李银萌^1,,
严滨^2,,
1. 大连市妇女儿童医疗中心 妇产科, 辽宁 大连 116037
2. 大连医科大学附属第一医院 妇产科, 辽宁 大连 116011

详细信息 作者简介: 李银萌(1994-), 女, 住院医师。E-mail:824337878@qq.com


通讯作者: 严滨, 教授。E-mail:yanbin6510@163.com 中图分类号: R714.259


摘要:目的分析子痫前期患者的临床资料和血常规、肝肾功能、血脂等检验指标的变化。方法收集2014年10月至2018年1月在大连医科大学附属第一医院住院的382例孕妇的临床资料及检验结果，将所有孕妇分为子痫前期重度组（n=148）、子痫前期轻度组（n=84）、正常妊娠组（n=150），分析各组孕前BMI、血常规、生化检验中部分化验结果及妊娠结局。结果子痫前期重度组、轻度组孕前BMI，HB值、CysC、UA较正常对照组明显增高，组间比较差异有统计学意义（P < 0.05）。子痫前期重度组及子痫前期轻度组TG值均高于正常组，差异有统计学意义（P < 0.05）；三组的Hcy值均在正常范围内，以子痫前期重度组值为最高，子痫前期重度组分别与子痫前期轻度组、正常妊娠组相比，差异有统计学意义（P < 0.05）。子痫前期重度组的孕龄及胎儿体重均低于正常组，差异有统计学意义（P < 0.05）。结论子痫前期的发生发展与孕前BMI、HB、CysC、UA、TG、Hcy有关。
关键词: 子痫前期/
胱抑素C/
尿酸/
同型半胱氨酸


Abstract:ObjectiveTo analyze the clinical data of patients with preeclampsia (PE) and index changes of routine blood, renal function and serum lipid in order to investigate the related pathogenic factors of PE.MethodsThe pregnant women were grouped based on clinical data and test results. The general data, blood routine, biochemical test and pregnancy outcome of the three groups were compared.ResultsThe prepregnancy BMI, HB, CysC and UA in severe and mild preeclampsia groups were significantly higher than those in normal control group (P < 0.05). The TG and Hcy values in preeclampsia group were significantly higher than those in normal control group (P < 0.05). Gestational age and fetal weight in severe mild preeclampsia group were significantly lower than those in normal control group (P < 0.05).ConclusionThe occurrence and development of preeclampsia is associated with changes in prepregnancy BMI, HB, CysC, UA, TG, Hcy.
Keywords:preeclampsia/
cystatin C/
uric acid/
homocysteine

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https://journal.dmu.edu.cn/data/article/export-pdf?id=dlykdxxb_20200312