朱旭,
马翼,
潘昌杰^,
南京医科大学附属常州市第二人民医院 放射科, 江苏 常州 213100

详细信息 作者简介: 朱旭(1993-), 男, 住院医师。E-mail: 2223954432@qq.com



通讯作者: 潘昌杰, 教授。E-mail: panchangjie@njmu.edu.cn 中图分类号: R44


摘要:目的探讨前列腺组织良恶性病变的T₂ mapping与T₂^* mapping定量值的差异，为前列腺良恶性病变的诊断与鉴别诊断提供依据。方法收集50例前列腺病变患者的临床资料，其中前列腺癌19例，良性前列腺病变31例，均具有手术病理或超声引导下穿刺活检病理。通过常规MRI检查及T₂ mapping与T₂^* mapping检查，测量良恶性病灶的T₂ mapping与T₂^* mapping定量值，分析两者之间的差异，绘制ROC曲线，确定最佳诊断临界值及其敏感性和特异性，评价诊断效能。结果前列腺良恶性病变的T₂ mapping与T₂^* mapping定量值差异具有统计学意义（P < 0.01），其中良恶性病变的T₂ mapping与T₂^* mapping定量值分别为（93.15±11.17）ms vs（43.21±15.39）ms和（74.50±6.93）ms vs（21.53±6.81）ms；T₂mapping和T₂^* mapping定量值诊断的敏感性和特异性，最佳截断值，AUC，分别为68.4% vs 94.7%，96.8% vs 74.2%，77.49 ms vs 31.66 ms，0.91 vs 0.88。结论T₂ mapping与T₂^* mapping定量值有助于辨别前列腺良恶性的病变，是前列腺磁共振检查序列的良好补充。
关键词: T₂ mapping/
T₂^* mapping/
前列腺癌


Abstract:ObjectiveTo investigate the difference between quantitative values of T₂ mapping and T₂^* mapping in benign and malignant lesions of prostate, in order to provide a basis for diagnosis and differential diagnosis of benign and malignant prostate lesions.MethodsA total of 50 cases were studied, including 19 cases of prostate cancer and 31 cases of benign prostate lesions, all of which had surgical pathology or ultrasound-guided needle biopsy pathology. Routine MRI, T₂ mapping and T₂^* mapping were performed for all patients.The quantitative values of T₂ mapping and T₂^* mapping of benign and malignant lesions were measured and analyzed.The optimal diagnostic threshold, and its sensitivity and specificity were evaluated through ROC curve.ResultsThere was significant difference between T₂ mapping and T₂^* mapping in benign and malignant prostatic lesions(P < 0.01).The quantitative values of T₂ mapping and T₂^* mapping in benign and malignant lesions were(93.15±11.17)ms vs (43.21±15.39)ms and (74.50±6.93)ms vs (21.53±6.81)ms, respectively. The best cut-off values for the quantitative values of T₂mapping and T₂^* mapping, AUC, diagnostic sensitivity and specificity were 77.49 ms vs 31.66 ms, 0.91 vs 0.88, 68.4% vs 94.7% and 96.8% vs 74.2%, respectively.ConclusionThe quantitative values of T₂ mapping and T₂^* mappingare helpful to distinguish benign and malignant prostate lesions, and are good supplement to prostate MRI sequence.
Keywords:T₂ mapping/
T₂^* mapping/
prostate cancer

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