摘要： 目的 探讨超声极速成像技术所测量的中国北方成年人颈动脉血管壁弹性与体脂肪含量及分布的相关性。方法 对304例40岁以上居民进行流行病调查，统计体质量、身高、臀围（HC）、腰围（WC）及相关生化指标，计算体质量指数（BMI）及腰臀比（WHR）。采用双能X线吸收法获得体脂百分比（BFP）。应用超声极速成像技术测量颈动脉脉搏波传导速度（PWV） ，包括收缩期起始时PWV （PWVBS）以及收缩期结束时PWV （PWVES）。结果 女性及男性非肥胖组与肥胖组PWVBS与PWVES比较差异无统计学意义（P>0.05）。男性组BFP、BMI及WC与PWVBS呈正相关。女性组WC及WHR与PWVBS呈正相关；BFP及WC与PWVES呈正相关。男性BFP是PWVBS升高的独立危险因素。WC作为独立危险因素，可以导致女性PWVBS及PWVES升高。结论 中国北方成年人颈动脉血管壁弹性降低的危险因素男性为脂肪含量增高，女性为腹型肥胖。

中国北方社区人群体脂情况对颈动脉血管壁弹性的影响

刘皇亮¹, 杨军¹, 杨茹¹, 孙彤^2,3, 吕沐天², 单忠艳⁴

1. 中国医科大学附属第一医院心血管超声科, 沈阳 110001;
2. 中国医科大学附属第一医院核医学科, 沈阳 110001;
3. 中国医科大学附属盛京医院核医学科, 沈阳 110004;
4. 中国医科大学附属第一医院内分泌与代谢病科, 沈阳 110001

收稿日期:2021-01-15出版日期:2021-06-30发布日期:2021-05-28
通讯作者:杨军E-mail:junyang63@sina.com
作者简介:刘皇亮(1989-),男,医师,硕士.
基金资助:“十一五”国家科技支撑计划（2009BAI80B00）；辽宁省高等学校重大科技平台基金（16010）


关键词: 超声极速成像技术, 脉搏波传导速度, 颈动脉弹性, 腹型肥胖, 体脂百分比
Abstract: Objective To analyze the correlation between carotid artery elasticity measured using the ultrafast imaging technique and fat content and distribution in northern Chinese adults. Methods A total of 304 residents aged 40 years or above were epidemiologically investigated. Clinical characteristics including weight,height,hip circumference(HC),waist circumference(WC),and related biochemical indexes were obtained. Body mass index(BMI) and waist-to-hip-ratio(WHR) were calculated. Body fat percentage(BFP) was measured by dual energy X-ray absorption. Carotid artery pulse wave velocity(PWV) was measured by the ultrafast imaging technique,including the PWV at the beginning(PWVBS) and the end(PWVES) of the systole. Results In both males and females,there was no statistically significant difference in PWVBS and PWVES between the obese and non-obese groups(P>0.05). In the male group,BFP,BMI,and WC were positively correlated with PWVBS. In the female group,WC and WHR were positively correlated with PWVBS,while BFP and WC were positively correlated with PWVES. In the male group,BFP was an independent risk factor for increased PWVBS. In the female group,WC as an independent risk factor could lead to an increase PWVBS and PWVES. Conclusion Regarding the risk factors of reduced carotid artery elasticity in northern Chinese adults,higher fat content in males and abdominal obesity in females are the main factors.
Key words: ultrafast imaging technique, pulse wave velocity, carotid artery elasticity, abdominal obesity, body fat percentage
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