李岩，医学博士，生物学博士后，教授，博士研究生导师，校“英才工程”优秀人才，肿瘤中心合作PI。2015年起担任学校国际交流合作处副处长，主持工作。2009年博士毕业后继续博士后研究工作至2012年。加盟学校引进团队肿瘤干细胞研究院担任合作PI独立开展科研工作。与美国宾夕法尼亚大学、上海交大及中科院协和研究所开展了多项合作。
（2）研究方向
分子肿瘤学肿瘤发生及转移机制方面的研究。
（3）在研项目
1.主持：国家自然基金青年基金项目S100A4表达调节对人皮肤鳞癌与胃癌侵袭能力的影响（**）资助金额22万.
2.主持辽宁省优秀人才支持项目（LJQ**）资助金额6万
3.第二完成人：国家自然基金面上项目 长非编码RNA elRNA-7在乳腺癌转移中的作用及调控机制研究（**）资助金额：70万元
4.大连医科大学“英才工程”优秀人才，资助金额：30万元
（4）代表文章
1. Sunbin Ling, Lei Song, Ning Fan, Tingting Feng, Lu liu, Xu Yang,Mingjie Wang, Yanling Li,Yu Tian, Feng Zhao, Xiaoyu Liu,Qihong Huang, Zhaoyuan Hou, Fei Xu, Lei Shi, Yan Li*,Combination of Metformin and Sorafenib Suppresses the Growth of Hepatocellular Carcinoma Cells via Targeting the mTORC1/mTORC2 Feedback Loop.Int J Oncol 2017,50:297-309. IF2016:3.079
2. Nianzhu Zhang, Lu Liu, Ning Fan, Qian Zhang, Weijie Wang, Mingnan Zheng,Lingfei Ma*, Yan Li*, Lei Shi*. The requirement of SEPT2 and SEPT7 for migration and invasion inhuman breast cancer via MEK/ERK activation. Oncotarget, 2016 Sep 20; 7(38):61587-600 IF2016:5.168通讯
3. Kiranmai Gumireddy, Anping Li, Andrew V. Kossenkov, Masayuki Sakurai, Jinchun Yan, Yan Li, Hua Xu, Jian Wang, Paul J. Zhang, Lin Zhang, Louise C. Showe, Kazuko Nishikura, Qihong Huang. The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis. Nat Commun. Published online 2016 Feb 12. IF2016:12.124.
4. Zhao YW, Jing ZL, Li Y*, Mao WF*. Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis. Oncology Reports2016,36:567-572. IF2016:2.662(通讯作者)
5. Li L, XuN, FanN, Meng QC, Luo WC, Lv LJ, Wei Ma, Liu XY, Liu L,Xu F, Wang HX, Mao WF*, Li Y*,Upregulated KLK10 inhibits esophageal cancer proliferation and enhances cisplatin sensitivity in vitro. Oncology Reports 2015,34:2325-2332. IF2015:2.486(通讯作者)
6. Che Y, Jin S, Shi C, Wang L, Zhang X, Li Y,Baek JH. Treatment of Benign Thyroid Nodules: Comparison of Surgery with Radiofrequency Ablation. AJNR Am J Neuroradiol.2015 Jul;36(7):1321-5.IF:3.124
7. Ma W, Xiao GG, Mao J, Lu Y, Song B, Wang L, Fan S, Fan P, Hou Z, Li J, Yu X, Wang B, Wang H, Xu F, Li Y, Liu Q, Li L. Dysregulation of the miR-34a-SIRT1 axis inhibits breast cancer stemness. Oncotarget, 2015 Apr 30;6(12):10432-44. IF2015:5.008
8. Tingting Feng#, Lei Li#, Sunbin Ling, Ning Fan, Meiyu Fang,Haiquan Zhang,Xin Fang, Wen Lan，Zhaoyuan Hou, QingChun Meng, Di Jin, Fei Xu, Yan Li*. Metformin enhances radiation response of ECa109 cells through activation of ATM and AMPKBiomedicine and Pharmacotherapy. 2015,69:260-266 IF:2.326
9. Yu LJ#, Li Y#, Li C, Li H, Wu ML, Liu ZL,Kong QY, Chen XY, Liu XY, An LJ and Liu J. Restoration of S100A4 expression enhances invasive and metastatic potensials of COLO16 cutaneous squamous cancer cells. Cancer Biomarkers,2014,14,325-333 IF2014:1.721(一作)
10. Sunbin Ling, Tingting Feng, Hongqing Ke, Ning Fan, Lei Li, Zhongxing Li, Chengyong Dong, Cong Wang, Fei Xu, Li Y*, Liming Wang*. Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines Oncology Reports, 2014, 31:2611-2618. IF2014:2.301(通讯作者)
11. Sunbin Ling, Yu Tian, Haiquan Zhang, Kaiqi Jia, Tingting Feng, Deguang Sun, Zhenming Gao, Fei Xu, Zhaoyuan Hou, Li Y*, Wang LM* Metformin reverses multidrug resistance in human hepatocellular carcinoma BEL-7402/5-Fu cells. Molecular Medicine Reports, 2014, 10:2891-2897. IF2014:1.554(通讯作者)
12. Ling SB, Feng TT, Jia KQ, Tian Y, Li Y*. Inflammation to Cancer, the Molecular Biology in Pancreas (Review). Oncology letters, 2014,7:1747-1754. IF2014:1.554(通讯作者)
13. Chen NN#, Li Y#, Liu ZL, Fu YS, Kong QY, Chen XY, Li H, Liu J.CRABP-II-and FABP5-independent-all Transretinoic acid resistance in COLO 16 human cutaneous squamous cancer cells Exp Dermatol. 2012, 21:13-8. IF:4.115
14. Li Y, Liu Zhi-Li, Zhang Kai-Li, Chen Xiao-Yan, Kong Qing-You, Wu Mo-Li, Liu Jia and Li Hong. Methylation-associated silencing of S100A4 expression in human epidermal cancers. Exp Dermatol. 18:842-8, 2009. IF:3.239
15. Li Y, Zhang KL, Sun Y, Yang Y, Chen XY,Kong QY, Wu ML, Liu J, Li H Frequent S100A4 Expression with Unique Splicing Pattern in Gastric Cancers: A hypomethylation event paralleled with E-cadherin reduction and Wnt activation.Translational Oncol 2008,4:165-76. IF:3.393.
（5） 招生专业
人体解剖学与组织胚胎学
（6）联系方式 **；**； ly316@126.com