摘要： RNA甲基化近年来受到越来越多的关注，甲基化能够从多方面影响RNA代谢。RNA甲基化在肿瘤及非肿瘤领域的相关研究促进了疾病的发病机制、诊断和治疗方面的进展。最近的研究发现，RNA甲基化在非肿瘤肾脏疾病中发挥关键作用，本文就mRNA甲基化在非肿瘤肾脏疾病中的作用进行综述。

RNA甲基化在非肿瘤肾脏疾病中的研究进展

冯子轩, 栾军军, 周华

中国医科大学附属盛京医院肾内科, 沈阳 110004

收稿日期:2021-10-29出版日期:2023-03-30发布日期:2023-03-21
通讯作者:周华E-mail:huazhou_cmu@163.com
作者简介:冯子轩(1996-),男,硕士研究生.
基金资助:国家自然科学基金（82170740，81770698）；辽宁省重点研发指导计划（2019JH8/10300009）


关键词: RNA甲基化, m⁶A, m⁵C, 非肿瘤肾脏疾病
Abstract: RNA methylation has received an increasing amount of attention in recent years. Methylation affects RNA metabolism in many ways，and RNA methylation plays an important role in tumors. Similarly，research on methylation in non-tumor fields has provided new insights into the pathogenesis of diseases and facilitated advances in their diagnosis and treatment. Recent studies have found that RNA methylation plays a key role in kidney diseases. This article reviews the role of mRNA methylation in kidney diseases.
Key words: RNA methylation, m⁶A, m⁵C, kidney diseases in nephrology
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