined with clinical symptoms or signs. Dialysis timing is affected by many factors. Therefore, it is necessary to further explore quantitative methods using multiple factors to evaluate dialysis timing and develop more randomized controlled trials to provide high-quality evidence to determine more appropriate dialysis timing for ESRD patients.
Keywords:dialysis timing/
ESRD/
clinical outcome/
evaluation methods

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https://journal.dmu.edu.cn/data/article/export-pdf?id=dlykdxxb_20210115