纪红景,
商宇红^,
大连医科大学附属第一医院 妇产科, 辽宁 大连 116011

基金项目: 大连市科技创新项目（2020JJ27SN097）；大连市医学科学研究计划（1912002）


详细信息 作者简介: 纪红景(1989-), 女, 副主任医师。E-mail:jihongjing@yeah.net


通讯作者: 商宇红, 主任医师。研究方向:妇科肿瘤及妇科微创治疗。E-mail:shangyuhong@dmu.edu.cn 中图分类号: R737.33


摘要:子宫内膜异位症（内异症）是妇产科常见病，给育龄期妇女的生活和工作造成严重影响。内异症恶变作为内异症的严重并发症，近年来发病呈上升趋势，但是其发病机制及与妇科恶性肿瘤的相关性尚有待探讨。本文就内异症的发病机制，内异症与妇科恶性肿瘤、特别是与卵巢癌的相关性，内异症相关性卵巢癌的起源，内异症相关性卵巢癌的信号通路等相关问题进行归纳总结，以期更好地了解内异症恶变。
关键词: 子宫内膜异位症/
子宫内膜异位症恶变/
妇科肿瘤/
子宫内膜异位症相关性卵巢癌/
发病机制/
信号通路


Abstract:Endometriosis is a common disease in obstetrics and gynecology, which has a serious impact on the life and work of women at childbearing age. As a serious complication, the incidence of malignant transformation of endometriosis has been on the rise in recent years, but its pathogenesis and its correlation with gynecological malignant tumors remains to be explored. The pathogenesis of endometriosis, the correlation between endometriosis and gynecological malignant tumors, especially ovarian carcinoma, the origin of endometriosis related ovarian carcinoma, the signaling pathway of endometriosis related ovarian carcinoma and other related issues were summarized in this paper, in order to better understand the malignant transformation of endometriosis.
Keywords:endometriosis/
malignant transformation of endometriosis/
gynecological tumors/
endometriosis associated ovarian carcinoma/
pathogenesis/
signaling pathways

PDF全文下载地址:

https://journal.dmu.edu.cn/data/article/export-pdf?id=dlykdxxb_20200501