摘要： 目的 分析成年男性勃起功能障碍（ED）病情进展的相关危险因素。方法 选择2019年1月至2021年1月在南方医院就诊的成年男性ED患者114例，根据诊断分为轻度ED组（74例）和中重度ED组（40例），对比2组的年龄、体质量指数、生活习惯、心理状态、教育水平、基础疾病，对可能导致ED进展的相关危险因素进行单因素和多因素logistic回归分析。结果 单因素分析结果显示，患者的月收入水平、焦虑抑郁的心理状态、手淫的频率、阻塞性睡眠呼吸暂停综合征（OSAS）、焦虑自评量表（SAS）和抑郁自评量表（SDS）的评分对ED病情的进展有显著影响（P < 0.05）。多因素logistic回归分析结果显示，手淫频率（OR=1.108，P=0.047）和OSAS情况（OR=3.194，P=0.015）是ED病情进展的独立危险因素。结论 过度手淫、OSAS为ED由轻度向中重度进展的独立危险因素，应引起足够重视。

成年男性勃起功能障碍病情进展相关危险因素分析

贺炳麟, 范钧泓, 高广黔, 韦安阳

南方医科大学南方医院泌尿外科, 广州 510515

收稿日期:2021-03-29出版日期:2021-10-30发布日期:2021-10-11
通讯作者:韦安阳E-mail:profway@126.com
作者简介:贺炳麟(1993-),男,硕士研究生.
基金资助:国家自然科学基金（81571433）；广东省自然科学基金（2018A030313638，2020A1515010114）


关键词: 男性, 勃起功能障碍, 阻塞性睡眠呼吸暂停综合征, 危险因素
Abstract: Objective To analyze the risk factors related to the progression of erectile dysfunction (ED) in adult men. Methods One hundred and fourteen adult male patients with ED, aged 19 to 84 years old, were analyzed in Nanfang Hospital from January 2019 to January 2021. Among them, 74 cases were diagnosed as mild ED;and 40 as moderate and severe ED. Age, body mass index, living habits, mental health status, education level, and comorbidities were compared between the two groups. Univariate and multivariate logistic regression analysis was used to analyze the risk factors that may lead to the progression of ED. Results Univariate analysis showed that monthly income, symptoms of anxiety and depression, frequency of masturbation, and obstructive sleep apnea syndrome (OSAS) had significant effects on the progression of ED. Multivariate logistic regression analysis showed that masturbation frequency (OR=1.108, P=0.047) and OSAS (OR=3.194, P=0.015) were independent risk factors for the progression of ED. Conclusion Excessive masturbation and OSAS are risk factors for the progression of ED from mild to moderate or severe. Therefore, detailed history should be obtained to recognize these risk factors in patients presenting with ED.
Key words: male, erectile dysfunction, obstructive sleep apnea syndrome, risk factors
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