间充质干细胞外泌体调控血管生成机制的研究进展
马元, 庄雪莹, 陈旭中国医科大学口腔医学院·附属口腔医院儿童口腔科, 辽宁省口腔疾病重点实验室, 沈阳 110002
收稿日期:
2020-09-15出版日期:
2021-10-30发布日期:
2021-10-11通讯作者:
陈旭E-mail:chenxu@cmu.edu.cn作者简介:
马元(1996-),男,硕士研究生.基金资助:
国家自然科学基金(82071100)关键词: 间充质干细胞, 外泌体, 血管生成
Abstract: Mesenchymal stem cells (MSCs) have the unique ability to self-renew and undergo multi-lineage differentiation;they play a key role in promoting angiogenesis and repairing damaged tissues. Paracrine signaling is a key regulator of these roles of MSCs. Exosomes are extracellular vesicles secreted by eukaryotic cells that are vital for the paracrine activity of MSCs. In this paper, we reviewed the mechanisms underlying the regulation of angiogenesis by MSC-derived exosomes.
Key words: mesenchymal stem cells, exosome, angiogenesis
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