天然药物化学
Natural Pharmaceutical Chemistry

　
徐 青 (Qing Xu)
副研究员 博士
( Associate Professor, Ph. D.)
电话：+86-**
传真：+86-**
Email: xuqing@dicp.ac.cn
　
1971年生于浙江省慈溪市，2004年毕业于大连化物所分析化学专业，获博士学位。2002年任药物化学组代组长，2003年被破格晋升为副研究员，现任组分中药组副组长。现负责中科院重要方向性项目“基于现代理论和技术的复方中药系统研究”中的“标准组分大规模制备及标准组分库的构建”课题，参加国家自然科学基金重点项目“中药药效组分的指纹图谱的分析方法研究”。主要从事液相色谱分析方法、中药指纹图谱、中药标准组分分离与表征的研究。已发表正式论文30余篇。
主要研究方向:
针对中药现代化所存在的问题，结合相关学科发展前沿，开展分析化学和中药化学新方法新技术研究。
1. 高效液相色谱及其联用技术，包括多柱色谱系统和智能优化方法，如HPLC-MSn、UPLC等方法发展；
2. 中药活指纹图谱质量控制方法；
3.组分中药高通量分离新方法、新型分离材料研究，利用分离工厂Prep-HPLC-UV-MS进行标准组分和新化合物的分离纯化。
4. 组分中药开发，包括组分配伍规律的研究。
Dr. Qing Xu born in Cixi county, Zhejiang province in 1971. He earned his Ph.D. degree (Analytical Chemistry) in Dalian Institute of Chemical Physics, CAS in 2004. He had been the representative head of Medicine Chemistry Group since Oct. 2002, and appointed Associate Professor by Dalian Institute of Chemical Physics in May 2003. Now, he is undertaking a key project from CAS about separating the standard components of TCM and building corresponding library. Meanwhile, he is participating a key project of national foundation of natural science about research on methods of chromatographic fingerprinting analysis of active components in herbal medicine.Over 30 papers have been published.
　
代表性文章 REPRESENTATIVE PUBLICATIONS
1.

Qing Xu, Feifang Zhang, Hongbin Xiao, Xinmiao Liang, Antonius Kettrup. Study on detoxification of main alkaloids in Aconitum by high performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. Frensenius Environmental Bulletin, 2005, 14(3): 194-198.
2.

Xu Qing, Wang Longxing, Zhang Xi, Jin Gaowa, Xiao Hongbin, Liang Ximiao. Method Development in HPLC Analysis for Ethyl Acetate Extract of Astragalus. Chinese Journal of Chromatography, In Press.
3.

Shisheng Wang, Qing Xu, Hongbin Xiao, et al. Iridoid glycosides from Swertia franchetiana. Phytochemistry, In Press.
4.

Xiaozhe Zhang, Xinmiao Liang, Hongbin Xiao, and Qing Xu. Direct characterization of bitter acids in a crude hop extract by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. Journal of the American Society for Mass Spectrometry, 2004, 15(2): 180-187.
5.Xiaozhe Zhang, Qing Xu, Hongbin Xiao, Xinmiao Liang. Iridoid glucosides from Stychnos nux –vomica. Phytochemistry, 2003, 64 (8): 1341-1344.