摘要： 目的 探讨间歇性气压治疗（IPC）联合仿生物电治疗（NMES）预防人工髋关节置换术后下肢深静脉血栓形成（DVT）的疗效。方法 选择接受人工髋关节置换术的126例患者为研究对象，根据术后下肢DVT预防措施分为NMES+IPC组（41例）、NMES组（43例）和IPC组（42例）。比较3组凝血指标、血液流变学指标、血流情况以及DVT发生率。结果 NMES+IPC组术后凝血酶原时间（PT）、活化部分凝血酶原时间（APTT）和股静脉血流速度明显高于NMES组和IPC组（P < 0.05），D-二聚体水平、红细胞沉降率、红细胞压积、纤维蛋白原水平、DVT发生率明显低于NMES组和IPC组（P < 0.05）。结论 人工髋关节置换术患者接受NMES联合IPC治疗，有利于提高下肢血流速度，改善全身凝血和血液流变学指标，明显降低DVT发生率。

间歇性气压治疗联合仿生物电治疗预防人工髋关节置换术后深静脉血栓形成的疗效

马爽, 王驰, 崔岩

中国医科大学附属第四医院神经外科, 沈阳 110032

收稿日期:2022-09-13出版日期:2023-04-30发布日期:2023-04-15
通讯作者:马爽E-mail:249444316@qq.com
作者简介:马爽(1984-),女,主管护师,硕士.
基金资助:辽宁省科学技术计划（2019-MS-391）；中国医科大学护理学院科研立项课题（2017HL-23）


关键词: 人工髋关节置换术, 间歇性气压治疗, 仿生物电治疗, 深静脉血栓
Abstract: Objective To investigate the clinical effect of intermittent pneumatic compression (IPC) combined with neuromuscular electrical stimulation (NMES) on the prevention of lower extremity deep vein thrombosis (DVT) after hip arthroplasty. Methods Overall, 126 patients who underwent hip arthroplasty were divided into the NMES+IPC group (n=41), NMES group (n=43), and IPC group (n=42) according to the postoperative preventive measures used. The coagulation indices, hemorheological indices, blood flow, and incidence of DVT in the three groups were compared. Results Compared with the NMES and IPC groups, the postoperative prothrombin time, active partial prothrombin time, and femoral vein blood flow velocity were significantly higher in NMES+IPC group. Furthermore, the levels of D-dimer and fibrinogen, erythrocyte sedimentation rate, hematocrit, and the incidence of DVT were significantly lower in the NMES+IPC group than in the other groups (P < 0.05). Conclusion NMES combined with IPC can increase the blood flow velocity in the lower limb, improve coagulation and hemorheological indices, and significantly reduce the incidence of DVT.
Key words: hip arthroplasty, intermittent pneumatic compression, neuromuscular electrical stimulation, deep vein thrombosis
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