庞梦端,
张洪峰^,
大连医科大学附属第一医院 风湿免疫科, 辽宁 大连 116011

基金项目: 国家"十三五"重点研发计划精准医学研究专项（2017YFC0907604）


详细信息 作者简介: 庞梦端(1990-), 女, 主治医师。E-mail:1051317999@qq.com


通讯作者: 张洪峰, 教授。E-mail:Zhf20160727@163.com 中图分类号: R593.22


摘要:目的调查类风湿关节炎（RA）患者的疼痛状况并分析相关因素。方法共收集了625例类风湿关节炎（rheumatoid arthritis，RA）患者，视觉模拟评分（VAS）评估患者疼痛程度，以VAS平均值分为两组（VAS < 43.8组与VAS≥43.8组），分析疼痛的相关危险因素。再选取关节压痛和肿胀均为阴性的患者共143例，分为VAS < 20组和VAS≥20两组，分析疼痛的相关危险因素。结果625例RA患者中VAS≥20者比例高达70%，疼痛危险因素包括男性、晨僵时间、肿胀关节数、压痛关节数、PLT、ESR、NSAIDs应用率。在关节压痛和肿胀均为阴性的患者中仍有23%的患者VAS超过20，但未得出疼痛的相关危险因素。结论疼痛是RA患者严重的临床症状，疾病活动度不是唯一导致疼痛的因素。
关键词: 类风湿关节炎/
疼痛/
视觉模拟评分


Abstract:ObjectiveTo investigate pain prevalence in patients with rheumatoid arthritis (RA), and to analyze pain-related risk factors.MethodsTotally, 625 patients with RA were recruited. Visual analog scale (VAS) was applied for pain assessment. Patients were divided into two groups according to the average VAS score of 43.8, and independent predictors of pain were analyzed. The 143 patients without joint swelling or joint pain were further divided into two groups according to VAS score of 20, and independent predictors of pain were analyzed.ResultsAmong the 625 RA patients, the proportion of patients with VAS≥20 was as high as 70%. Independent predictors of pain included male, morning stiffness time, swollen joint count, tender joint count, ESR, PLT and the usage rate of NSAIDs. Among the 143 RA patients without joint swelling or joint pain, the proportion of patients with VAS≥20 was 23%. However, no risk factors were detected.ConclusionPain is a serious clinical symptom in RA patients. Disease activity is not the only risk factor of pain.
Keywords:rheumatoid arthritis/
pain/
visual analog scale

PDF全文下载地址:

https://journal.dmu.edu.cn/data/article/export-pdf?id=dlykdxxb_20200213