摘要： 目的 探讨维持性血液透析（MHD）患者透析后疲劳的影响因素。方法 随机抽取中国医科大学附属盛京医院第二血液透析中心MHD患者75例作为研究对象，采用修改版Piper疲乏量表（RPFS）评估患者疲劳严重程度，记录透析后恢复时间。根据RPFS评分三分位数将患者分为3组：1组（RPFS总分<2分）、2组（RPFS总分2~<6.5分）、3组（RPFS总分≥6.5分）。比较3组患者基本临床资料、睡眠质量以及透析前后检验指标。采用有序logistics回归法分析MHD患者透析后疲劳的影响因素。结果 问卷有效回收70份，患者疲劳的发生率为78.57%。3组患者透析后恢复时间、透析间期体质量增加百分比、超滤量、透析后平均动脉压以及睡眠质量差异有统计学意义（均P < 0.05）。有序logistic回归分析显示，超滤量（P=0.001）、睡眠质量（P=0.01）和透析后平均动脉压（P=0.029）与透析后疲劳有关。结论 MHD患者普遍存在透析后疲劳，超滤量高、透析后平均动脉压低和睡眠质量差是透析后疲劳的危险因素。

维持性血液透析患者透析后疲劳的影响因素分析

曾维玲, 栾中佼, 吴私, 赵自霞, 周光宇, 李德天

中国医科大学附属盛京医院肾内科, 沈阳 110004

收稿日期:2019-08-29出版日期:2020-10-30发布日期:2020-10-13
通讯作者:周光宇E-mail:18940257562@163.com
作者简介:曾维玲(1993-),女,硕士研究生.



关键词: 透析后疲劳, 维持性血液透析, 超滤量, 睡眠质量, 影响因素
Abstract: Objective To analyze the influencing factors of post-dialysis fatigue in patients under maintenance hemodialysis (MHD). Methods A total of 75 patients under MHD in the second hemodialysis center of Shengjing Hospital of China Medical University were enrolled. They were investigated using the Revised Piper Fatigue Scale (RPFS),and the time of recovery from hemodialysis was recorded. All patients were divided into three different groups according to the tertiles of the RPFS score,and clinical data,sleep quality,and indicators before and after dialysis in these three groups were compared. Influencing factors for post-dialysis fatigue in patients under MHD were analyzed using the ordinal polytomous logistic regression method. Results A total of 70 questionnaires were effectively collected. The incidence of post-dialysis fatigue was noted in 78.57% of patients under MHD.Among the three groups,the recovery time after dialysis,interdialytic weight gain,ultrafiltration volume,and mean arterial pressure after dialysis showed significant difference (all P < 0.05). The logistic regression analysis showed that ultrafiltration volume (P=0.001),sleep quality (P=0.01),and mean arterial pressure after dialysis (P=0.029) were associated with post-dialysis fatigue. Conclusion Post-dialysis fatigue is a common occurrence in patients under MHD,and high ultrafiltration volume,low mean arterial pressure after dialysis,and poor sleep quality are risk factors associated with its occurrence.
Key words: post-dialysis fatigue, maintenance hemodialysis, ultrafiltration volume, sleep quality, influencing factor
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